NCT00099437

Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.

Version 10 to 11 · AstraZeneca

Patch inspector

Version 10 to 11

5 operations 2 path groups ctgov_internal_history

Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.

Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals

[
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_earlier_adjustment",
    "category": "timeline_minor_adjustment",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "low",
    "direction": "earlier",
    "new_value": "2009-02",
    "old_value": "2009-04",
    "delta_days": 59,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "month",
    "old_precision": "month"
  },
  {
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "signal": "timeline_shift",
    "category": "timeline_shift",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "later",
    "new_value": "2009-07",
    "old_value": "2009-06",
    "delta_days": 30,
    "date_struct": "completionDateStruct",
    "new_precision": "month",
    "old_precision": "month"
  }
]

Provenance

Source: ctgov_internal_history
Fetched: 2026-06-18 18:59:59+00
Raw hash: b2283c545397e201cfa378496f1813c0dacb9677015aba2988278c391dd95c9d
Payload: Source URL

Timeline Start, primary completion, and completion date movement. Triage: Medium 2 ops

replace /protocolSection/statusModule/primaryCompletionDateStruct/date

Triage: Medium

Timeline Shift Operation 2

Matched rules

primary_completion_timeline_change Primary completion date changes are operational timeline signals.

Before

2009-04

After

2009-02

replace /protocolSection/statusModule/completionDateStruct/date

Triage: Medium

Timeline Shift Operation 3

Matched rules

completion_timeline_change Completion date changes are operational timeline signals.

Before

2009-06

After

2009-07

Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops

replace /protocolSection/statusModule/statusVerifiedDate

Triage: Uncategorized

Uncategorized Operation 1

Before

2009-03

After

2009-04

replace /protocolSection/statusModule/lastUpdateSubmitDate

Triage: Uncategorized

Uncategorized Operation 4

Before

2009-03-13

After

2009-04-21

replace /protocolSection/statusModule/lastUpdatePostDateStruct/date

Triage: Uncategorized

Uncategorized Operation 5

Before

2009-03-16

After

2009-04-22

Raw JSON Patch

[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2009-04"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2009-02"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "value": "2009-07"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2009-04-21"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2009-04-22"
  }
]