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NCT00490139

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

Version 11 to 12 · Novartis Pharmaceuticals

Patch inspector

Version 11 to 12

54 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct",
    "reason": "date_unparsed_or_missing",
    "signal": "timeline_shift",
    "category": "timeline_shift",
    "new_type": "ESTIMATED",
    "old_type": null,
    "severity": "medium",
    "direction": "unknown",
    "new_value": "2012-06",
    "old_value": null,
    "date_struct": "primaryCompletionDateStruct"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:00:58+00
Raw hash
e39e61c868696256d9c598529acbb8b819876923bbe7ffec7d0642edd7591255
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 1 ops
add /protocolSection/statusModule/primaryCompletionDateStruct
Triage: Medium
Timeline Shift Operation 3
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
After
{
  "date": "2012-06",
  "type": "ESTIMATED"
}
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 51 ops
add /protocolSection/contactsLocationsModule/locations/1
Triage: Uncategorized
Uncategorized Operation 4
After
{
  "zip": "72401",
  "city": "Jonesboro",
  "state": "Arkansas",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Carroll Scroggin",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Center",
  "geoPoint": {
    "lat": 35.8423,
    "lon": -90.70428
  }
}
add /protocolSection/contactsLocationsModule/locations/5
Triage: Uncategorized
Uncategorized Operation 5
After
{
  "zip": "52403",
  "city": "Cedar Rapids",
  "state": "Iowa",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Martin Wiesenfeld",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Center",
  "geoPoint": {
    "lat": 42.00833,
    "lon": -91.64407
  }
}
add /protocolSection/contactsLocationsModule/locations/6
Triage: Uncategorized
Uncategorized Operation 6
After
{
  "zip": "50401",
  "city": "Mason City",
  "state": "Iowa",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Walter Bate",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Center",
  "geoPoint": {
    "lat": 43.15357,
    "lon": -93.20104
  }
}
add /protocolSection/contactsLocationsModule/locations/8
Triage: Uncategorized
Uncategorized Operation 7
After
{
  "zip": "28501",
  "city": "Kinston",
  "state": "North Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Peter Watson",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Center",
  "geoPoint": {
    "lat": 35.26266,
    "lon": -77.58164
  }
}
replace /protocolSection/contactsLocationsModule/locations/101/status
Triage: Uncategorized
Uncategorized Operation 8
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/101/zip
Triage: Uncategorized
Uncategorized Operation 9
Before
236-3058
After
2352499
replace /protocolSection/contactsLocationsModule/locations/102/status
Triage: Uncategorized
Uncategorized Operation 10
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/102/zip
Triage: Uncategorized
Uncategorized Operation 11
After
254-0364
replace /protocolSection/contactsLocationsModule/locations/103/status
Triage: Uncategorized
Uncategorized Operation 12
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/103/zip
Triage: Uncategorized
Uncategorized Operation 13
Before
100021
After
100071
remove /protocolSection/contactsLocationsModule/locations/214
Triage: Uncategorized
Uncategorized Operation 14
Before
{
  "zip": "71032",
  "city": "Bobingen",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 48.27091,
    "lon": 10.8339
  }
}
add /protocolSection/contactsLocationsModule/locations/219
Triage: Uncategorized
Uncategorized Operation 15
After
{
  "zip": "71032",
  "city": "Böblingen",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 48.68212,
    "lon": 9.01171
  }
}
remove /protocolSection/contactsLocationsModule/locations/350
Triage: Uncategorized
Uncategorized Operation 16
Before
{
  "zip": "57462",
  "city": "Oelde",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 51.8289,
    "lon": 8.14724
  }
}
add /protocolSection/contactsLocationsModule/locations/353
Triage: Uncategorized
Uncategorized Operation 17
After
{
  "zip": "57462",
  "city": "Olpe",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 51.02899,
    "lon": 7.85139
  }
}
add /protocolSection/contactsLocationsModule/locations/357
Triage: Uncategorized
Uncategorized Operation 18
After
{
  "zip": "88214",
  "city": "Ravensburg",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 47.78198,
    "lon": 9.61062
  }
}
remove /protocolSection/contactsLocationsModule/locations/362
Triage: Uncategorized
Uncategorized Operation 19
Before
{
  "zip": "88214",
  "city": "Revensburg",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre"
}
replace /protocolSection/contactsLocationsModule/locations/527/status
Triage: Uncategorized
Uncategorized Operation 20
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/531/status
Triage: Uncategorized
Uncategorized Operation 21
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/536/status
Triage: Uncategorized
Uncategorized Operation 22
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/536/zip
Triage: Uncategorized
Uncategorized Operation 23
Before
350-1241
After
350-1298
replace /protocolSection/contactsLocationsModule/locations/537/status
Triage: Uncategorized
Uncategorized Operation 24
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/537/zip
Triage: Uncategorized
Uncategorized Operation 25
Before
101-8643
After
101-0024
remove /protocolSection/contactsLocationsModule/locations/546/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 26
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/547/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 27
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/549/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 28
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/550/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 29
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/551/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 30
Before
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/589/status
Triage: Uncategorized
Uncategorized Operation 31
Before
RECRUITING
After
NOT_YET_RECRUITING
replace /protocolSection/contactsLocationsModule/locations/589/city
Triage: Uncategorized
Uncategorized Operation 32
Before
Lahore
After
Karachi
replace /protocolSection/contactsLocationsModule/locations/589/zip
Triage: Uncategorized
Uncategorized Operation 33
Before
53400
After
74800
remove /protocolSection/contactsLocationsModule/locations/589/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 34
Before
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/589/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 35
Before
31.558
After
24.8608
replace /protocolSection/contactsLocationsModule/locations/589/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 36
Before
74.35071
After
67.0104
add /protocolSection/contactsLocationsModule/locations/590
Triage: Uncategorized
Uncategorized Operation 37
After
{
  "zip": "53400",
  "city": "Lahore",
  "status": "RECRUITING",
  "country": "Pakistan",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 31.558,
    "lon": 74.35071
  }
}
remove /protocolSection/contactsLocationsModule/locations/600/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 38
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/601/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 39
Before
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/654/status
Triage: Uncategorized
Uncategorized Operation 40
Before
NOT_YET_RECRUITING
After
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/668/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 41
Before
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/670/status
Triage: Uncategorized
Uncategorized Operation 42
Before
NOT_YET_RECRUITING
After
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/670/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 43
Before
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/710/city
Triage: Uncategorized
Uncategorized Operation 44
Before
Salamanca
After
Pampplona
replace /protocolSection/contactsLocationsModule/locations/710/zip
Triage: Uncategorized
Uncategorized Operation 45
Before
37007
After
31008
remove /protocolSection/contactsLocationsModule/locations/710/geoPoint
Triage: Uncategorized
Uncategorized Operation 46
Before
{
  "lat": 40.96882,
  "lon": -5.66388
}
add /protocolSection/contactsLocationsModule/locations/711
Triage: Uncategorized
Uncategorized Operation 47
After
{
  "zip": "37007",
  "city": "Salamamca",
  "status": "NOT_YET_RECRUITING",
  "country": "Spain",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre"
}
replace /protocolSection/contactsLocationsModule/locations/742/facility
Triage: Uncategorized
Uncategorized Operation 48
Before
GSK Clinical Trials Call Centre
After
G
remove /protocolSection/contactsLocationsModule/locations/748/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 49
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/749/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 50
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/750/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 51
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/752/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 52
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/753/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 53
Before
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/757/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 54
Before
1 877 379 3718
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 2 ops
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2008-03-12
After
2008-03-19
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 2
Before
2008-03-13
After
2008-03-21
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2008-03-19"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2008-03-21"
  },
  {
    "op": "add",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct",
    "value": {
      "date": "2012-06",
      "type": "ESTIMATED"
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/1",
    "value": {
      "zip": "72401",
      "city": "Jonesboro",
      "state": "Arkansas",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Carroll Scroggin",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Center",
      "geoPoint": {
        "lat": 35.8423,
        "lon": -90.70428
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/5",
    "value": {
      "zip": "52403",
      "city": "Cedar Rapids",
      "state": "Iowa",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Martin Wiesenfeld",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Center",
      "geoPoint": {
        "lat": 42.00833,
        "lon": -91.64407
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/6",
    "value": {
      "zip": "50401",
      "city": "Mason City",
      "state": "Iowa",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Walter Bate",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Center",
      "geoPoint": {
        "lat": 43.15357,
        "lon": -93.20104
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/8",
    "value": {
      "zip": "28501",
      "city": "Kinston",
      "state": "North Carolina",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Peter Watson",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Center",
      "geoPoint": {
        "lat": 35.26266,
        "lon": -77.58164
      }
    }
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/101/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/101/zip",
    "value": "2352499"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/102/status",
    "value": "RECRUITING"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/102/zip",
    "value": "254-0364"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/103/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/103/zip",
    "value": "100071"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/214"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/219",
    "value": {
      "zip": "71032",
      "city": "Böblingen",
      "status": "RECRUITING",
      "country": "Germany",
      "contacts": [
        {
          "name": "GSK Clinical Trials Call Centre",
          "role": "CONTACT",
          "phone": "1 877 379 3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Centre",
      "geoPoint": {
        "lat": 48.68212,
        "lon": 9.01171
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/350"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/353",
    "value": {
      "zip": "57462",
      "city": "Olpe",
      "status": "RECRUITING",
      "country": "Germany",
      "contacts": [
        {
          "name": "GSK Clinical Trials Call Centre",
          "role": "CONTACT",
          "phone": "1 877 379 3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Centre",
      "geoPoint": {
        "lat": 51.02899,
        "lon": 7.85139
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/357",
    "value": {
      "zip": "88214",
      "city": "Ravensburg",
      "status": "RECRUITING",
      "country": "Germany",
      "contacts": [
        {
          "name": "GSK Clinical Trials Call Centre",
          "role": "CONTACT",
          "phone": "1 877 379 3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Centre",
      "geoPoint": {
        "lat": 47.78198,
        "lon": 9.61062
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/362"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/527/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/531/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/536/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/536/zip",
    "value": "350-1298"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/537/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/537/zip",
    "value": "101-0024"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/546/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/547/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/549/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/550/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/551/contacts/0/phone"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/589/status",
    "value": "NOT_YET_RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/589/city",
    "value": "Karachi"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/589/zip",
    "value": "74800"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/589/contacts/0/phone"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/589/geoPoint/lat",
    "value": 24.8608
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/589/geoPoint/lon",
    "value": 67.0104
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/590",
    "value": {
      "zip": "53400",
      "city": "Lahore",
      "status": "RECRUITING",
      "country": "Pakistan",
      "contacts": [
        {
          "name": "GSK Clinical Trials Call Centre",
          "role": "CONTACT"
        }
      ],
      "facility": "GSK Clinical Trials Call Centre",
      "geoPoint": {
        "lat": 31.558,
        "lon": 74.35071
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/600/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/601/contacts/0/phone"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/654/status",
    "value": "RECRUITING"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/668/contacts/0/phone"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/670/status",
    "value": "RECRUITING"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/670/contacts/0/phone"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/710/city",
    "value": "Pampplona"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/710/zip",
    "value": "31008"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/710/geoPoint"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/711",
    "value": {
      "zip": "37007",
      "city": "Salamamca",
      "status": "NOT_YET_RECRUITING",
      "country": "Spain",
      "contacts": [
        {
          "name": "GSK Clinical Trials Call Centre",
          "role": "CONTACT",
          "phone": "1 877 379 3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Centre"
    }
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/742/facility",
    "value": "G"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/748/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/749/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/750/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/752/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/753/contacts/0/phone"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/757/contacts/0/phone"
  }
]