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NCT00490139

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

Version 189 to 190 · Novartis Pharmaceuticals

Patch inspector

Version 189 to 190

7 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_actual_date_correction",
    "category": "timeline_actual_date_correction",
    "new_type": "ACTUAL",
    "old_type": "ACTUAL",
    "severity": "low",
    "direction": "later",
    "new_value": "2013-12",
    "old_value": "2011-06",
    "delta_days": 914,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "month",
    "old_precision": "month"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:02:31+00
Raw hash
9a79b61d0be505a1ceac6a7d10e03c1f08bd6da9af98a3453dfbd0551d5fd41e
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 1 ops
replace /protocolSection/statusModule/primaryCompletionDateStruct/date
Triage: Medium
Timeline Shift Operation 2
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
2011-06
After
2013-12
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 3 ops
replace /protocolSection/contactsLocationsModule/locations/1281/city
Triage: Uncategorized
Uncategorized Operation 5
Before
Suwon-si, Gyeonggi-do
After
Suwon
replace /protocolSection/contactsLocationsModule/locations/1281/zip
Triage: Uncategorized
Uncategorized Operation 6
Before
443-380
After
443-721
add /protocolSection/contactsLocationsModule/locations/1281/geoPoint
Triage: Uncategorized
Uncategorized Operation 7
After
{
  "lat": 37.29111,
  "lon": 127.00889
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2014-05
After
2014-06
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2014-05-22
After
2014-07-03
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2014-05-26
After
2014-07-08
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2014-06"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2013-12"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2014-07-03"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2014-07-08"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/1281/city",
    "value": "Suwon"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/1281/zip",
    "value": "443-721"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/1281/geoPoint",
    "value": {
      "lat": 37.29111,
      "lon": 127.00889
    }
  }
]