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NCT00490139

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

Version 6 to 7 · Novartis Pharmaceuticals

Patch inspector

Version 6 to 7

285 operations 4 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
primary_outcome_any_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:00:55+00
Raw hash
0c320c348e0670311374cdeb1035dac32ea3b8113f6e0c82b5c5bc542b4a204d
Payload
Source URL
Primary outcomes Outcome measures that define the trial's primary evidence target. Triage: Critical 1 ops
remove /protocolSection/outcomesModule/primaryOutcomes/0/timeFrame
Triage: Critical
Primary Outcome Change Operation 7
Matched rules
  • primary_outcome_any_change Any add/remove/replace under primary outcome measures is critical review priority.
Before
Overall survival
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 278 ops
add /protocolSection/contactsLocationsModule/locations/0
Triage: Uncategorized
Uncategorized Operation 8
After
{
  "zip": "33916",
  "city": "Fort Myers",
  "state": "Florida",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Thomas Ervin",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Center",
  "geoPoint": {
    "lat": 26.62168,
    "lon": -81.84059
  }
}
add /protocolSection/contactsLocationsModule/locations/1
Triage: Uncategorized
Uncategorized Operation 9
After
{
  "zip": "45242",
  "city": "Cincinnati",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Patrick Ward",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinial Trials Call Center",
  "geoPoint": {
    "lat": 39.12711,
    "lon": -84.51439
  }
}
add /protocolSection/contactsLocationsModule/locations/2
Triage: Uncategorized
Uncategorized Operation 10
After
{
  "zip": "37404",
  "city": "Chattanooga",
  "state": "Tennessee",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Brooke Daniel",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Center",
  "geoPoint": {
    "lat": 35.04563,
    "lon": -85.30968
  }
}
add /protocolSection/contactsLocationsModule/locations/3
Triage: Uncategorized
Uncategorized Operation 11
After
{
  "zip": "37203",
  "city": "Nashville",
  "state": "Tennessee",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Denise Yardley",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Center",
  "geoPoint": {
    "lat": 36.16589,
    "lon": -86.78444
  }
}
add /protocolSection/contactsLocationsModule/locations/4
Triage: Uncategorized
Uncategorized Operation 12
After
{
  "zip": "23230",
  "city": "Richmond",
  "state": "Virginia",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "David Trent",
      "role": "CONTACT",
      "phone": "877-379-3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Center",
  "geoPoint": {
    "lat": 37.55376,
    "lon": -77.46026
  }
}
replace /protocolSection/contactsLocationsModule/locations/6/status
Triage: Uncategorized
Uncategorized Operation 13
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/46/status
Triage: Uncategorized
Uncategorized Operation 14
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/48/status
Triage: Uncategorized
Uncategorized Operation 15
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/50/status
Triage: Uncategorized
Uncategorized Operation 16
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/52/status
Triage: Uncategorized
Uncategorized Operation 17
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/53/status
Triage: Uncategorized
Uncategorized Operation 18
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/55/status
Triage: Uncategorized
Uncategorized Operation 19
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/56/status
Triage: Uncategorized
Uncategorized Operation 20
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/57/status
Triage: Uncategorized
Uncategorized Operation 21
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/59/status
Triage: Uncategorized
Uncategorized Operation 22
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/61/status
Triage: Uncategorized
Uncategorized Operation 23
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/62/status
Triage: Uncategorized
Uncategorized Operation 24
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/63/status
Triage: Uncategorized
Uncategorized Operation 25
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/66/status
Triage: Uncategorized
Uncategorized Operation 26
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/67/status
Triage: Uncategorized
Uncategorized Operation 27
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/68/status
Triage: Uncategorized
Uncategorized Operation 28
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/68/city
Triage: Uncategorized
Uncategorized Operation 29
Before
Saint Niklaas
After
Sint-Niklaas
add /protocolSection/contactsLocationsModule/locations/68/geoPoint
Triage: Uncategorized
Uncategorized Operation 30
After
{
  "lat": 51.16509,
  "lon": 4.1437
}
replace /protocolSection/contactsLocationsModule/locations/71/status
Triage: Uncategorized
Uncategorized Operation 31
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/72/status
Triage: Uncategorized
Uncategorized Operation 32
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/73/status
Triage: Uncategorized
Uncategorized Operation 33
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/80
Triage: Uncategorized
Uncategorized Operation 34
After
{
  "zip": "4000",
  "city": "Plovdiv",
  "status": "NOT_YET_RECRUITING",
  "country": "Bulgaria",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 42.15387,
    "lon": 24.75001
  }
}
replace /protocolSection/contactsLocationsModule/locations/83/zip
Triage: Uncategorized
Uncategorized Operation 35
Before
1572
After
1527
add /protocolSection/contactsLocationsModule/locations/84
Triage: Uncategorized
Uncategorized Operation 36
After
{
  "zip": "1756",
  "city": "Sofia",
  "status": "NOT_YET_RECRUITING",
  "country": "Bulgaria",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 42.69751,
    "lon": 23.32415
  }
}
replace /protocolSection/contactsLocationsModule/locations/86/city
Triage: Uncategorized
Uncategorized Operation 37
Before
Veliko Tarnovo
After
Varna
replace /protocolSection/contactsLocationsModule/locations/86/zip
Triage: Uncategorized
Uncategorized Operation 38
Before
5000
After
9010
replace /protocolSection/contactsLocationsModule/locations/86/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 39
Before
43.08124
After
43.21912
replace /protocolSection/contactsLocationsModule/locations/86/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 40
Before
25.62904
After
27.91024
add /protocolSection/contactsLocationsModule/locations/87
Triage: Uncategorized
Uncategorized Operation 41
After
{
  "zip": "5000",
  "city": "Veliko Tarnovo",
  "status": "ACTIVE_NOT_RECRUITING",
  "country": "Bulgaria",
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 43.08124,
    "lon": 25.62904
  }
}
replace /protocolSection/contactsLocationsModule/locations/98/status
Triage: Uncategorized
Uncategorized Operation 42
Before
NOT_YET_RECRUITING
After
ACTIVE_NOT_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/98/contacts
Triage: Uncategorized
Uncategorized Operation 43
Before
[
  {
    "name": "GSK Clinical Trials Call Centre",
    "role": "CONTACT",
    "phone": "1 877 379 3718"
  }
]
replace /protocolSection/contactsLocationsModule/locations/99/status
Triage: Uncategorized
Uncategorized Operation 44
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/100/status
Triage: Uncategorized
Uncategorized Operation 45
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/101/status
Triage: Uncategorized
Uncategorized Operation 46
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/102/status
Triage: Uncategorized
Uncategorized Operation 47
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/103/status
Triage: Uncategorized
Uncategorized Operation 48
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/104/status
Triage: Uncategorized
Uncategorized Operation 49
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/105/status
Triage: Uncategorized
Uncategorized Operation 50
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/106/status
Triage: Uncategorized
Uncategorized Operation 51
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/107/status
Triage: Uncategorized
Uncategorized Operation 52
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/108/status
Triage: Uncategorized
Uncategorized Operation 53
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/109/status
Triage: Uncategorized
Uncategorized Operation 54
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/110/status
Triage: Uncategorized
Uncategorized Operation 55
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/112/status
Triage: Uncategorized
Uncategorized Operation 56
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/113/status
Triage: Uncategorized
Uncategorized Operation 57
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/114/status
Triage: Uncategorized
Uncategorized Operation 58
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/115/status
Triage: Uncategorized
Uncategorized Operation 59
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/116/status
Triage: Uncategorized
Uncategorized Operation 60
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/117/status
Triage: Uncategorized
Uncategorized Operation 61
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/118/status
Triage: Uncategorized
Uncategorized Operation 62
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/119/status
Triage: Uncategorized
Uncategorized Operation 63
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/120/status
Triage: Uncategorized
Uncategorized Operation 64
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/121/status
Triage: Uncategorized
Uncategorized Operation 65
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/122/status
Triage: Uncategorized
Uncategorized Operation 66
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/123
Triage: Uncategorized
Uncategorized Operation 67
After
{
  "zip": "8800",
  "city": "Viborg",
  "status": "RECRUITING",
  "country": "Denmark",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 56.45319,
    "lon": 9.40201
  }
}
add /protocolSection/contactsLocationsModule/locations/128
Triage: Uncategorized
Uncategorized Operation 68
After
{
  "zip": "74000",
  "city": "Annecy",
  "status": "RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 45.90878,
    "lon": 6.12565
  }
}
add /protocolSection/contactsLocationsModule/locations/129
Triage: Uncategorized
Uncategorized Operation 69
After
{
  "zip": "84000",
  "city": "Avignon",
  "status": "NOT_YET_RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 43.94834,
    "lon": 4.80892
  }
}
add /protocolSection/contactsLocationsModule/locations/130
Triage: Uncategorized
Uncategorized Operation 70
After
{
  "zip": "64100",
  "city": "Bayonne",
  "status": "RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 43.49316,
    "lon": -1.473
  }
}
replace /protocolSection/contactsLocationsModule/locations/132/status
Triage: Uncategorized
Uncategorized Operation 71
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/133/status
Triage: Uncategorized
Uncategorized Operation 72
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/135/city
Triage: Uncategorized
Uncategorized Operation 73
Before
Clermont-Ferrand
After
Clrmont Ferrand
remove /protocolSection/contactsLocationsModule/locations/135/geoPoint
Triage: Uncategorized
Uncategorized Operation 74
Before
{
  "lat": 45.77969,
  "lon": 3.08682
}
add /protocolSection/contactsLocationsModule/locations/136
Triage: Uncategorized
Uncategorized Operation 75
After
{
  "zip": "91106",
  "city": "Corbeil-Essonnes",
  "status": "NOT_YET_RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 48.60603,
    "lon": 2.48757
  }
}
replace /protocolSection/contactsLocationsModule/locations/138/status
Triage: Uncategorized
Uncategorized Operation 76
Before
NOT_YET_RECRUITING
After
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replace /protocolSection/contactsLocationsModule/locations/139/status
Triage: Uncategorized
Uncategorized Operation 77
Before
NOT_YET_RECRUITING
After
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replace /protocolSection/contactsLocationsModule/locations/140/status
Triage: Uncategorized
Uncategorized Operation 78
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/141/city
Triage: Uncategorized
Uncategorized Operation 79
Before
Le Chesnay
After
La Seyne-sur-Mer
replace /protocolSection/contactsLocationsModule/locations/141/zip
Triage: Uncategorized
Uncategorized Operation 80
Before
78157
After
83500
replace /protocolSection/contactsLocationsModule/locations/141/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 81
Before
48.8222
After
43.10322
replace /protocolSection/contactsLocationsModule/locations/141/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 82
Before
2.12213
After
5.87816
replace /protocolSection/contactsLocationsModule/locations/142/status
Triage: Uncategorized
Uncategorized Operation 83
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/142/city
Triage: Uncategorized
Uncategorized Operation 84
Before
Le Havre
After
Le Chesnay
replace /protocolSection/contactsLocationsModule/locations/142/zip
Triage: Uncategorized
Uncategorized Operation 85
Before
76600
After
78157
replace /protocolSection/contactsLocationsModule/locations/142/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 86
Before
49.49346
After
48.8222
replace /protocolSection/contactsLocationsModule/locations/142/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 87
Before
0.10785
After
2.12213
replace /protocolSection/contactsLocationsModule/locations/143/status
Triage: Uncategorized
Uncategorized Operation 88
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/143/city
Triage: Uncategorized
Uncategorized Operation 89
Before
Le Mans
After
Le Havre
replace /protocolSection/contactsLocationsModule/locations/143/zip
Triage: Uncategorized
Uncategorized Operation 90
Before
72000
After
76600
replace /protocolSection/contactsLocationsModule/locations/143/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 91
Before
48.0021
After
49.49346
replace /protocolSection/contactsLocationsModule/locations/143/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 92
Before
0.20251
After
0.10785
replace /protocolSection/contactsLocationsModule/locations/144/status
Triage: Uncategorized
Uncategorized Operation 93
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/144/zip
Triage: Uncategorized
Uncategorized Operation 94
Before
72015
After
72000
replace /protocolSection/contactsLocationsModule/locations/145/status
Triage: Uncategorized
Uncategorized Operation 95
Before
NOT_YET_RECRUITING
After
ACTIVE_NOT_RECRUITING
replace /protocolSection/contactsLocationsModule/locations/145/city
Triage: Uncategorized
Uncategorized Operation 96
Before
Levallois-Perret
After
Le Mans
replace /protocolSection/contactsLocationsModule/locations/145/zip
Triage: Uncategorized
Uncategorized Operation 97
Before
92300
After
72015
remove /protocolSection/contactsLocationsModule/locations/145/contacts
Triage: Uncategorized
Uncategorized Operation 98
Before
[
  {
    "name": "GSK Clinical Trials Call Centre",
    "role": "CONTACT",
    "phone": "1 877 379 3718"
  }
]
replace /protocolSection/contactsLocationsModule/locations/145/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 99
Before
48.89389
After
48.0021
replace /protocolSection/contactsLocationsModule/locations/145/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 100
Before
2.28864
After
0.20251
add /protocolSection/contactsLocationsModule/locations/146
Triage: Uncategorized
Uncategorized Operation 101
After
{
  "zip": "92300",
  "city": "Levallois-Perret",
  "status": "ACTIVE_NOT_RECRUITING",
  "country": "France",
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 48.89389,
    "lon": 2.28864
  }
}
add /protocolSection/contactsLocationsModule/locations/150
Triage: Uncategorized
Uncategorized Operation 102
After
{
  "zip": "69009",
  "city": "Lyon",
  "status": "RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 45.74906,
    "lon": 4.84789
  }
}
add /protocolSection/contactsLocationsModule/locations/153
Triage: Uncategorized
Uncategorized Operation 103
After
{
  "zip": "13285",
  "city": "Marseille",
  "status": "NOT_YET_RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 43.29695,
    "lon": 5.38107
  }
}
add /protocolSection/contactsLocationsModule/locations/155
Triage: Uncategorized
Uncategorized Operation 104
After
{
  "zip": "25200",
  "city": "Montbéliard",
  "status": "RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 47.50957,
    "lon": 6.79823
  }
}
add /protocolSection/contactsLocationsModule/locations/158
Triage: Uncategorized
Uncategorized Operation 105
After
{
  "zip": "06189",
  "city": "Nice",
  "status": "RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 43.70313,
    "lon": 7.26608
  }
}
add /protocolSection/contactsLocationsModule/locations/160
Triage: Uncategorized
Uncategorized Operation 106
After
{
  "zip": "75475",
  "city": "Paris",
  "status": "NOT_YET_RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 48.85341,
    "lon": 2.3488
  }
}
replace /protocolSection/contactsLocationsModule/locations/162/status
Triage: Uncategorized
Uncategorized Operation 107
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/164/status
Triage: Uncategorized
Uncategorized Operation 108
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/165/status
Triage: Uncategorized
Uncategorized Operation 109
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/166/city
Triage: Uncategorized
Uncategorized Operation 110
Before
Saint-Grégoire
After
Saint-Cloud
replace /protocolSection/contactsLocationsModule/locations/166/zip
Triage: Uncategorized
Uncategorized Operation 111
Before
35760
After
92210
replace /protocolSection/contactsLocationsModule/locations/166/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 112
Before
48.15101
After
48.84598
replace /protocolSection/contactsLocationsModule/locations/166/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 113
Before
-1.68579
After
2.20289
add /protocolSection/contactsLocationsModule/locations/167
Triage: Uncategorized
Uncategorized Operation 114
After
{
  "zip": "35760",
  "city": "Saint-Grégoire",
  "status": "RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 48.15101,
    "lon": -1.68579
  }
}
replace /protocolSection/contactsLocationsModule/locations/170/status
Triage: Uncategorized
Uncategorized Operation 115
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/173
Triage: Uncategorized
Uncategorized Operation 116
After
{
  "zip": "31076",
  "city": "Toulouse",
  "status": "RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 43.60426,
    "lon": 1.44367
  }
}
add /protocolSection/contactsLocationsModule/locations/174
Triage: Uncategorized
Uncategorized Operation 117
After
{
  "zip": "31077",
  "city": "Toulouse",
  "status": "RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 43.60426,
    "lon": 1.44367
  }
}
add /protocolSection/contactsLocationsModule/locations/178
Triage: Uncategorized
Uncategorized Operation 118
After
{
  "zip": "59322",
  "city": "Valenciennes",
  "status": "NOT_YET_RECRUITING",
  "country": "France",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 50.35909,
    "lon": 3.52506
  }
}
replace /protocolSection/contactsLocationsModule/locations/180/status
Triage: Uncategorized
Uncategorized Operation 119
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/183/status
Triage: Uncategorized
Uncategorized Operation 120
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/188/status
Triage: Uncategorized
Uncategorized Operation 121
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/189/status
Triage: Uncategorized
Uncategorized Operation 122
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/193/status
Triage: Uncategorized
Uncategorized Operation 123
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/194/status
Triage: Uncategorized
Uncategorized Operation 124
Before
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After
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replace /protocolSection/contactsLocationsModule/locations/195/status
Triage: Uncategorized
Uncategorized Operation 125
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/196/status
Triage: Uncategorized
Uncategorized Operation 126
Before
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replace /protocolSection/contactsLocationsModule/locations/197/status
Triage: Uncategorized
Uncategorized Operation 127
Before
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replace /protocolSection/contactsLocationsModule/locations/208/status
Triage: Uncategorized
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Before
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After
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replace /protocolSection/contactsLocationsModule/locations/211/status
Triage: Uncategorized
Uncategorized Operation 129
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/214/status
Triage: Uncategorized
Uncategorized Operation 130
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/217/status
Triage: Uncategorized
Uncategorized Operation 131
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/220/status
Triage: Uncategorized
Uncategorized Operation 132
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/220/city
Triage: Uncategorized
Uncategorized Operation 133
Before
Cuxhaven
After
Cologne
replace /protocolSection/contactsLocationsModule/locations/220/zip
Triage: Uncategorized
Uncategorized Operation 134
Before
27474
After
50937
replace /protocolSection/contactsLocationsModule/locations/220/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 135
Before
53.86828
After
50.93333
replace /protocolSection/contactsLocationsModule/locations/220/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 136
Before
8.69902
After
6.95
add /protocolSection/contactsLocationsModule/locations/221
Triage: Uncategorized
Uncategorized Operation 137
After
{
  "zip": "27474",
  "city": "Cuxhaven",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 53.86828,
    "lon": 8.69902
  }
}
replace /protocolSection/contactsLocationsModule/locations/223/status
Triage: Uncategorized
Uncategorized Operation 138
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/225/status
Triage: Uncategorized
Uncategorized Operation 139
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/226/status
Triage: Uncategorized
Uncategorized Operation 140
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/233/status
Triage: Uncategorized
Uncategorized Operation 141
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/235/status
Triage: Uncategorized
Uncategorized Operation 142
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/236
Triage: Uncategorized
Uncategorized Operation 143
After
{
  "zip": "73730",
  "city": "Esslingen am Neckar",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 48.73961,
    "lon": 9.30473
  }
}
replace /protocolSection/contactsLocationsModule/locations/239/status
Triage: Uncategorized
Uncategorized Operation 144
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/241
Triage: Uncategorized
Uncategorized Operation 145
After
{
  "zip": "65929",
  "city": "Frankfurt",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 49.68333,
    "lon": 10.53333
  }
}
replace /protocolSection/contactsLocationsModule/locations/243/status
Triage: Uncategorized
Uncategorized Operation 146
Before
NOT_YET_RECRUITING
After
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/246
Triage: Uncategorized
Uncategorized Operation 147
Before
{
  "zip": "15517",
  "city": "Fürstenwalde",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 52.36067,
    "lon": 14.06185
  }
}
replace /protocolSection/contactsLocationsModule/locations/247/status
Triage: Uncategorized
Uncategorized Operation 148
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/250/status
Triage: Uncategorized
Uncategorized Operation 149
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/251/status
Triage: Uncategorized
Uncategorized Operation 150
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/255/status
Triage: Uncategorized
Uncategorized Operation 151
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/258/status
Triage: Uncategorized
Uncategorized Operation 152
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/259/status
Triage: Uncategorized
Uncategorized Operation 153
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/259/city
Triage: Uncategorized
Uncategorized Operation 154
Before
Hagen
After
Halle
replace /protocolSection/contactsLocationsModule/locations/259/zip
Triage: Uncategorized
Uncategorized Operation 155
Before
31785
After
06097
replace /protocolSection/contactsLocationsModule/locations/259/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 156
Before
51.36081
After
51.48158
replace /protocolSection/contactsLocationsModule/locations/259/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 157
Before
7.47168
After
11.97947
remove /protocolSection/contactsLocationsModule/locations/260
Triage: Uncategorized
Uncategorized Operation 158
Before
{
  "zip": "06097",
  "city": "Halle",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 51.48158,
    "lon": 11.97947
  }
}
replace /protocolSection/contactsLocationsModule/locations/261/status
Triage: Uncategorized
Uncategorized Operation 159
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/264/status
Triage: Uncategorized
Uncategorized Operation 160
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/265/status
Triage: Uncategorized
Uncategorized Operation 161
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/266/city
Triage: Uncategorized
Uncategorized Operation 162
Before
Hamm-Heessen
After
Hamelin
replace /protocolSection/contactsLocationsModule/locations/266/zip
Triage: Uncategorized
Uncategorized Operation 163
Before
59073
After
31785
add /protocolSection/contactsLocationsModule/locations/266/geoPoint
Triage: Uncategorized
Uncategorized Operation 164
After
{
  "lat": 52.10397,
  "lon": 9.35623
}
replace /protocolSection/contactsLocationsModule/locations/267/status
Triage: Uncategorized
Uncategorized Operation 165
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/267/city
Triage: Uncategorized
Uncategorized Operation 166
Before
Hanover
After
Hamm-Heessen
replace /protocolSection/contactsLocationsModule/locations/267/zip
Triage: Uncategorized
Uncategorized Operation 167
Before
30167
After
59073
remove /protocolSection/contactsLocationsModule/locations/267/geoPoint
Triage: Uncategorized
Uncategorized Operation 168
Before
{
  "lat": 52.37052,
  "lon": 9.73322
}
replace /protocolSection/contactsLocationsModule/locations/268/status
Triage: Uncategorized
Uncategorized Operation 169
Before
NOT_YET_RECRUITING
After
ACTIVE_NOT_RECRUITING
replace /protocolSection/contactsLocationsModule/locations/268/zip
Triage: Uncategorized
Uncategorized Operation 170
Before
30559
After
30167
remove /protocolSection/contactsLocationsModule/locations/268/contacts
Triage: Uncategorized
Uncategorized Operation 171
Before
[
  {
    "name": "GSK Clinical Trials Call Centre",
    "role": "CONTACT",
    "phone": "1 877 379 3718"
  }
]
add /protocolSection/contactsLocationsModule/locations/269
Triage: Uncategorized
Uncategorized Operation 172
After
{
  "zip": "30559",
  "city": "Hanover",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 52.37052,
    "lon": 9.73322
  }
}
add /protocolSection/contactsLocationsModule/locations/272
Triage: Uncategorized
Uncategorized Operation 173
After
{
  "zip": "69115",
  "city": "Heidelberg",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 49.40768,
    "lon": 8.69079
  }
}
replace /protocolSection/contactsLocationsModule/locations/276/status
Triage: Uncategorized
Uncategorized Operation 174
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/277/status
Triage: Uncategorized
Uncategorized Operation 175
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/278/status
Triage: Uncategorized
Uncategorized Operation 176
Before
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After
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remove /protocolSection/contactsLocationsModule/locations/282
Triage: Uncategorized
Uncategorized Operation 177
Before
{
  "zip": "07743",
  "city": "Jena",
  "status": "ACTIVE_NOT_RECRUITING",
  "country": "Germany",
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 50.92878,
    "lon": 11.5899
  }
}
replace /protocolSection/contactsLocationsModule/locations/286/status
Triage: Uncategorized
Uncategorized Operation 178
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/287/status
Triage: Uncategorized
Uncategorized Operation 179
Before
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RECRUITING
replace /protocolSection/contactsLocationsModule/locations/288/status
Triage: Uncategorized
Uncategorized Operation 180
Before
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replace /protocolSection/contactsLocationsModule/locations/289/status
Triage: Uncategorized
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replace /protocolSection/contactsLocationsModule/locations/291/status
Triage: Uncategorized
Uncategorized Operation 182
Before
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replace /protocolSection/contactsLocationsModule/locations/298/status
Triage: Uncategorized
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Before
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replace /protocolSection/contactsLocationsModule/locations/305/status
Triage: Uncategorized
Uncategorized Operation 184
Before
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After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/307/zip
Triage: Uncategorized
Uncategorized Operation 185
Before
39104
After
39108
remove /protocolSection/contactsLocationsModule/locations/308
Triage: Uncategorized
Uncategorized Operation 186
Before
{
  "zip": "39108",
  "city": "Magdeburg",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 52.13129,
    "lon": 11.63189
  }
}
remove /protocolSection/contactsLocationsModule/locations/309
Triage: Uncategorized
Uncategorized Operation 187
Before
{
  "zip": "55131",
  "city": "Mainz",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 49.98185,
    "lon": 8.28008
  }
}
replace /protocolSection/contactsLocationsModule/locations/310/status
Triage: Uncategorized
Uncategorized Operation 188
Before
ACTIVE_NOT_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/310/contacts
Triage: Uncategorized
Uncategorized Operation 189
After
[
  {
    "name": "GSK Clinical Trials Call Centre",
    "role": "CONTACT",
    "phone": "1 877 379 3718"
  }
]
replace /protocolSection/contactsLocationsModule/locations/311/status
Triage: Uncategorized
Uncategorized Operation 190
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/312/status
Triage: Uncategorized
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Before
NOT_YET_RECRUITING
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replace /protocolSection/contactsLocationsModule/locations/315/status
Triage: Uncategorized
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Before
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After
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replace /protocolSection/contactsLocationsModule/locations/317/status
Triage: Uncategorized
Uncategorized Operation 193
Before
NOT_YET_RECRUITING
After
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/318
Triage: Uncategorized
Uncategorized Operation 194
Before
{
  "zip": "99974",
  "city": "Muehljausen",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre"
}
replace /protocolSection/contactsLocationsModule/locations/320/city
Triage: Uncategorized
Uncategorized Operation 195
Before
Mülheim
After
Mühlhausen
replace /protocolSection/contactsLocationsModule/locations/320/zip
Triage: Uncategorized
Uncategorized Operation 196
Before
45473
After
99974
replace /protocolSection/contactsLocationsModule/locations/320/geoPoint/lat
Triage: Uncategorized
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Before
51.43218
After
51.20896
replace /protocolSection/contactsLocationsModule/locations/320/geoPoint/lon
Triage: Uncategorized
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Before
6.87967
After
10.45275
replace /protocolSection/contactsLocationsModule/locations/321/status
Triage: Uncategorized
Uncategorized Operation 199
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/321/city
Triage: Uncategorized
Uncategorized Operation 200
Before
München
After
Mülheim
replace /protocolSection/contactsLocationsModule/locations/321/zip
Triage: Uncategorized
Uncategorized Operation 201
Before
80331
After
45473
replace /protocolSection/contactsLocationsModule/locations/321/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 202
Before
51.60698
After
51.43218
replace /protocolSection/contactsLocationsModule/locations/321/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 203
Before
13.31243
After
6.87967
add /protocolSection/contactsLocationsModule/locations/322
Triage: Uncategorized
Uncategorized Operation 204
After
{
  "zip": "80331",
  "city": "München",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 51.60698,
    "lon": 13.31243
  }
}
replace /protocolSection/contactsLocationsModule/locations/324/status
Triage: Uncategorized
Uncategorized Operation 205
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/325/status
Triage: Uncategorized
Uncategorized Operation 206
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/328/status
Triage: Uncategorized
Uncategorized Operation 207
Before
NOT_YET_RECRUITING
After
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/329
Triage: Uncategorized
Uncategorized Operation 208
Before
{
  "zip": "81925",
  "city": "München",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 51.60698,
    "lon": 13.31243
  }
}
replace /protocolSection/contactsLocationsModule/locations/331/status
Triage: Uncategorized
Uncategorized Operation 209
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/331/zip
Triage: Uncategorized
Uncategorized Operation 210
Before
48149
After
48153
remove /protocolSection/contactsLocationsModule/locations/332
Triage: Uncategorized
Uncategorized Operation 211
Before
{
  "zip": "48153",
  "city": "Münster",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 51.96236,
    "lon": 7.62571
  }
}
replace /protocolSection/contactsLocationsModule/locations/333/status
Triage: Uncategorized
Uncategorized Operation 212
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/338/status
Triage: Uncategorized
Uncategorized Operation 213
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/341/status
Triage: Uncategorized
Uncategorized Operation 214
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/343/status
Triage: Uncategorized
Uncategorized Operation 215
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/344/status
Triage: Uncategorized
Uncategorized Operation 216
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/345/status
Triage: Uncategorized
Uncategorized Operation 217
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/347/status
Triage: Uncategorized
Uncategorized Operation 218
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/348/status
Triage: Uncategorized
Uncategorized Operation 219
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/348/city
Triage: Uncategorized
Uncategorized Operation 220
Before
Rheinfelden
After
Revensburg
replace /protocolSection/contactsLocationsModule/locations/348/zip
Triage: Uncategorized
Uncategorized Operation 221
Before
79618
After
88214
remove /protocolSection/contactsLocationsModule/locations/348/geoPoint
Triage: Uncategorized
Uncategorized Operation 222
Before
{
  "lat": 47.56013,
  "lon": 7.78715
}
replace /protocolSection/contactsLocationsModule/locations/349/status
Triage: Uncategorized
Uncategorized Operation 223
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/349/city
Triage: Uncategorized
Uncategorized Operation 224
Before
Rodewisch
After
Rheinfelden
replace /protocolSection/contactsLocationsModule/locations/349/zip
Triage: Uncategorized
Uncategorized Operation 225
Before
08228
After
79618
replace /protocolSection/contactsLocationsModule/locations/349/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 226
Before
50.53083
After
47.56013
replace /protocolSection/contactsLocationsModule/locations/349/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 227
Before
12.41329
After
7.78715
add /protocolSection/contactsLocationsModule/locations/350
Triage: Uncategorized
Uncategorized Operation 228
After
{
  "zip": "08228",
  "city": "Rodewisch",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 50.53083,
    "lon": 12.41329
  }
}
replace /protocolSection/contactsLocationsModule/locations/352/status
Triage: Uncategorized
Uncategorized Operation 229
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/354/city
Triage: Uncategorized
Uncategorized Operation 230
Before
Rottweil
After
Rotenburg (Wümme)
replace /protocolSection/contactsLocationsModule/locations/354/zip
Triage: Uncategorized
Uncategorized Operation 231
Before
78628
After
27356
replace /protocolSection/contactsLocationsModule/locations/354/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 232
Before
48.16783
After
53.11032
replace /protocolSection/contactsLocationsModule/locations/354/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 233
Before
8.62719
After
9.4036
add /protocolSection/contactsLocationsModule/locations/355
Triage: Uncategorized
Uncategorized Operation 234
After
{
  "zip": "78628",
  "city": "Rotweil",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre"
}
add /protocolSection/contactsLocationsModule/locations/356
Triage: Uncategorized
Uncategorized Operation 235
After
{
  "zip": "66113",
  "city": "Saarbrücken",
  "status": "RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 49.23262,
    "lon": 7.00982
  }
}
replace /protocolSection/contactsLocationsModule/locations/361/status
Triage: Uncategorized
Uncategorized Operation 236
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/363/status
Triage: Uncategorized
Uncategorized Operation 237
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/365/status
Triage: Uncategorized
Uncategorized Operation 238
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/366/status
Triage: Uncategorized
Uncategorized Operation 239
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/367/status
Triage: Uncategorized
Uncategorized Operation 240
Before
NOT_YET_RECRUITING
After
ACTIVE_NOT_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/367/contacts
Triage: Uncategorized
Uncategorized Operation 241
Before
[
  {
    "name": "GSK Clinical Trials Call Centre",
    "role": "CONTACT",
    "phone": "1 877 379 3718"
  }
]
replace /protocolSection/contactsLocationsModule/locations/374/status
Triage: Uncategorized
Uncategorized Operation 242
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/375/status
Triage: Uncategorized
Uncategorized Operation 243
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/377/status
Triage: Uncategorized
Uncategorized Operation 244
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/380/status
Triage: Uncategorized
Uncategorized Operation 245
Before
NOT_YET_RECRUITING
After
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/383
Triage: Uncategorized
Uncategorized Operation 246
Before
{
  "zip": "92637",
  "city": "Weiden",
  "status": "NOT_YET_RECRUITING",
  "country": "Germany",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 49.67682,
    "lon": 12.15613
  }
}
replace /protocolSection/contactsLocationsModule/locations/387/status
Triage: Uncategorized
Uncategorized Operation 247
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/389/status
Triage: Uncategorized
Uncategorized Operation 248
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/390/status
Triage: Uncategorized
Uncategorized Operation 249
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/391/status
Triage: Uncategorized
Uncategorized Operation 250
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/392/status
Triage: Uncategorized
Uncategorized Operation 251
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/395/status
Triage: Uncategorized
Uncategorized Operation 252
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/453/status
Triage: Uncategorized
Uncategorized Operation 253
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/458/city
Triage: Uncategorized
Uncategorized Operation 254
Before
Fermo
After
Fermo (AP)
add /protocolSection/contactsLocationsModule/locations/518/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 255
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/520/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 256
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/521/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 257
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/522/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 258
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/523/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 259
After
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/560/status
Triage: Uncategorized
Uncategorized Operation 260
Before
NOT_YET_RECRUITING
After
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/560/city
Triage: Uncategorized
Uncategorized Operation 261
Before
Karachi
After
Lahore
replace /protocolSection/contactsLocationsModule/locations/560/zip
Triage: Uncategorized
Uncategorized Operation 262
Before
74800
After
53400
add /protocolSection/contactsLocationsModule/locations/560/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 263
After
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/560/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 264
Before
24.8608
After
31.558
replace /protocolSection/contactsLocationsModule/locations/560/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 265
Before
67.0104
After
74.35071
replace /protocolSection/contactsLocationsModule/locations/561/zip
Triage: Uncategorized
Uncategorized Operation 266
Before
53400
After
54000
add /protocolSection/contactsLocationsModule/locations/561/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 267
After
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/562
Triage: Uncategorized
Uncategorized Operation 268
Before
{
  "zip": "54000",
  "city": "Lahore",
  "status": "NOT_YET_RECRUITING",
  "country": "Pakistan",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT",
      "phone": "1 877 379 3718"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 31.558,
    "lon": 74.35071
  }
}
add /protocolSection/contactsLocationsModule/locations/567/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 269
After
1-877-379-3718
replace /protocolSection/contactsLocationsModule/locations/568/status
Triage: Uncategorized
Uncategorized Operation 270
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/570/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 271
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/571/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 272
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/627/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 273
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/629/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 274
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/696/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 275
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/700/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 276
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/701/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 277
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/702/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 278
After
1 877 379 3718
add /protocolSection/contactsLocationsModule/locations/704/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 279
After
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/706/status
Triage: Uncategorized
Uncategorized Operation 280
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/706/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 281
After
1 877 379 3718
remove /protocolSection/contactsLocationsModule/locations/707
Triage: Uncategorized
Uncategorized Operation 282
Before
{
  "zip": "10400",
  "city": "Bangkok",
  "status": "RECRUITING",
  "country": "Thailand",
  "contacts": [
    {
      "name": "GSK Clinical Trials Call Centre",
      "role": "CONTACT"
    }
  ],
  "facility": "GSK Clinical Trials Call Centre",
  "geoPoint": {
    "lat": 13.75398,
    "lon": 100.50144
  }
}
add /protocolSection/contactsLocationsModule/locations/710/contacts/0/phone
Triage: Uncategorized
Uncategorized Operation 283
After
1 877 379 3718
replace /protocolSection/contactsLocationsModule/locations/766/city
Triage: Uncategorized
Uncategorized Operation 284
Before
Romfprd
After
Romford
add /protocolSection/contactsLocationsModule/locations/766/geoPoint
Triage: Uncategorized
Uncategorized Operation 285
After
{
  "lat": 51.57515,
  "lon": 0.18582
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 2
Before
2007-11
After
2008-01
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2007-12-12
After
2008-01-22
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2007-12-17
After
2008-01-24
Sponsor and administrative fields Sponsor, collaborator, oversight, or registry maintenance changes. Triage: Uncategorized 3 ops
replace /protocolSection/identificationModule/briefTitle
Triage: Uncategorized
Uncategorized Operation 1
Before
ALTTO(Adjuvant Lapatinib and/or Trastuzumab Treatment Optimisation)Study; BIG 2-06 / N063D
After
ALTTO(Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation)Study; BIG 2-06/N063D
remove /protocolSection/sponsorCollaboratorsModule/collaborators/1
Triage: Uncategorized
Uncategorized Operation 5
Before
{
  "name": "National Cancer Institute (NCI)",
  "class": "NIH"
}
remove /protocolSection/sponsorCollaboratorsModule/collaborators/1
Triage: Uncategorized
Uncategorized Operation 6
Before
{
  "name": "Breast International Group",
  "class": "OTHER"
}
Raw JSON Patch
[
  {
    "op": "replace",
    "path": "/protocolSection/identificationModule/briefTitle",
    "value": "ALTTO(Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation)Study; BIG 2-06/N063D"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2008-01"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2008-01-22"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2008-01-24"
  },
  {
    "op": "remove",
    "path": "/protocolSection/sponsorCollaboratorsModule/collaborators/1"
  },
  {
    "op": "remove",
    "path": "/protocolSection/sponsorCollaboratorsModule/collaborators/1"
  },
  {
    "op": "remove",
    "path": "/protocolSection/outcomesModule/primaryOutcomes/0/timeFrame"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/0",
    "value": {
      "zip": "33916",
      "city": "Fort Myers",
      "state": "Florida",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Thomas Ervin",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Center",
      "geoPoint": {
        "lat": 26.62168,
        "lon": -81.84059
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/1",
    "value": {
      "zip": "45242",
      "city": "Cincinnati",
      "state": "Ohio",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Patrick Ward",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinial Trials Call Center",
      "geoPoint": {
        "lat": 39.12711,
        "lon": -84.51439
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/2",
    "value": {
      "zip": "37404",
      "city": "Chattanooga",
      "state": "Tennessee",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Brooke Daniel",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Center",
      "geoPoint": {
        "lat": 35.04563,
        "lon": -85.30968
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/3",
    "value": {
      "zip": "37203",
      "city": "Nashville",
      "state": "Tennessee",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Denise Yardley",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Center",
      "geoPoint": {
        "lat": 36.16589,
        "lon": -86.78444
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/4",
    "value": {
      "zip": "23230",
      "city": "Richmond",
      "state": "Virginia",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "David Trent",
          "role": "CONTACT",
          "phone": "877-379-3718"
        }
      ],
      "facility": "GSK Clinical Trials Call Center",
      "geoPoint": {
        "lat": 37.55376,
        "lon": -77.46026
      }
    }
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/6/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/46/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/48/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/50/status",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/52/status",
    "value": "RECRUITING"
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