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NCT00530868

Comparing Letrozole Given Alone to Letrozole Given With Avastin in Post-Menopausal Women Breast Cancer

Version 11 to 12 · University of Alabama at Birmingham

Patch inspector

Version 11 to 12

31 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:58:46+00
Raw hash
9f63a99bbc3c60392c30dade902a3af347b0658d1640f960fce5052f016ef4d1
Payload
Source URL
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 27 ops
remove /protocolSection/contactsLocationsModule/centralContacts
Triage: Low
Administrative Contact Change Operation 5
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
[
  {
    "name": "Alma Del Grosso, RN, BSN, OCN",
    "role": "CONTACT",
    "email": "Alma.DelGrosso@ccc.uab.edu",
    "phone": "(205) 934-0337"
  },
  {
    "name": "Pam Dixon, RN, OCN, CCRP",
    "role": "CONTACT",
    "email": "Pam.Dixon@ccc.uab.edu",
    "phone": "(205) 975-5387"
  }
]
remove /protocolSection/contactsLocationsModule/locations/0/status
Triage: Uncategorized
Uncategorized Operation 6
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/0/contacts
Triage: Uncategorized
Uncategorized Operation 7
Before
[
  {
    "name": "Andres Forero, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  },
  {
    "name": "Lisle Nabell, M.D.",
    "role": "SUB_INVESTIGATOR"
  },
  {
    "name": "John Carpenter, M.D.",
    "role": "SUB_INVESTIGATOR"
  },
  {
    "name": "Carla Falkson, M.D.",
    "role": "SUB_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/1/status
Triage: Uncategorized
Uncategorized Operation 8
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/1/contacts
Triage: Uncategorized
Uncategorized Operation 9
Before
[
  {
    "name": "Michael Pelayo",
    "role": "CONTACT",
    "email": "pelayom@cc.ucsf.edu",
    "phone": "415-885-3789"
  },
  {
    "name": "Hope Rugo, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/2/status
Triage: Uncategorized
Uncategorized Operation 10
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/2/contacts
Triage: Uncategorized
Uncategorized Operation 11
Before
[
  {
    "name": "Minetta Liu, M.D.",
    "role": "CONTACT",
    "phone": "202-444-3677"
  }
]
remove /protocolSection/contactsLocationsModule/locations/3/status
Triage: Uncategorized
Uncategorized Operation 12
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/3/contacts
Triage: Uncategorized
Uncategorized Operation 13
Before
[
  {
    "name": "Mansoor Saleh, M.D.",
    "role": "CONTACT",
    "email": "Mansoor.Saleh@gacancer.com",
    "phone": "404-256-4777"
  },
  {
    "name": "Mansoor Saleh, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/4/status
Triage: Uncategorized
Uncategorized Operation 14
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/4/contacts
Triage: Uncategorized
Uncategorized Operation 15
Before
[
  {
    "name": "Rita Nanda, MD",
    "role": "CONTACT",
    "phone": "773-834-2756"
  },
  {
    "name": "Rita Nanda, MD",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
replace /protocolSection/contactsLocationsModule/locations/5/facility
Triage: Uncategorized
Uncategorized Operation 16
Before
Indiana University
After
Dana Farber Cancer Institute
remove /protocolSection/contactsLocationsModule/locations/5/status
Triage: Uncategorized
Uncategorized Operation 17
Before
WITHDRAWN
replace /protocolSection/contactsLocationsModule/locations/5/city
Triage: Uncategorized
Uncategorized Operation 18
Before
Indianapolis
After
Boston
replace /protocolSection/contactsLocationsModule/locations/5/state
Triage: Uncategorized
Uncategorized Operation 19
Before
Indiana
After
Massachusetts
replace /protocolSection/contactsLocationsModule/locations/5/zip
Triage: Uncategorized
Uncategorized Operation 20
Before
46202
After
02115
replace /protocolSection/contactsLocationsModule/locations/5/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 21
Before
39.76838
After
42.35843
replace /protocolSection/contactsLocationsModule/locations/5/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 22
Before
-86.15804
After
-71.05977
replace /protocolSection/contactsLocationsModule/locations/6/facility
Triage: Uncategorized
Uncategorized Operation 23
Before
Dana Farber Cancer Institute
After
University of of North Carolina at Chapel Hill
remove /protocolSection/contactsLocationsModule/locations/6/status
Triage: Uncategorized
Uncategorized Operation 24
Before
RECRUITING
replace /protocolSection/contactsLocationsModule/locations/6/city
Triage: Uncategorized
Uncategorized Operation 25
Before
Boston
After
Chapel Hill
replace /protocolSection/contactsLocationsModule/locations/6/state
Triage: Uncategorized
Uncategorized Operation 26
Before
Massachusetts
After
North Carolina
replace /protocolSection/contactsLocationsModule/locations/6/zip
Triage: Uncategorized
Uncategorized Operation 27
Before
02115
After
27599-7600
remove /protocolSection/contactsLocationsModule/locations/6/contacts
Triage: Uncategorized
Uncategorized Operation 28
Before
[
  {
    "name": "Nicole Ryabin",
    "role": "CONTACT",
    "email": "nryabin@partners.org",
    "phone": "617-632-6767"
  },
  {
    "name": "Nancy Lin, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
replace /protocolSection/contactsLocationsModule/locations/6/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 29
Before
42.35843
After
35.9132
replace /protocolSection/contactsLocationsModule/locations/6/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 30
Before
-71.05977
After
-79.05584
remove /protocolSection/contactsLocationsModule/locations/7
Triage: Uncategorized
Uncategorized Operation 31
Before
{
  "zip": "27599-7600",
  "city": "Chapel Hill",
  "state": "North Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Maureen Beeler, RN, BSN",
      "role": "CONTACT",
      "email": "maureen_beeler@med.unc.edu",
      "phone": "919-966-4432"
    },
    {
      "name": "Lisa Carey, M.D.",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "University of of North Carolina at Chapel Hill",
  "geoPoint": {
    "lat": 35.9132,
    "lon": -79.05584
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2010-11
After
2011-06
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2010-11-15
After
2011-06-14
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2010-11-16
After
2011-06-16
Status and stopping reason Recruitment status, termination, suspension, withdrawal, or why-stopped text. Triage: Uncategorized 1 ops
replace /protocolSection/statusModule/overallStatus
Triage: Uncategorized
Uncategorized Operation 2
Before
RECRUITING
After
ACTIVE_NOT_RECRUITING
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2011-06"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/overallStatus",
    "value": "ACTIVE_NOT_RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2011-06-14"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2011-06-16"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/centralContacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/1/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/1/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/2/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/2/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/3/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/3/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/4/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/4/contacts"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/5/facility",
    "value": "Dana Farber Cancer Institute"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/5/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/5/city",
    "value": "Boston"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/5/state",
    "value": "Massachusetts"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/5/zip",
    "value": "02115"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/5/geoPoint/lat",
    "value": 42.35843
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/5/geoPoint/lon",
    "value": -71.05977
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/6/facility",
    "value": "University of of North Carolina at Chapel Hill"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/6/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/6/city",
    "value": "Chapel Hill"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/6/state",
    "value": "North Carolina"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/6/zip",
    "value": "27599-7600"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/6/contacts"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/6/geoPoint/lat",
    "value": 35.9132
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/6/geoPoint/lon",
    "value": -79.05584
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/7"
  }
]