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NCT00769379

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

Version 1646 to 1647 · National Cancer Institute (NCI)

Patch inspector

Version 1646 to 1647

15 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "signal": "timeline_major_slip",
    "category": "timeline_major_slip",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "high",
    "direction": "later",
    "new_value": "2026-03-18",
    "old_value": "2025-03-07",
    "delta_days": 376,
    "date_struct": "completionDateStruct",
    "new_precision": "day",
    "old_precision": "day"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:57:20+00
Raw hash
45176c822fb4eb47c7ec1d82296980ab4551e0835ebd43b540ab7562195e1928
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 1 ops
replace /protocolSection/statusModule/completionDateStruct/date
Triage: Medium
Timeline Shift Operation 1
Matched rules
  • completion_timeline_change Completion date changes are operational timeline signals.
Before
2025-03-07
After
2026-03-18
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 12 ops
replace /protocolSection/contactsLocationsModule/locations/156/facility
Triage: Uncategorized
Uncategorized Operation 4
Before
Littleton Adventist Hospital
After
AdventHealth Littleton
replace /protocolSection/contactsLocationsModule/locations/163/facility
Triage: Uncategorized
Uncategorized Operation 5
Before
Parker Adventist Hospital
After
AdventHealth Parker
replace /protocolSection/contactsLocationsModule/locations/386/facility
Triage: Uncategorized
Uncategorized Operation 6
Before
Mission Cancer and Blood - West Des Moines
After
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
replace /protocolSection/contactsLocationsModule/locations/388/facility
Triage: Uncategorized
Uncategorized Operation 7
Before
Genesis Medical Center - East Campus
After
MercyOne Genesis Davenport Medical Center
replace /protocolSection/contactsLocationsModule/locations/392/facility
Triage: Uncategorized
Uncategorized Operation 8
Before
Mission Cancer and Blood - Des Moines
After
UI Health Care Mission Cancer and Blood - Des Moines Clinic
replace /protocolSection/contactsLocationsModule/locations/394/facility
Triage: Uncategorized
Uncategorized Operation 9
Before
Mission Cancer and Blood - Laurel
After
UI Health Care Mission Cancer and Blood - Laurel Clinic
replace /protocolSection/contactsLocationsModule/locations/430/facility
Triage: Uncategorized
Uncategorized Operation 10
Before
Ascension Via Christi - Pittsburg
After
Mercy Hospital Pittsburg
replace /protocolSection/contactsLocationsModule/locations/435/facility
Triage: Uncategorized
Uncategorized Operation 11
Before
Advent Health - Shawnee Mission Medical Center
After
AdventHealth Shawnee Mission
add /protocolSection/contactsLocationsModule/locations/611
Triage: Uncategorized
Uncategorized Operation 12
After
{
  "zip": "63703",
  "city": "Cape Girardeau",
  "state": "Missouri",
  "country": "United States",
  "facility": "Mercy Cancer Center - Cape Girardeau",
  "geoPoint": {
    "lat": 37.30588,
    "lon": -89.51815
  }
}
remove /protocolSection/contactsLocationsModule/locations/613
Triage: Uncategorized
Uncategorized Operation 13
Before
{
  "zip": "63703",
  "city": "Cape Girardeau",
  "state": "Missouri",
  "country": "United States",
  "facility": "Southeast Cancer Center",
  "geoPoint": {
    "lat": 37.30588,
    "lon": -89.51815
  }
}
remove /protocolSection/contactsLocationsModule/locations/632
Triage: Uncategorized
Uncategorized Operation 14
Before
{
  "zip": "65401",
  "city": "Rolla",
  "state": "Missouri",
  "country": "United States",
  "facility": "Delbert Day Cancer Institute at PCRMC",
  "geoPoint": {
    "lat": 37.95143,
    "lon": -91.77127
  }
}
add /protocolSection/contactsLocationsModule/locations/633
Triage: Uncategorized
Uncategorized Operation 15
After
{
  "zip": "65401",
  "city": "Rolla",
  "state": "Missouri",
  "country": "United States",
  "facility": "Phelps Health Delbert Day Cancer Institute",
  "geoPoint": {
    "lat": 37.95143,
    "lon": -91.77127
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 2 ops
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 2
Before
2025-03-14
After
2025-03-28
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 3
Before
2025-03-17
After
2025-04-11
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "value": "2026-03-18"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2025-03-28"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2025-04-11"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/156/facility",
    "value": "AdventHealth Littleton"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/163/facility",
    "value": "AdventHealth Parker"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/386/facility",
    "value": "UI Health Care Mission Cancer and Blood - West Des Moines Clinic"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/388/facility",
    "value": "MercyOne Genesis Davenport Medical Center"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/392/facility",
    "value": "UI Health Care Mission Cancer and Blood - Des Moines Clinic"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/394/facility",
    "value": "UI Health Care Mission Cancer and Blood - Laurel Clinic"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/430/facility",
    "value": "Mercy Hospital Pittsburg"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/435/facility",
    "value": "AdventHealth Shawnee Mission"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/611",
    "value": {
      "zip": "63703",
      "city": "Cape Girardeau",
      "state": "Missouri",
      "country": "United States",
      "facility": "Mercy Cancer Center - Cape Girardeau",
      "geoPoint": {
        "lat": 37.30588,
        "lon": -89.51815
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/613"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/632"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/633",
    "value": {
      "zip": "65401",
      "city": "Rolla",
      "state": "Missouri",
      "country": "United States",
      "facility": "Phelps Health Delbert Day Cancer Institute",
      "geoPoint": {
        "lat": 37.95143,
        "lon": -91.77127
      }
    }
  }
]