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NCT00769379

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

Version 42 to 43 · National Cancer Institute (NCI)

Patch inspector

Version 42 to 43

12 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
arms_or_interventions_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:44:55+00
Raw hash
18012b782b9a23db7c2c97107d5370fffccd869dcebb109e2268e8b2d634c80f
Payload
Source URL
Design Trial model, phase, allocation, masking, arms, or interventions. Triage: High 5 ops
replace /protocolSection/armsInterventionsModule/armGroups/0/interventionNames/0
Triage: High
Arm Intervention Change Operation 3
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
Procedure: radiation therapy
After
Radiation: radiation therapy
replace /protocolSection/armsInterventionsModule/armGroups/1/interventionNames/0
Triage: High
Arm Intervention Change Operation 4
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
Drug: trastuzumab
After
Biological: trastuzumab
replace /protocolSection/armsInterventionsModule/armGroups/1/interventionNames/1
Triage: High
Arm Intervention Change Operation 5
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
Procedure: radiation therapy
After
Radiation: radiation therapy
replace /protocolSection/armsInterventionsModule/interventions/0/type
Triage: High
Arm Intervention Change Operation 6
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
DRUG
After
BIOLOGICAL
replace /protocolSection/armsInterventionsModule/interventions/1/type
Triage: High
Arm Intervention Change Operation 7
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
PROCEDURE
After
RADIATION
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 5 ops
add /protocolSection/contactsLocationsModule/locations/34
Triage: Uncategorized
Uncategorized Operation 8
After
{
  "zip": "60631",
  "city": "Chicago",
  "state": "Illinois",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Christopher G. Rose, MD",
      "role": "CONTACT",
      "phone": "847-965-3200"
    }
  ],
  "facility": "Resurrection Medical Center",
  "geoPoint": {
    "lat": 41.85003,
    "lon": -87.65005
  }
}
remove /protocolSection/contactsLocationsModule/locations/71
Triage: Uncategorized
Uncategorized Operation 9
Before
{
  "zip": "52403",
  "city": "Cedar Rapids",
  "state": "Iowa",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Clinical Trials Office - Cedar Rapids Oncology Associates",
      "role": "CONTACT",
      "phone": "319-363-2690"
    }
  ],
  "facility": "Cedar Rapids Oncology Associates",
  "geoPoint": {
    "lat": 42.00833,
    "lon": -91.64407
  }
}
add /protocolSection/contactsLocationsModule/locations/76
Triage: Uncategorized
Uncategorized Operation 10
After
{
  "zip": "50701",
  "city": "Waterloo",
  "state": "Iowa",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Boriana S. Kamenova",
      "role": "CONTACT",
      "phone": "319-833-5907"
    }
  ],
  "facility": "Cedar Valley Medical Specialists, PC - West Ridgeway Avenue",
  "geoPoint": {
    "lat": 42.49276,
    "lon": -92.34296
  }
}
remove /protocolSection/contactsLocationsModule/locations/149
Triage: Uncategorized
Uncategorized Operation 11
Before
{
  "zip": "59715",
  "city": "Bozeman",
  "state": "Montana",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Benjamin T. Marchello, MD",
      "role": "CONTACT",
      "phone": "406-238-6290"
    }
  ],
  "facility": "Bozeman Deaconess Cancer Center",
  "geoPoint": {
    "lat": 45.67965,
    "lon": -111.03856
  }
}
add /protocolSection/contactsLocationsModule/locations/207
Triage: Uncategorized
Uncategorized Operation 12
After
{
  "zip": "05201",
  "city": "Bennington",
  "state": "Vermont",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Orion M. Howard",
      "role": "CONTACT",
      "phone": "802-442-1290"
    }
  ],
  "facility": "Green Mountain Oncology Group",
  "geoPoint": {
    "lat": 42.87813,
    "lon": -73.19677
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 2 ops
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2009-02-03
After
2009-02-04
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 2
Before
2009-02-04
After
2009-02-05
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2009-02-04"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2009-02-05"
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/armGroups/0/interventionNames/0",
    "value": "Radiation: radiation therapy"
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/armGroups/1/interventionNames/0",
    "value": "Biological: trastuzumab"
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/armGroups/1/interventionNames/1",
    "value": "Radiation: radiation therapy"
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/interventions/0/type",
    "value": "BIOLOGICAL"
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/interventions/1/type",
    "value": "RADIATION"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/34",
    "value": {
      "zip": "60631",
      "city": "Chicago",
      "state": "Illinois",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Christopher G. Rose, MD",
          "role": "CONTACT",
          "phone": "847-965-3200"
        }
      ],
      "facility": "Resurrection Medical Center",
      "geoPoint": {
        "lat": 41.85003,
        "lon": -87.65005
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/71"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/76",
    "value": {
      "zip": "50701",
      "city": "Waterloo",
      "state": "Iowa",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Boriana S. Kamenova",
          "role": "CONTACT",
          "phone": "319-833-5907"
        }
      ],
      "facility": "Cedar Valley Medical Specialists, PC - West Ridgeway Avenue",
      "geoPoint": {
        "lat": 42.49276,
        "lon": -92.34296
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/149"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/207",
    "value": {
      "zip": "05201",
      "city": "Bennington",
      "state": "Vermont",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Orion M. Howard",
          "role": "CONTACT",
          "phone": "802-442-1290"
        }
      ],
      "facility": "Green Mountain Oncology Group",
      "geoPoint": {
        "lat": 42.87813,
        "lon": -73.19677
      }
    }
  }
]