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NCT00769379

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

Version 499 to 500 · National Cancer Institute (NCI)

Patch inspector

Version 499 to 500

12 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_major_slip",
    "category": "timeline_major_slip",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "later",
    "new_value": "2019-03",
    "old_value": "2011-08",
    "delta_days": 2769,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "month",
    "old_precision": "month"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:48:20+00
Raw hash
2b8aa3cee8fc8bbcfbe06ccffc10d4f2b079e10ef7f60449d625575247dac3a2
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 1 ops
replace /protocolSection/statusModule/primaryCompletionDateStruct/date
Triage: Medium
Timeline Shift Operation 2
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
2011-08
After
2019-03
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 8 ops
add /protocolSection/contactsLocationsModule/locations/24
Triage: Uncategorized
Uncategorized Operation 5
After
{
  "zip": "93720",
  "city": "Fresno",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Louis Fehrenbacher, MD",
      "role": "CONTACT",
      "phone": "707-651-2577"
    }
  ],
  "facility": "Kaiser Permanente Fresno Medical Center",
  "geoPoint": {
    "lat": 36.74773,
    "lon": -119.77237
  }
}
add /protocolSection/contactsLocationsModule/locations/452
Triage: Uncategorized
Uncategorized Operation 6
After
{
  "zip": "88011",
  "city": "Las Cruces",
  "state": "New Mexico",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Melanie E. Royce, MD, PhD",
      "role": "CONTACT",
      "phone": "505-272-6057"
    }
  ],
  "facility": "University of New Mexico Cancer Center - South",
  "geoPoint": {
    "lat": 32.31232,
    "lon": -106.77834
  }
}
add /protocolSection/contactsLocationsModule/locations/472
Triage: Uncategorized
Uncategorized Operation 7
After
{
  "zip": "10310-1699",
  "city": "Staten Island",
  "state": "New York",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Clinical Trials Office - Richmond University Medical Center",
      "role": "CONTACT",
      "phone": "718-818-2952"
    }
  ],
  "facility": "Richmond University Medical Center",
  "geoPoint": {
    "lat": 40.56233,
    "lon": -74.13986
  }
}
add /protocolSection/contactsLocationsModule/locations/503
Triage: Uncategorized
Uncategorized Operation 8
After
{
  "zip": "45267",
  "city": "Cincinnati",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Elizabeth Shaughnessy, MD",
      "role": "CONTACT",
      "phone": "513-584-8900"
    }
  ],
  "facility": "Charles M. Barrett Cancer Center at University Hospital",
  "geoPoint": {
    "lat": 39.12711,
    "lon": -84.51439
  }
}
remove /protocolSection/contactsLocationsModule/locations/560
Triage: Uncategorized
Uncategorized Operation 9
Before
{
  "zip": "97216",
  "city": "Portland",
  "state": "Oregon",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Janet C. Ruzich",
      "role": "CONTACT",
      "phone": "503-257-2500"
    }
  ],
  "facility": "Adventist Medical Center",
  "geoPoint": {
    "lat": 45.52345,
    "lon": -122.67621
  }
}
add /protocolSection/contactsLocationsModule/locations/586
Triage: Uncategorized
Uncategorized Operation 10
After
{
  "zip": "19107",
  "city": "Philadelphia",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Bernard A. Mason, MD",
      "role": "CONTACT",
      "phone": "215-829-6088"
    }
  ],
  "facility": "Joan Karnell Cancer Center at Pennsylvania Hospital",
  "geoPoint": {
    "lat": 39.95238,
    "lon": -75.16362
  }
}
add /protocolSection/contactsLocationsModule/locations/645
Triage: Uncategorized
Uncategorized Operation 11
After
{
  "zip": "22908",
  "city": "Charlottesville",
  "state": "Virginia",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Monica M.R. Morris",
      "role": "CONTACT",
      "phone": "434-924-9333"
    }
  ],
  "facility": "University of Virginia Cancer Center",
  "geoPoint": {
    "lat": 38.02931,
    "lon": -78.47668
  }
}
remove /protocolSection/contactsLocationsModule/locations/727
Triage: Uncategorized
Uncategorized Operation 12
Before
{
  "zip": "00936",
  "city": "San Juan",
  "status": "RECRUITING",
  "country": "Puerto Rico",
  "contacts": [
    {
      "name": "Luis Baez-Diaz, MD, FACP",
      "role": "CONTACT",
      "phone": "787-641-3693"
    }
  ],
  "facility": "San Juan City Hospital",
  "geoPoint": {
    "lat": 18.46633,
    "lon": -66.10572
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2011-08
After
2011-09
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2011-08-31
After
2011-09-07
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2011-09-01
After
2011-09-08
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2011-09"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2019-03"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2011-09-07"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2011-09-08"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/24",
    "value": {
      "zip": "93720",
      "city": "Fresno",
      "state": "California",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Louis Fehrenbacher, MD",
          "role": "CONTACT",
          "phone": "707-651-2577"
        }
      ],
      "facility": "Kaiser Permanente Fresno Medical Center",
      "geoPoint": {
        "lat": 36.74773,
        "lon": -119.77237
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/452",
    "value": {
      "zip": "88011",
      "city": "Las Cruces",
      "state": "New Mexico",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Melanie E. Royce, MD, PhD",
          "role": "CONTACT",
          "phone": "505-272-6057"
        }
      ],
      "facility": "University of New Mexico Cancer Center - South",
      "geoPoint": {
        "lat": 32.31232,
        "lon": -106.77834
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/472",
    "value": {
      "zip": "10310-1699",
      "city": "Staten Island",
      "state": "New York",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Clinical Trials Office - Richmond University Medical Center",
          "role": "CONTACT",
          "phone": "718-818-2952"
        }
      ],
      "facility": "Richmond University Medical Center",
      "geoPoint": {
        "lat": 40.56233,
        "lon": -74.13986
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/503",
    "value": {
      "zip": "45267",
      "city": "Cincinnati",
      "state": "Ohio",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Elizabeth Shaughnessy, MD",
          "role": "CONTACT",
          "phone": "513-584-8900"
        }
      ],
      "facility": "Charles M. Barrett Cancer Center at University Hospital",
      "geoPoint": {
        "lat": 39.12711,
        "lon": -84.51439
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/560"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/586",
    "value": {
      "zip": "19107",
      "city": "Philadelphia",
      "state": "Pennsylvania",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Bernard A. Mason, MD",
          "role": "CONTACT",
          "phone": "215-829-6088"
        }
      ],
      "facility": "Joan Karnell Cancer Center at Pennsylvania Hospital",
      "geoPoint": {
        "lat": 39.95238,
        "lon": -75.16362
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/645",
    "value": {
      "zip": "22908",
      "city": "Charlottesville",
      "state": "Virginia",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Monica M.R. Morris",
          "role": "CONTACT",
          "phone": "434-924-9333"
        }
      ],
      "facility": "University of Virginia Cancer Center",
      "geoPoint": {
        "lat": 38.02931,
        "lon": -78.47668
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/727"
  }
]