NCT01142401

Fulvestrant With or Without Bortezomib in Patients With Inoperable Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer

Version 49 to 50 · National Cancer Institute (NCI)

Patch inspector

Version 49 to 50

5 operations 2 path groups ctgov_internal_history

Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.

Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals

[
  {
    "path": "/protocolSection/statusModule/startDateStruct/date",
    "signal": "timeline_minor_adjustment",
    "category": "timeline_minor_adjustment",
    "new_type": "ACTUAL",
    "old_type": null,
    "severity": "low",
    "direction": "later",
    "new_value": "2010-05-26",
    "old_value": "2010-05",
    "delta_days": 25,
    "date_struct": "startDateStruct",
    "new_precision": "day",
    "old_precision": "month"
  },
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_minor_adjustment",
    "category": "timeline_minor_adjustment",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "low",
    "direction": "same",
    "new_value": "2017-06-01",
    "old_value": "2017-06",
    "delta_days": 0,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "day",
    "old_precision": "month"
  }
]

Provenance

Source: ctgov_internal_history
Fetched: 2026-06-18 19:13:19+00
Raw hash: 7522cd9b851f0018d316091fdb7d99d13ca931d87dcea8f5d21ad6b8db1b4ac4
Payload: Source URL

Timeline Start, primary completion, and completion date movement. Triage: Medium 3 ops

replace /protocolSection/statusModule/startDateStruct/date

Triage: Medium

Timeline Shift Operation 1

Matched rules

start_timeline_change Start date changes are operational timeline signals.

Before

2010-05

After

2010-05-26

add /protocolSection/statusModule/startDateStruct/type

Triage: Medium

Timeline Shift Operation 2

Matched rules

start_timeline_change Start date changes are operational timeline signals.

After

ACTUAL

replace /protocolSection/statusModule/primaryCompletionDateStruct/date

Triage: Medium

Timeline Shift Operation 3

Matched rules

primary_completion_timeline_change Primary completion date changes are operational timeline signals.

Before

2017-06

After

2017-06-01

Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 2 ops

replace /protocolSection/statusModule/lastUpdateSubmitDate

Triage: Uncategorized

Uncategorized Operation 4

Before

2017-05-11

After

2017-05-23

replace /protocolSection/statusModule/lastUpdatePostDateStruct/date

Triage: Uncategorized

Uncategorized Operation 5

Before

2017-05-12

After

2017-05-24

Raw JSON Patch

[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/startDateStruct/date",
    "value": "2010-05-26"
  },
  {
    "op": "add",
    "path": "/protocolSection/statusModule/startDateStruct/type",
    "value": "ACTUAL"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2017-06-01"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2017-05-23"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2017-05-24"
  }
]