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NCT01147016

Targeted T Cells After Neoadjuvant Chemotherapy in Treating Women With Stage II or III Breast Cancer Undergoing Surgery

Version 16 to 17 · Barbara Ann Karmanos Cancer Institute

Patch inspector

Version 16 to 17

7 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
enrollment_count_changeenrollment_type_changewhy_stopped_change
Value signals
[
  {
    "path": "/protocolSection/statusModule/whyStopped",
    "signal": "why_stopped_empty",
    "category": "status_termination",
    "severity": "critical"
  },
  {
    "path": "/protocolSection/designModule/enrollmentInfo/count",
    "signal": "enrollment_count_change_ge_20pct",
    "category": "enrollment_change",
    "severity": "high",
    "new_value": 8,
    "old_value": 32,
    "pct_change": 0.75
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:13:30+00
Raw hash
733e8ad5bf9f2e452ef060a199a26fd3650e7a6b1e58da35d88869c40af810f6
Payload
Source URL
Design Trial model, phase, allocation, masking, arms, or interventions. Triage: High 2 ops
replace /protocolSection/designModule/enrollmentInfo/count
Triage: High
Enrollment Change Operation 6
Matched rules
  • enrollment_count_change Enrollment count changes can signal scope or feasibility shifts.
Before
32
After
8
replace /protocolSection/designModule/enrollmentInfo/type
Triage: High
Enrollment Change Operation 7
Matched rules
  • enrollment_type_change Enrollment type changes from anticipated to actual or similar are high review priority.
Before
ESTIMATED
After
ACTUAL
Status and stopping reason Recruitment status, termination, suspension, withdrawal, or why-stopped text. Triage: High 2 ops
replace /protocolSection/statusModule/overallStatus
Triage: Uncategorized
Uncategorized Operation 2
Before
SUSPENDED
After
ACTIVE_NOT_RECRUITING
remove /protocolSection/statusModule/whyStopped
Triage: High
Status Termination Operation 3
Matched rules
  • why_stopped_change Why-stopped changes explain discontinuation and need review.
Before
Primary co-investigator leaving the institution & funding transfer.
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2016-07
After
2016-12
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 4
Before
2016-07-18
After
2016-12-05
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 5
Before
2016-07-20
After
2016-12-07
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2016-12"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/overallStatus",
    "value": "ACTIVE_NOT_RECRUITING"
  },
  {
    "op": "remove",
    "path": "/protocolSection/statusModule/whyStopped"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2016-12-05"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2016-12-07"
  },
  {
    "op": "replace",
    "path": "/protocolSection/designModule/enrollmentInfo/count",
    "value": 8
  },
  {
    "op": "replace",
    "path": "/protocolSection/designModule/enrollmentInfo/type",
    "value": "ACTUAL"
  }
]