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NCT01275677

Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer

Version 774 to 775 · National Cancer Institute (NCI)

Patch inspector

Version 774 to 775

28 operations 4 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_significant_shift",
    "category": "timeline_significant_shift",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "later",
    "new_value": "2017-08",
    "old_value": "2017-01",
    "delta_days": 212,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "month",
    "old_precision": "month"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:08:52+00
Raw hash
672adb26471ddb3bb47ab54897d9f9339415d261de55039c5bf7b41f0eec94e6
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 1 ops
replace /protocolSection/statusModule/primaryCompletionDateStruct/date
Triage: Medium
Timeline Shift Operation 3
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
2017-01
After
2017-08
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 22 ops
replace /protocolSection/contactsLocationsModule/locations/308/facility
Triage: Uncategorized
Uncategorized Operation 7
Before
Community Hospital East
After
Community Cancer Center East
replace /protocolSection/contactsLocationsModule/locations/309/facility
Triage: Uncategorized
Uncategorized Operation 8
Before
Community Regional Cancer Care-North
After
Community Cancer Center North
replace /protocolSection/contactsLocationsModule/locations/426/facility
Triage: Uncategorized
Uncategorized Operation 9
Before
Harbor Hospital Center
After
MedStar Harbor Hospital
remove /protocolSection/contactsLocationsModule/locations/451
Triage: Uncategorized
Uncategorized Operation 10
Before
{
  "zip": "02115",
  "city": "Boston",
  "state": "Massachusetts",
  "country": "United States",
  "facility": "Dana-Farber Cancer Institute",
  "geoPoint": {
    "lat": 42.35843,
    "lon": -71.05977
  }
}
add /protocolSection/contactsLocationsModule/locations/452
Triage: Uncategorized
Uncategorized Operation 11
After
{
  "zip": "02215",
  "city": "Boston",
  "state": "Massachusetts",
  "country": "United States",
  "facility": "Dana-Farber Cancer Institute",
  "geoPoint": {
    "lat": 42.35843,
    "lon": -71.05977
  }
}
replace /protocolSection/contactsLocationsModule/locations/475/city
Triage: Uncategorized
Uncategorized Operation 12
Before
Clinton Township
After
Clinton
replace /protocolSection/contactsLocationsModule/locations/475/geoPoint/lat
Triage: Uncategorized
Uncategorized Operation 13
Before
42.58698
After
42.07199
replace /protocolSection/contactsLocationsModule/locations/475/geoPoint/lon
Triage: Uncategorized
Uncategorized Operation 14
Before
-82.91992
After
-83.97161
remove /protocolSection/contactsLocationsModule/locations/598
Triage: Uncategorized
Uncategorized Operation 15
Before
{
  "zip": "59101",
  "city": "Billings",
  "state": "Montana",
  "country": "United States",
  "facility": "Montana Cancer Consortium NCORP",
  "geoPoint": {
    "lat": 45.78329,
    "lon": -108.50069
  }
}
add /protocolSection/contactsLocationsModule/locations/600
Triage: Uncategorized
Uncategorized Operation 16
After
{
  "zip": "59102",
  "city": "Billings",
  "state": "Montana",
  "country": "United States",
  "facility": "Montana Cancer Consortium NCORP",
  "geoPoint": {
    "lat": 45.78329,
    "lon": -108.50069
  }
}
add /protocolSection/contactsLocationsModule/locations/790
Triage: Uncategorized
Uncategorized Operation 17
After
{
  "zip": "28625",
  "city": "Statesville",
  "state": "North Carolina",
  "country": "United States",
  "facility": "Novant Health Oncology Specialists-Statesville",
  "geoPoint": {
    "lat": 35.78264,
    "lon": -80.8873
  }
}
remove /protocolSection/contactsLocationsModule/locations/792
Triage: Uncategorized
Uncategorized Operation 18
Before
{
  "zip": "28625",
  "city": "Stateville",
  "state": "North Carolina",
  "country": "United States",
  "facility": "Novant Health Oncology Specialists-Statesville"
}
replace /protocolSection/contactsLocationsModule/locations/902/city
Triage: Uncategorized
Uncategorized Operation 19
Before
Wpafb
After
Wright-Patterson Air Force Base
add /protocolSection/contactsLocationsModule/locations/902/geoPoint
Triage: Uncategorized
Uncategorized Operation 20
After
{
  "lat": 39.81791,
  "lon": -84.04995
}
replace /protocolSection/contactsLocationsModule/locations/963/facility
Triage: Uncategorized
Uncategorized Operation 21
Before
Albert Einstein Medical Center
After
Einstein Medical Center Philadelphia
replace /protocolSection/contactsLocationsModule/locations/1087/zip
Triage: Uncategorized
Uncategorized Operation 22
Before
84157
After
84107
replace /protocolSection/contactsLocationsModule/locations/1188/facility
Triage: Uncategorized
Uncategorized Operation 23
Before
HSHS Saint Vincent Hospital Regional Cancer Center
After
Saint Vincent Hospital Cancer Center Green Bay
replace /protocolSection/contactsLocationsModule/locations/1190/facility
Triage: Uncategorized
Uncategorized Operation 24
Before
Saint Mary's Hospital
After
Saint Vincent Hospital Cancer Center at Saint Mary's
replace /protocolSection/contactsLocationsModule/locations/1215/facility
Triage: Uncategorized
Uncategorized Operation 25
Before
Saint Nicholas Hospital
After
HSHS Saint Nicholas Hospital
remove /protocolSection/contactsLocationsModule/locations/1236
Triage: Uncategorized
Uncategorized Operation 26
Before
{
  "zip": "H3A 1A1",
  "city": "Montreal",
  "state": "Quebec",
  "country": "Canada",
  "facility": "Royal Victoria Hospital",
  "geoPoint": {
    "lat": 45.50884,
    "lon": -73.58781
  }
}
add /protocolSection/contactsLocationsModule/locations/1237
Triage: Uncategorized
Uncategorized Operation 27
After
{
  "zip": "H3H 2R9",
  "city": "Montreal",
  "state": "Quebec",
  "country": "Canada",
  "facility": "The Research Institute of the McGill University Health Centre (MUHC)",
  "geoPoint": {
    "lat": 45.50884,
    "lon": -73.58781
  }
}
replace /protocolSection/contactsLocationsModule/locations/1250/facility
Triage: Uncategorized
Uncategorized Operation 28
Before
Sligo General Hospital
After
Sligo University Hospital
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 4 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 2
Before
2017-01
After
2017-05
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 4
Before
2017-01-31
After
2017-05-03
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 5
Before
2017-02-01
After
2017-05-04
replace /protocolSection/statusModule/lastUpdatePostDateStruct/type
Triage: Uncategorized
Uncategorized Operation 6
Before
ESTIMATED
After
ACTUAL
Sponsor and administrative fields Sponsor, collaborator, oversight, or registry maintenance changes. Triage: Uncategorized 1 ops
add /protocolSection/identificationModule/secondaryIdInfos/1
Triage: Uncategorized
Uncategorized Operation 1
After
{
  "id": "NSABP-B-47"
}
Raw JSON Patch 
[
  {
    "op": "add",
    "path": "/protocolSection/identificationModule/secondaryIdInfos/1",
    "value": {
      "id": "NSABP-B-47"
    }
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2017-05"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2017-08"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2017-05-03"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2017-05-04"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/type",
    "value": "ACTUAL"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/308/facility",
    "value": "Community Cancer Center East"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/309/facility",
    "value": "Community Cancer Center North"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/426/facility",
    "value": "MedStar Harbor Hospital"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/451"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/452",
    "value": {
      "zip": "02215",
      "city": "Boston",
      "state": "Massachusetts",
      "country": "United States",
      "facility": "Dana-Farber Cancer Institute",
      "geoPoint": {
        "lat": 42.35843,
        "lon": -71.05977
      }
    }
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/475/city",
    "value": "Clinton"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/475/geoPoint/lat",
    "value": 42.07199
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/475/geoPoint/lon",
    "value": -83.97161
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/598"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/600",
    "value": {
      "zip": "59102",
      "city": "Billings",
      "state": "Montana",
      "country": "United States",
      "facility": "Montana Cancer Consortium NCORP",
      "geoPoint": {
        "lat": 45.78329,
        "lon": -108.50069
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/790",
    "value": {
      "zip": "28625",
      "city": "Statesville",
      "state": "North Carolina",
      "country": "United States",
      "facility": "Novant Health Oncology Specialists-Statesville",
      "geoPoint": {
        "lat": 35.78264,
        "lon": -80.8873
      }
    }
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/792"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/902/city",
    "value": "Wright-Patterson Air Force Base"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/902/geoPoint",
    "value": {
      "lat": 39.81791,
      "lon": -84.04995
    }
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/963/facility",
    "value": "Einstein Medical Center Philadelphia"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/1087/zip",
    "value": "84107"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/1188/facility",
    "value": "Saint Vincent Hospital Cancer Center Green Bay"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/1190/facility",
    "value": "Saint Vincent Hospital Cancer Center at Saint Mary's"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/1215/facility",
    "value": "HSHS Saint Nicholas Hospital"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/1236"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/1237",
    "value": {
      "zip": "H3H 2R9",
      "city": "Montreal",
      "state": "Quebec",
      "country": "Canada",
      "facility": "The Research Institute of the McGill University Health Centre (MUHC)",
      "geoPoint": {
        "lat": 45.50884,
        "lon": -73.58781
      }
    }
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/1250/facility",
    "value": "Sligo University Hospital"
  }
]