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NCT01556243

Breast-Conserving Surgery and Radiation Therapy in Patients With Multiple Ipsilateral Breast Cancer

Version 13 to 14 · Alliance for Clinical Trials in Oncology

Patch inspector

Version 13 to 14

183 operations 7 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
arms_or_interventions_changedesign_info_changeeligibility_criteria_changeprimary_outcome_any_changesecondary_outcome_any_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:59:30+00
Raw hash
752959f2bbada4b11f214685b5be94226e7f0d535fe44d93211973df97095d6b
Payload
Source URL
Primary outcomes Outcome measures that define the trial's primary evidence target. Triage: Critical 1 ops
add /protocolSection/outcomesModule/primaryOutcomes/0/timeFrame
Triage: Critical
Primary Outcome Change Operation 26
Matched rules
  • primary_outcome_any_change Any add/remove/replace under primary outcome measures is critical review priority.
After
Up to 5 years post-treatment
Design Trial model, phase, allocation, masking, arms, or interventions. Triage: High 15 ops
add /protocolSection/designModule/designInfo/allocation
Triage: High
Design Change Operation 11
Matched rules
  • design_info_change Design information changes can alter allocation, masking, model, or purpose and need review.
After
NA
add /protocolSection/designModule/designInfo/interventionModel
Triage: High
Design Change Operation 12
Matched rules
  • design_info_change Design information changes can alter allocation, masking, model, or purpose and need review.
After
SINGLE_GROUP
replace /protocolSection/armsInterventionsModule/interventions/0/type
Triage: High
Arm Intervention Change Operation 13
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
GENETIC
After
PROCEDURE
replace /protocolSection/armsInterventionsModule/interventions/0/name
Triage: High
Arm Intervention Change Operation 14
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
gene expression analysis
After
therapeutic conventional surgery
add /protocolSection/armsInterventionsModule/interventions/0/armGroupLabels
Triage: High
Arm Intervention Change Operation 15
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
After
[
  "Breast conservation surgery and radiation therapy"
]
replace /protocolSection/armsInterventionsModule/interventions/1/type
Triage: High
Arm Intervention Change Operation 16
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
GENETIC
After
RADIATION
replace /protocolSection/armsInterventionsModule/interventions/1/name
Triage: High
Arm Intervention Change Operation 17
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
protein expression analysis
After
whole breast irradiation
add /protocolSection/armsInterventionsModule/interventions/1/armGroupLabels
Triage: High
Arm Intervention Change Operation 18
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
After
[
  "Breast conservation surgery and radiation therapy"
]
remove /protocolSection/armsInterventionsModule/interventions/2
Triage: High
Arm Intervention Change Operation 19
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
{
  "name": "laboratory biomarker analysis",
  "type": "OTHER"
}
remove /protocolSection/armsInterventionsModule/interventions/2
Triage: High
Arm Intervention Change Operation 20
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
{
  "name": "questionnaire administration",
  "type": "OTHER"
}
remove /protocolSection/armsInterventionsModule/interventions/2
Triage: High
Arm Intervention Change Operation 21
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
{
  "name": "adjuvant therapy",
  "type": "PROCEDURE"
}
remove /protocolSection/armsInterventionsModule/interventions/2
Triage: High
Arm Intervention Change Operation 22
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
{
  "name": "quality-of-life assessment",
  "type": "PROCEDURE"
}
remove /protocolSection/armsInterventionsModule/interventions/2
Triage: High
Arm Intervention Change Operation 23
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
{
  "name": "therapeutic conventional surgery",
  "type": "PROCEDURE"
}
remove /protocolSection/armsInterventionsModule/interventions/2
Triage: High
Arm Intervention Change Operation 24
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
Before
{
  "name": "whole breast irradiation",
  "type": "RADIATION"
}
add /protocolSection/armsInterventionsModule/armGroups
Triage: High
Arm Intervention Change Operation 25
Matched rules
  • arms_or_interventions_change Arms or interventions changes can alter treatment/comparator structure.
After
[
  {
    "type": "EXPERIMENTAL",
    "label": "Breast conservation surgery and radiation therapy",
    "description": "Patients undergo breast conserving surgery with all lesions resected to negative margins using one lumpectomy or 2-3 separate lumpectomy incisions at the discretion of the surgeon.\nPatients receive adjuvant chemotherapy and/or endocrine therapy at the discretion of the treating medical oncologist based on tumor characteristics.\nWithin 6-10 weeks after surgery or 8 weeks after completion of cytotoxic chemotherapy, patients undergo adjuvant whole breast irradiation with a boost to the lumpectomy bed of each site of disease 5 days per week for approximately 6 weeks.",
    "interventionNames": [
      "Procedure: therapeutic conventional surgery",
      "Radiation: whole breast irradiation"
    ]
  }
]
Eligibility Criteria and population definition changes. Triage: High 1 ops
replace /protocolSection/eligibilityModule/eligibilityCriteria
Triage: High
Eligibility Change Operation 32
Matched rules
  • eligibility_criteria_change Eligibility criteria changes can alter the studied population.
Before
<p>DISEASE CHARACTERISTICS:</p><ul><li><p>Upon clinical exam and pre-operative imaging by MRI and mammogram both, two or three foci of biopsy-proven breast cancer separated by ≥ 3 cm of normal breast tissue on clinical exam and preoperative imaging; foci must include at least one focus of invasive breast carcinoma with another focus of either invasive breast carcinoma or ductal carcinoma in situ (DCIS); no more than 2 quadrants with biopsy-positive breast cancer</p><ul><li>Ultrasound cannot be used to determine patient eligibility; eligibility to be determined by bilateral mammogram and MRI only</li></ul></li><li>Bilateral mammogram ≤ 60 days prior to registration</li><li>Bilateral breast MRI ≤ 45 days prior to registration</li><li><p>cN0 or cN1 disease</p><ul><li>No cNX, cN2, or cN3 disease</li></ul></li><li>Willing to provide tissue samples for correlative research purposes</li><li>Largest single focus of disease &gt; 5 cm by either mammogram or MRI or both (measurement of the largest single focus should include any satellite lesions within 1 cm of the index lesion)</li><li>No clinical or radiographic evidence of metastatic disease</li><li>No prior or current lobular carcinoma in situ (LCIS), DCIS, or invasive breast cancer in the opposite breast (i.e., bilateral disease is not allowed)</li><li>No patients with known BRCA mutations</li></ul><p>PATIENT CHARACTERISTICS:</p><ul><li>Life expectancy of at least 5 years, excluding diagnosis of breast cancer (comorbid conditions should be taken into consideration, but breast cancer diagnosis is not a consideration)</li><li>Men are excluded from this study</li><li>Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0, 1, or 2</li><li>Hemoglobin (Hgb) ≥ 8 g&#x2F;dL</li><li>Peripheral platelet count (PLT) ≥ 50,000&#x2F;mm³</li><li>Ability to complete questionnaire(s) by themselves or with assistance</li><li>Willing to return to enrolling institution for follow-up during the Active Monitoring Phase (the active treatment and observation portions) of the study</li><li>Negative serum or urine pregnancy test done ≤ 7 days prior to registration, for women of childbearing potential only</li><li><p>None of the following:</p><ul><li>Pregnant women</li><li>Nursing women</li><li>Women of childbearing potential who are unwilling to employ adequate contraception (as determined by the treating physician)</li></ul></li><li>No co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would interfere significantly with whole-breast irradiation (such as connective tissue disorders, lupus, or scleroderma)</li><li>No uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness&#x2F;social situations that would limit compliance with study requirements</li><li><p>No other active malignancy ≤ 5 years prior to registration; EXCEPTIONS: non-melanotic skin cancer or carcinoma-in-situ of the cervix</p><ul><li>If there is a history of prior malignancy, they must not be receiving other specific treatment for their cancer</li></ul></li></ul><p>PRIOR CONCURRENT THERAPY:</p><ul><li><p>No surgical axillary staging procedure prior to study entry</p><ul><li>Fine-needle aspiration (FNA) or core-needle biopsy of axillary node is permitted</li></ul></li><li><p>No breast implants at time of diagnosis</p><ul><li>Patients who have had implants previously removed prior to diagnosis are eligible</li></ul></li><li>No treatment including radiation therapy, chemotherapy, biotherapy, or hormonal therapy for this cancer prior to registration</li><li>No neoadjuvant endocrine therapy or neoadjuvant hormonal therapy</li><li>No planned partial-breast radiation</li><li>No administration of any investigational agent ≤ 30 days prior to registration</li></ul>
After
<p>Registration Inclusion Criteria:</p><ol><li>Age ≥ 40 years per National Comprehensive Cancer Network (NCCN) recommendations for breast conservation.</li><li>Life Expectancy of at least 5 years, excluding diagnosis of breast cancer (Comorbid conditions should be taken into consideration, but breast cancer diagnosis is not a consideration)</li><li><p>Female Gender - Men are excluded from this study.
Male breast cancer is a rare event.</p><p>Men are rarely candidates for breast conservation surgery due to small breast size.
Men are less likely to be candidates for breast conservation surgery if found to have MIBC.</p></li><li><p>Foci of Breast Cancer - Upon clinical exam and pre-operative imaging by both MRI and mammogram, two or three foci of biopsy proven breast cancer separated by &gt; 2 cm of normal breast tissue.
Foci must include at least one focus of invasive breast carcinoma with another focus of either invasive breast carcinoma or ductal carcinoma in situ (DCIS).</p><p>No more than 2 quadrants with biopsy proven breast cancer.</p><p>Note: Patient is eligible for study if lesion is not visualized on both imaging modalities (i.e., any of the lesion(s) is&#x2F;are visualized on MRI but not on mammogram OR visualized on mammogram but not on MRI).
Ultrasound cannot be used to determine patient eligibility; eligibility to be determined by bilateral mammogram and MRI only.
Patient may remain on study if, upon pathological assessment, two or three lesions identified on pre-operative imaging represent one contiguous lesion.</p></li><li>Mammogram Imaging - Bilateral mammogram ≤ 60 days prior to registration</li><li>MRI Imaging - Bilateral breast MRI ≤ 60 days prior to registration</li><li>Staging of Cancer - cN0 or cN1 disease</li><li><p>ECOG Performance Status (PS) - 0, 1, or 2.</p><p>Note: An ECOG PS scale is available on the Cancer Trial Support Unit (CTSU) website.</p></li><li><p>Hemoglobin and Platelet Count - The following laboratory values obtained ≤ 21 days prior to registration:</p><ul><li>Hemoglobin (Hgb) ≥ 8 g&#x2F;dL</li><li>Peripheral platelet count (PLT) ≥ 50,000&#x2F;mm3</li></ul></li><li>Pregnancy for Women of Childbearing Potential - Negative urine or serum pregnancy test result ≤ 7 days prior to registration for women of childbearing potential only.</li><li>Ability to Complete Questionnaires by themselves or with assistance.</li><li>Ability to Provide Written Informed Consent</li><li>Willing to return to enrolling institution for follow-up during the Active Monitoring Phase (the active treatment and observation portions) of the study.
Patients are encouraged to return to the enrolling institution; however, patients may receive radiation therapy at a different institution other than the enrolling institution.</li></ol><p>Registration Exclusion Criteria:</p><ol><li><p>Pregnancy, Nursing and Requirement for Contraception Any of the following because this study involves radiation therapy (WBI) that has known genotoxic, mutagenic and teratogenic effects:</p><ul><li>Pregnant women</li><li>Nursing women</li><li>Women of childbearing potential who are unwilling to employ adequate contraception (as determined by the treating physician)</li></ul></li><li>Size of Single Focus of Disease - Largest single focus of disease &gt; 5 centimeters by either mammogram or MRI or both.
Note: Measurement of the largest single focus should include any satellite lesions within 1centimeter of the index lesion.</li><li><p>Prior Staging Procedure - Surgical axillary staging procedure prior to study entry.</p><p>Note: FNA or core needle biopsy of axillary node is permitted.</p></li><li>Evidence of Metastatic Disease - Clinical or radiographic evidence of metastatic disease</li><li>Prior history of ipsilateral breast cancer [DCIS, LCIS (lobular cancer in situ) or invasive]</li><li>Staging of Cancer - cNX, cN2, or cN3 disease</li><li><p>Breast Implants at time of diagnosis.</p><p>Note: Patients who have had implants previously removed prior to diagnosis are eligible.</p></li><li>Systemic Illnesses or Concurrent Disease - Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would interfere significantly with whole breast irradiation (such as connective tissue disorders, lupus, scleroderma).</li><li>Uncontrolled Intercurrent Illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness&#x2F;social situations that would limit compliance with study requirements.</li><li>Bilateral Breast Cancer Prior or current LCIS, DCIS or invasive breast cancer in the opposite breast (i.e., bilateral disease is not allowed).</li><li>Disallowed Prior Treatments - Treatment including radiation therapy, chemotherapy, biotherapy, hormonal therapy for this cancer prior to registration.</li><li>Chemotherapy or Endocrine Therapy Prior to Surgery - Neoadjuvant chemotherapy or neoadjuvant endocrine therapy (in other words, no chemotherapy or endocrine therapy prior to surgery) for this cancer.</li><li>Partial Breast Radiation - Planned partial breast radiation.</li><li>Investigational Agents - Administration of any investigational agent ≤ 30 days prior to registration.</li><li>Known BRCA Mutations - Patients with known BRCA mutations.</li><li>Other Active Malignancies - Other active malignancy ≤ 5 years prior to registration.</li></ol><p>Exceptions: Non-melanotic skin cancer or carcinoma-in-situ of the cervix.
Note: If there is a history of prior malignancy, they must not be receiving other specific treatment for their cancer.</p>
Secondary outcomes Additional endpoints and outcome descriptions. Triage: High 5 ops
replace /protocolSection/outcomesModule/secondaryOutcomes/0/measure
Triage: High
Secondary Outcome Change Operation 27
Matched rules
  • secondary_outcome_any_change Any add/remove/replace under secondary outcome measures is high review priority.
Before
Conversion rate to mastectomy secondary to persistent positive margins assessed for up to 1 year
After
Conversion rate to mastectomy secondary to persistent positive margins assessed
add /protocolSection/outcomesModule/secondaryOutcomes/0/timeFrame
Triage: High
Secondary Outcome Change Operation 28
Matched rules
  • secondary_outcome_any_change Any add/remove/replace under secondary outcome measures is high review priority.
After
Up to 5 years post-treatment
add /protocolSection/outcomesModule/secondaryOutcomes/1/timeFrame
Triage: High
Secondary Outcome Change Operation 29
Matched rules
  • secondary_outcome_any_change Any add/remove/replace under secondary outcome measures is high review priority.
After
Up to 30 days post-treatment
add /protocolSection/outcomesModule/secondaryOutcomes/2/timeFrame
Triage: High
Secondary Outcome Change Operation 30
Matched rules
  • secondary_outcome_any_change Any add/remove/replace under secondary outcome measures is high review priority.
After
Up to 30 days post-treatment
add /protocolSection/outcomesModule/secondaryOutcomes/3/timeFrame
Triage: High
Secondary Outcome Change Operation 31
Matched rules
  • secondary_outcome_any_change Any add/remove/replace under secondary outcome measures is high review priority.
After
Up to 2 years post-treatment
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 150 ops
add /protocolSection/contactsLocationsModule/locations/0
Triage: Uncategorized
Uncategorized Operation 33
After
{
  "zip": "94546",
  "city": "Castro Valley",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "James H. Feusner, MD",
      "role": "CONTACT",
      "phone": "510-428-3689"
    }
  ],
  "facility": "East Bay Radiation Oncology Center",
  "geoPoint": {
    "lat": 37.6941,
    "lon": -122.08635
  }
}
add /protocolSection/contactsLocationsModule/locations/1
Triage: Uncategorized
Uncategorized Operation 34
After
{
  "zip": "92093",
  "city": "La Jolla",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Sarah Blair, M.D.",
      "role": "CONTACT",
      "phone": "858-822-5354"
    }
  ],
  "facility": "UC San Diego Moores Cancer Center",
  "geoPoint": {
    "lat": 32.84727,
    "lon": -117.2742
  }
}
add /protocolSection/contactsLocationsModule/locations/2
Triage: Uncategorized
Uncategorized Operation 35
After
{
  "zip": "90048",
  "city": "Los Angeles",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Armando Giuliano, M.D.",
      "role": "CONTACT",
      "phone": "310-423-9331"
    }
  ],
  "facility": "Cedars-Sinai Medical Center",
  "geoPoint": {
    "lat": 34.05223,
    "lon": -118.24368
  }
}
add /protocolSection/contactsLocationsModule/locations/5
Triage: Uncategorized
Uncategorized Operation 36
After
{
  "zip": "94609",
  "city": "Oakland",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "James Feusner, M.D.",
      "role": "CONTACT",
      "phone": "510-450-7600"
    }
  ],
  "facility": "Alta Bates Summit Medical Center - Summit Campus",
  "geoPoint": {
    "lat": 37.80437,
    "lon": -122.2708
  }
}
add /protocolSection/contactsLocationsModule/locations/10
Triage: Uncategorized
Uncategorized Operation 37
After
{
  "zip": "95661",
  "city": "Roseville",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jay Owens, M.D.",
      "role": "CONTACT",
      "phone": "916-454-6500"
    }
  ],
  "facility": "Sutter Roseville Medical Center",
  "geoPoint": {
    "lat": 38.75212,
    "lon": -121.28801
  }
}
add /protocolSection/contactsLocationsModule/locations/11
Triage: Uncategorized
Uncategorized Operation 38
After
{
  "zip": "95816",
  "city": "Sacramento",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jay Owens, M.D.",
      "role": "CONTACT",
      "phone": "916-454-6500"
    }
  ],
  "facility": "Sutter General Hospital",
  "geoPoint": {
    "lat": 38.58157,
    "lon": -121.4944
  }
}
add /protocolSection/contactsLocationsModule/locations/12
Triage: Uncategorized
Uncategorized Operation 39
After
{
  "zip": "92123",
  "city": "San Diego",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Robert M. Barone, MD, FACS",
      "role": "CONTACT",
      "phone": "858-637-7888"
    }
  ],
  "facility": "Sharp Memorial Hospital",
  "geoPoint": {
    "lat": 32.71571,
    "lon": -117.16472
  }
}
add /protocolSection/contactsLocationsModule/locations/14
Triage: Uncategorized
Uncategorized Operation 40
After
{
  "zip": "94305",
  "city": "Stanford",
  "state": "California",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Frederick Dirbas, M.D.",
      "role": "CONTACT",
      "phone": "650-498-7061"
    }
  ],
  "facility": "Stanford University Hospitals and Clinics",
  "geoPoint": {
    "lat": 37.42411,
    "lon": -122.16608
  }
}
add /protocolSection/contactsLocationsModule/locations/15
Triage: Uncategorized
Uncategorized Operation 41
After
{
  "zip": "80045",
  "city": "Aurora",
  "state": "Colorado",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Nicole Kounalakis, M.D.",
      "role": "CONTACT",
      "phone": "720-848-0650"
    }
  ],
  "facility": "University of Colorado Cancer Center - Anschutz Cancer Pavilion",
  "geoPoint": {
    "lat": 39.72943,
    "lon": -104.83192
  }
}
add /protocolSection/contactsLocationsModule/locations/16
Triage: Uncategorized
Uncategorized Operation 42
After
{
  "zip": "06606",
  "city": "Bridgeport",
  "state": "Connecticut",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Anthy Demestihas, M.D.",
      "role": "CONTACT",
      "phone": "888-823-5923"
    }
  ],
  "facility": "Saint Vincent&#x27;s Medical Center",
  "geoPoint": {
    "lat": 41.17923,
    "lon": -73.18945
  }
}
add /protocolSection/contactsLocationsModule/locations/19
Triage: Uncategorized
Uncategorized Operation 43
After
{
  "zip": "19718",
  "city": "Newark",
  "state": "Delaware",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Diana Dickson-Witmer, M.D.",
      "role": "CONTACT",
      "phone": "302-733-6227"
    }
  ],
  "facility": "Christiana Care Health System-Christiana Hospital",
  "geoPoint": {
    "lat": 39.68372,
    "lon": -75.74966
  }
}
add /protocolSection/contactsLocationsModule/locations/20
Triage: Uncategorized
Uncategorized Operation 44
After
{
  "zip": "33756",
  "city": "Clearwater",
  "state": "Florida",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Peter W. Blumencranz, MD",
      "role": "CONTACT",
      "phone": "727-462-2131"
    }
  ],
  "facility": "Morton Plant Hospital",
  "geoPoint": {
    "lat": 27.96585,
    "lon": -82.8001
  }
}
add /protocolSection/contactsLocationsModule/locations/21
Triage: Uncategorized
Uncategorized Operation 45
After
{
  "zip": "33308",
  "city": "Fort Lauderdale",
  "state": "Florida",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Michael Schwartz, M.D.",
      "role": "CONTACT",
      "phone": "305-674-2625"
    }
  ],
  "facility": "Holy Cross Hospital",
  "geoPoint": {
    "lat": 26.12231,
    "lon": -80.14338
  }
}
add /protocolSection/contactsLocationsModule/locations/22
Triage: Uncategorized
Uncategorized Operation 46
After
{
  "zip": "33458",
  "city": "Jupiter",
  "state": "Florida",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Michael Schwartz, M.D.",
      "role": "CONTACT",
      "phone": "305-674-2625"
    }
  ],
  "facility": "Jupiter Medical Center",
  "geoPoint": {
    "lat": 26.93422,
    "lon": -80.09421
  }
}
add /protocolSection/contactsLocationsModule/locations/23
Triage: Uncategorized
Uncategorized Operation 47
After
{
  "zip": "33140",
  "city": "Miami Beach",
  "state": "Florida",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Michael Schwartz, M.D.",
      "role": "CONTACT",
      "phone": "305-674-2625"
    }
  ],
  "facility": "Mount Sinai Medical Center CCOP",
  "geoPoint": {
    "lat": 25.79065,
    "lon": -80.13005
  }
}
add /protocolSection/contactsLocationsModule/locations/24
Triage: Uncategorized
Uncategorized Operation 48
After
{
  "zip": "30033",
  "city": "Decatur",
  "state": "Georgia",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Kennedy, M.D.",
      "role": "CONTACT",
      "phone": "404-501-3279"
    }
  ],
  "facility": "Dekalb Medical Center",
  "geoPoint": {
    "lat": 33.77483,
    "lon": -84.29631
  }
}
add /protocolSection/contactsLocationsModule/locations/25
Triage: Uncategorized
Uncategorized Operation 49
After
{
  "zip": "96813",
  "city": "Honolulu",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey Berenberg, M.D.",
      "role": "CONTACT",
      "phone": "808-586-2979"
    }
  ],
  "facility": "Oncare Hawaii Inc-POB II",
  "geoPoint": {
    "lat": 21.30694,
    "lon": -157.85833
  }
}
add /protocolSection/contactsLocationsModule/locations/26
Triage: Uncategorized
Uncategorized Operation 50
After
{
  "zip": "96813",
  "city": "Honolulu",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey Berenberg, M.D.",
      "role": "CONTACT",
      "phone": "808-433-4089"
    }
  ],
  "facility": "Queen&#x27;s Medical Center",
  "geoPoint": {
    "lat": 21.30694,
    "lon": -157.85833
  }
}
add /protocolSection/contactsLocationsModule/locations/27
Triage: Uncategorized
Uncategorized Operation 51
After
{
  "zip": "96813",
  "city": "Honolulu",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey L. Berenberg, MD",
      "role": "CONTACT",
      "phone": "808-433-4089"
    }
  ],
  "facility": "Straub Clinic and Hospital, Incorporated",
  "geoPoint": {
    "lat": 21.30694,
    "lon": -157.85833
  }
}
add /protocolSection/contactsLocationsModule/locations/28
Triage: Uncategorized
Uncategorized Operation 52
After
{
  "zip": "96813",
  "city": "Honolulu",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey Berenberg, M.D.",
      "role": "CONTACT",
      "phone": "808-433-4089"
    }
  ],
  "facility": "University of Hawaii",
  "geoPoint": {
    "lat": 21.30694,
    "lon": -157.85833
  }
}
add /protocolSection/contactsLocationsModule/locations/29
Triage: Uncategorized
Uncategorized Operation 53
After
{
  "zip": "96817",
  "city": "Honolulu",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey L. Berenberg, MD",
      "role": "CONTACT",
      "phone": "808-433-4089"
    }
  ],
  "facility": "OnCare Hawaii, Incorporated - Kuakini",
  "geoPoint": {
    "lat": 21.30694,
    "lon": -157.85833
  }
}
add /protocolSection/contactsLocationsModule/locations/30
Triage: Uncategorized
Uncategorized Operation 54
After
{
  "zip": "96817",
  "city": "Honolulu",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey Berenberg, M.D.",
      "role": "CONTACT",
      "phone": "808-524-6115"
    }
  ],
  "facility": "OnCare Hawaii-Liliha",
  "geoPoint": {
    "lat": 21.30694,
    "lon": -157.85833
  }
}
add /protocolSection/contactsLocationsModule/locations/31
Triage: Uncategorized
Uncategorized Operation 55
After
{
  "zip": "96826",
  "city": "Honolulu",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey L. Berenberg, MD",
      "role": "CONTACT",
      "phone": "808-433-4089"
    }
  ],
  "facility": "Kapiolani Medical Center for Women and Children",
  "geoPoint": {
    "lat": 21.30694,
    "lon": -157.85833
  }
}
add /protocolSection/contactsLocationsModule/locations/32
Triage: Uncategorized
Uncategorized Operation 56
After
{
  "zip": "96734",
  "city": "Kailua",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey L. Berenberg, MD",
      "role": "CONTACT",
      "phone": "808-433-4089"
    }
  ],
  "facility": "Castle Medical Center",
  "geoPoint": {
    "lat": 21.40241,
    "lon": -157.74054
  }
}
add /protocolSection/contactsLocationsModule/locations/33
Triage: Uncategorized
Uncategorized Operation 57
After
{
  "zip": "96766",
  "city": "Lihue",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey Berenberg, M.D.",
      "role": "CONTACT",
      "phone": "808-433-4089"
    }
  ],
  "facility": "Wilcox Memorial Hospital and Kauai Medical Clinic",
  "geoPoint": {
    "lat": 21.98121,
    "lon": -159.3721
  }
}
add /protocolSection/contactsLocationsModule/locations/34
Triage: Uncategorized
Uncategorized Operation 58
After
{
  "zip": "96701",
  "city": "‘Aiea",
  "state": "Hawaii",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Jeffrey L. Berenberg, MD",
      "role": "CONTACT",
      "phone": "808-433-4089"
    }
  ],
  "facility": "Oncare Hawaii, Incorporated - Pali Momi",
  "geoPoint": {
    "lat": 21.38222,
    "lon": -157.93361
  }
}
add /protocolSection/contactsLocationsModule/locations/35
Triage: Uncategorized
Uncategorized Operation 59
After
{
  "zip": "83706",
  "city": "Boise",
  "state": "Idaho",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Saint Alphonsus Regional Medical Center",
  "geoPoint": {
    "lat": 43.6135,
    "lon": -116.20345
  }
}
add /protocolSection/contactsLocationsModule/locations/36
Triage: Uncategorized
Uncategorized Operation 60
After
{
  "zip": "60126",
  "city": "Elmhurst",
  "state": "Illinois",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Lucio Di Nunno, MD",
      "role": "CONTACT",
      "phone": "806-725-8000"
    }
  ],
  "facility": "Elmhurst Memorial Hospital",
  "geoPoint": {
    "lat": 41.89947,
    "lon": -87.94034
  }
}
add /protocolSection/contactsLocationsModule/locations/37
Triage: Uncategorized
Uncategorized Operation 61
After
{
  "zip": "60426",
  "city": "Harvey",
  "state": "Illinois",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Mark F. Kozloff",
      "role": "CONTACT",
      "phone": "708-339-4800"
    }
  ],
  "facility": "Ingalls Memorial Hospital",
  "geoPoint": {
    "lat": 41.61003,
    "lon": -87.64671
  }
}
add /protocolSection/contactsLocationsModule/locations/38
Triage: Uncategorized
Uncategorized Operation 62
After
{
  "zip": "61265",
  "city": "Moline",
  "state": "Illinois",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "David Spector, M.D.",
      "role": "CONTACT",
      "phone": "309-779-4245"
    }
  ],
  "facility": "Medical Arts Associates Ltd.",
  "geoPoint": {
    "lat": 41.5067,
    "lon": -90.51513
  }
}
add /protocolSection/contactsLocationsModule/locations/45
Triage: Uncategorized
Uncategorized Operation 63
After
{
  "zip": "46202",
  "city": "Indianapolis",
  "state": "Indiana",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Linda Han, M.D.",
      "role": "CONTACT",
      "phone": "317-274-2552"
    }
  ],
  "facility": "IU Health Methodist Hospital",
  "geoPoint": {
    "lat": 39.76838,
    "lon": -86.15804
  }
}
add /protocolSection/contactsLocationsModule/locations/47
Triage: Uncategorized
Uncategorized Operation 64
After
{
  "zip": "46904",
  "city": "Kokomo",
  "state": "Indiana",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Robin Zon",
      "role": "CONTACT",
      "phone": "574-647-6343"
    },
    {
      "name": "Robin Zon",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Community Howard Regional Health",
  "geoPoint": {
    "lat": 40.48643,
    "lon": -86.1336
  }
}
add /protocolSection/contactsLocationsModule/locations/55
Triage: Uncategorized
Uncategorized Operation 65
After
{
  "zip": "46601",
  "city": "South Bend",
  "state": "Indiana",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Robin Zon",
      "role": "CONTACT",
      "phone": "574-647-6343"
    }
  ],
  "facility": "Memorial Hospital of South Bend",
  "geoPoint": {
    "lat": 41.68338,
    "lon": -86.25001
  }
}
add /protocolSection/contactsLocationsModule/locations/57
Triage: Uncategorized
Uncategorized Operation 66
After
{
  "zip": "46391",
  "city": "Westville",
  "state": "Indiana",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Robin Zon",
      "role": "CONTACT",
      "phone": "574-647-6343"
    }
  ],
  "facility": "Michiana Hematology Oncology-PC Westville",
  "geoPoint": {
    "lat": 41.54143,
    "lon": -86.90058
  }
}
add /protocolSection/contactsLocationsModule/locations/60
Triage: Uncategorized
Uncategorized Operation 67
After
{
  "zip": "50325",
  "city": "Clive",
  "state": "Iowa",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Robert J. Behrens",
      "role": "CONTACT",
      "phone": "515-643-8206"
    }
  ],
  "facility": "Mercy Cancer Center - West Lakes",
  "geoPoint": {
    "lat": 41.60304,
    "lon": -93.72411
  }
}
add /protocolSection/contactsLocationsModule/locations/67
Triage: Uncategorized
Uncategorized Operation 68
After
{
  "zip": "50266-7700",
  "city": "West Des Moines",
  "state": "Iowa",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Robert J. Behrens",
      "role": "CONTACT",
      "phone": "515-343-1000"
    }
  ],
  "facility": "Methodist West Hospital",
  "geoPoint": {
    "lat": 41.57721,
    "lon": -93.71133
  }
}
add /protocolSection/contactsLocationsModule/locations/68
Triage: Uncategorized
Uncategorized Operation 69
After
{
  "zip": "50266",
  "city": "West Des Moines",
  "state": "Iowa",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Robert Behrens, M.D.",
      "role": "CONTACT",
      "phone": "515-244-7586"
    }
  ],
  "facility": "Mercy Medical Center-West Lakes",
  "geoPoint": {
    "lat": 41.57721,
    "lon": -93.71133
  }
}
add /protocolSection/contactsLocationsModule/locations/73
Triage: Uncategorized
Uncategorized Operation 70
After
{
  "zip": "04401",
  "city": "Bangor",
  "state": "Maine",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Thomas Openshaw, M.D.",
      "role": "CONTACT",
      "phone": "207-973-7474"
    }
  ],
  "facility": "Eastern Maine Medical Center",
  "geoPoint": {
    "lat": 44.79884,
    "lon": -68.77265
  }
}
add /protocolSection/contactsLocationsModule/locations/74
Triage: Uncategorized
Uncategorized Operation 71
After
{
  "zip": "21229",
  "city": "Baltimore",
  "state": "Maryland",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Richard Hudes, M.D.",
      "role": "CONTACT",
      "phone": "410-368-2965"
    }
  ],
  "facility": "Saint Agnes Hospital",
  "geoPoint": {
    "lat": 39.29038,
    "lon": -76.61219
  }
}
add /protocolSection/contactsLocationsModule/locations/76
Triage: Uncategorized
Uncategorized Operation 72
After
{
  "zip": "02115",
  "city": "Boston",
  "state": "Massachusetts",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Katherina Calvillo, M.D.",
      "role": "CONTACT",
      "phone": "781-624-4611"
    }
  ],
  "facility": "Brigham and Women&#x27;s Hospital",
  "geoPoint": {
    "lat": 42.35843,
    "lon": -71.05977
  }
}
add /protocolSection/contactsLocationsModule/locations/77
Triage: Uncategorized
Uncategorized Operation 73
After
{
  "zip": "02115",
  "city": "Boston",
  "state": "Massachusetts",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Katherina Calvillo, M.D.",
      "role": "CONTACT",
      "phone": "781-624-4611"
    }
  ],
  "facility": "Dana-Farber Cancer Institute",
  "geoPoint": {
    "lat": 42.35843,
    "lon": -71.05977
  }
}
add /protocolSection/contactsLocationsModule/locations/78
Triage: Uncategorized
Uncategorized Operation 74
After
{
  "zip": "02190",
  "city": "South Weymouth",
  "state": "Massachusetts",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Katherina Calvillo, M.D.",
      "role": "CONTACT",
      "phone": "781-624-4611"
    }
  ],
  "facility": "Dana-Farber&#x2F;Brigham and Women&#x27;s Cancer Center at South Shore",
  "geoPoint": {
    "lat": 42.1751,
    "lon": -70.94949
  }
}
add /protocolSection/contactsLocationsModule/locations/79
Triage: Uncategorized
Uncategorized Operation 75
After
{
  "zip": "48106",
  "city": "Ann Arbor",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Michigan Cancer Research Consortium Community Clinical Oncology Program",
  "geoPoint": {
    "lat": 42.27756,
    "lon": -83.74088
  }
}
add /protocolSection/contactsLocationsModule/locations/80
Triage: Uncategorized
Uncategorized Operation 76
After
{
  "zip": "48106",
  "city": "Ann Arbor",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Saint Joseph Mercy Hospital",
  "geoPoint": {
    "lat": 42.27756,
    "lon": -83.74088
  }
}
add /protocolSection/contactsLocationsModule/locations/81
Triage: Uncategorized
Uncategorized Operation 77
After
{
  "zip": "48124",
  "city": "Dearborn",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Oakwood Healthcare Inc",
  "geoPoint": {
    "lat": 42.32226,
    "lon": -83.17631
  }
}
add /protocolSection/contactsLocationsModule/locations/82
Triage: Uncategorized
Uncategorized Operation 78
After
{
  "zip": "48236",
  "city": "Detroit",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Saint John Hospital and Medical Center",
  "geoPoint": {
    "lat": 42.33143,
    "lon": -83.04575
  }
}
add /protocolSection/contactsLocationsModule/locations/83
Triage: Uncategorized
Uncategorized Operation 79
After
{
  "zip": "48503",
  "city": "Flint",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Genesys Hurley Cancer Institute",
  "geoPoint": {
    "lat": 43.01253,
    "lon": -83.68746
  }
}
add /protocolSection/contactsLocationsModule/locations/84
Triage: Uncategorized
Uncategorized Operation 80
After
{
  "zip": "48503",
  "city": "Flint",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Hurley Medical Center",
  "geoPoint": {
    "lat": 43.01253,
    "lon": -83.68746
  }
}
add /protocolSection/contactsLocationsModule/locations/85
Triage: Uncategorized
Uncategorized Operation 81
After
{
  "zip": "49503",
  "city": "Grand Rapids",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Gilbert Padula, M.D.",
      "role": "CONTACT",
      "phone": "616-752-6218"
    }
  ],
  "facility": "Spectrum Health at Butterworth Campus",
  "geoPoint": {
    "lat": 42.96336,
    "lon": -85.66809
  }
}
add /protocolSection/contactsLocationsModule/locations/86
Triage: Uncategorized
Uncategorized Operation 82
After
{
  "zip": "49201",
  "city": "Jackson",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Allegiance Health",
  "geoPoint": {
    "lat": 42.24587,
    "lon": -84.40135
  }
}
add /protocolSection/contactsLocationsModule/locations/87
Triage: Uncategorized
Uncategorized Operation 83
After
{
  "zip": "49001",
  "city": "Kalamazoo",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Raymond S. Lord, MD",
      "role": "CONTACT",
      "phone": "269-373-7458"
    }
  ],
  "facility": "Borgess Medical Center",
  "geoPoint": {
    "lat": 42.29171,
    "lon": -85.58723
  }
}
add /protocolSection/contactsLocationsModule/locations/88
Triage: Uncategorized
Uncategorized Operation 84
After
{
  "zip": "49007",
  "city": "Kalamazoo",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Raymond Lord, M.D.",
      "role": "CONTACT",
      "phone": "269-373-7464"
    }
  ],
  "facility": "Bronson Methodist Hospital",
  "geoPoint": {
    "lat": 42.29171,
    "lon": -85.58723
  }
}
add /protocolSection/contactsLocationsModule/locations/89
Triage: Uncategorized
Uncategorized Operation 85
After
{
  "zip": "49007",
  "city": "Kalamazoo",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Raymond Lord, M.D.",
      "role": "CONTACT",
      "phone": "269-373-7464"
    }
  ],
  "facility": "West Michigan Cancer Center",
  "geoPoint": {
    "lat": 42.29171,
    "lon": -85.58723
  }
}
add /protocolSection/contactsLocationsModule/locations/90
Triage: Uncategorized
Uncategorized Operation 86
After
{
  "zip": "48912",
  "city": "Lansing",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Sparrow Hospital",
  "geoPoint": {
    "lat": 42.73253,
    "lon": -84.55553
  }
}
add /protocolSection/contactsLocationsModule/locations/91
Triage: Uncategorized
Uncategorized Operation 87
After
{
  "zip": "48154",
  "city": "Livonia",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Saint Mary Mercy Hospital",
  "geoPoint": {
    "lat": 42.36837,
    "lon": -83.35271
  }
}
add /protocolSection/contactsLocationsModule/locations/92
Triage: Uncategorized
Uncategorized Operation 88
After
{
  "zip": "48341",
  "city": "Pontiac",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Saint Joseph Mercy Oakland",
  "geoPoint": {
    "lat": 42.63892,
    "lon": -83.29105
  }
}
add /protocolSection/contactsLocationsModule/locations/93
Triage: Uncategorized
Uncategorized Operation 89
After
{
  "zip": "48073",
  "city": "Royal Oak",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Nayana Dekhne",
      "role": "CONTACT",
      "phone": "248-551-3300"
    }
  ],
  "facility": "William Beaumont Hospital-Royal Oak",
  "geoPoint": {
    "lat": 42.48948,
    "lon": -83.14465
  }
}
add /protocolSection/contactsLocationsModule/locations/94
Triage: Uncategorized
Uncategorized Operation 90
After
{
  "zip": "48601",
  "city": "Saginaw",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Saint Mary&#x27;s of Michigan",
  "geoPoint": {
    "lat": 43.41947,
    "lon": -83.95081
  }
}
add /protocolSection/contactsLocationsModule/locations/97
Triage: Uncategorized
Uncategorized Operation 91
After
{
  "zip": "49085",
  "city": "Saint Joseph",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Robin Zon",
      "role": "CONTACT",
      "phone": "574-647-6343"
    }
  ],
  "facility": "Marie Yeager Cancer Center",
  "geoPoint": {
    "lat": 42.10976,
    "lon": -86.48002
  }
}
add /protocolSection/contactsLocationsModule/locations/98
Triage: Uncategorized
Uncategorized Operation 92
After
{
  "zip": "49684",
  "city": "Traverse City",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Gilbert Padula, M.D.",
      "role": "CONTACT",
      "phone": "616-752-6218"
    }
  ],
  "facility": "Munson Medical Center",
  "geoPoint": {
    "lat": 44.76306,
    "lon": -85.62063
  }
}
add /protocolSection/contactsLocationsModule/locations/99
Triage: Uncategorized
Uncategorized Operation 93
After
{
  "zip": "48098",
  "city": "Troy",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Nayana Dekhne, M.D.",
      "role": "CONTACT",
      "phone": "248-551-7695"
    }
  ],
  "facility": "William Beaumont Hospital - Troy",
  "geoPoint": {
    "lat": 42.60559,
    "lon": -83.14993
  }
}
add /protocolSection/contactsLocationsModule/locations/100
Triage: Uncategorized
Uncategorized Operation 94
After
{
  "zip": "48093",
  "city": "Warren",
  "state": "Michigan",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tari Stull, M.D.",
      "role": "CONTACT",
      "phone": "734-712-3456"
    }
  ],
  "facility": "Saint John Macomb-Oakland Hospital",
  "geoPoint": {
    "lat": 42.49044,
    "lon": -83.01304
  }
}
add /protocolSection/contactsLocationsModule/locations/101
Triage: Uncategorized
Uncategorized Operation 95
After
{
  "zip": "56601",
  "city": "Bemidji",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Preston Steen, M.D.",
      "role": "CONTACT",
      "phone": "701-234-6161"
    }
  ],
  "facility": "Sanford Clinic North-Bemidji",
  "geoPoint": {
    "lat": 47.47356,
    "lon": -94.88028
  }
}
add /protocolSection/contactsLocationsModule/locations/102
Triage: Uncategorized
Uncategorized Operation 96
After
{
  "zip": "55337",
  "city": "Burnsville",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel M. Anderson",
      "role": "CONTACT",
      "phone": "952-892-2000"
    }
  ],
  "facility": "Fairview Ridges Hospital",
  "geoPoint": {
    "lat": 44.76774,
    "lon": -93.27772
  }
}
add /protocolSection/contactsLocationsModule/locations/103
Triage: Uncategorized
Uncategorized Operation 97
After
{
  "zip": "55433",
  "city": "Coon Rapids",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Mercy Hospital",
  "geoPoint": {
    "lat": 45.11997,
    "lon": -93.28773
  }
}
add /protocolSection/contactsLocationsModule/locations/104
Triage: Uncategorized
Uncategorized Operation 98
After
{
  "zip": "55805",
  "city": "Duluth",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel A. Nikcevich",
      "role": "CONTACT",
      "phone": "610-402-2273"
    },
    {
      "name": "Daniel A. Nikcevich",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Essentia Health Duluth Clinic CCOP",
  "geoPoint": {
    "lat": 46.78327,
    "lon": -92.10658
  }
}
add /protocolSection/contactsLocationsModule/locations/105
Triage: Uncategorized
Uncategorized Operation 99
After
{
  "zip": "55805",
  "city": "Duluth",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel A. Nikcevich",
      "role": "CONTACT",
      "phone": "610-402-2273"
    },
    {
      "name": "Daniel A. Nikcevich",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Essentia Health Saint Mary&#x27;s Medical Center",
  "geoPoint": {
    "lat": 46.78327,
    "lon": -92.10658
  }
}
add /protocolSection/contactsLocationsModule/locations/106
Triage: Uncategorized
Uncategorized Operation 100
After
{
  "zip": "55805",
  "city": "Duluth",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Nikcevich, MD, PhD",
      "role": "CONTACT",
      "phone": "218-786-3625"
    }
  ],
  "facility": "Miller - Dwan Medical Center",
  "geoPoint": {
    "lat": 46.78327,
    "lon": -92.10658
  }
}
add /protocolSection/contactsLocationsModule/locations/107
Triage: Uncategorized
Uncategorized Operation 101
After
{
  "zip": "55435",
  "city": "Edina",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Fairview-Southdale Hospital",
  "geoPoint": {
    "lat": 44.88969,
    "lon": -93.34995
  }
}
add /protocolSection/contactsLocationsModule/locations/108
Triage: Uncategorized
Uncategorized Operation 102
After
{
  "zip": "55432",
  "city": "Fridley",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Unity Hospital",
  "geoPoint": {
    "lat": 45.08608,
    "lon": -93.26328
  }
}
add /protocolSection/contactsLocationsModule/locations/109
Triage: Uncategorized
Uncategorized Operation 103
After
{
  "zip": "55109",
  "city": "Maplewood",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Minnesota Oncology Hematology PA-Maplewood",
  "geoPoint": {
    "lat": 44.95302,
    "lon": -92.99522
  }
}
add /protocolSection/contactsLocationsModule/locations/110
Triage: Uncategorized
Uncategorized Operation 104
After
{
  "zip": "55109",
  "city": "Maplewood",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Saint John&#x27;s Hospital - Healtheast",
  "geoPoint": {
    "lat": 44.95302,
    "lon": -92.99522
  }
}
add /protocolSection/contactsLocationsModule/locations/111
Triage: Uncategorized
Uncategorized Operation 105
After
{
  "zip": "55407",
  "city": "Minneapolis",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Abbott-Northwestern Hospital",
  "geoPoint": {
    "lat": 44.97997,
    "lon": -93.26384
  }
}
add /protocolSection/contactsLocationsModule/locations/112
Triage: Uncategorized
Uncategorized Operation 106
After
{
  "zip": "55415",
  "city": "Minneapolis",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Hennepin County Medical Center",
  "geoPoint": {
    "lat": 44.97997,
    "lon": -93.26384
  }
}
add /protocolSection/contactsLocationsModule/locations/113
Triage: Uncategorized
Uncategorized Operation 107
After
{
  "zip": "55422",
  "city": "Robbinsdale",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "North Memorial Medical Health Center",
  "geoPoint": {
    "lat": 45.03219,
    "lon": -93.33856
  }
}
add /protocolSection/contactsLocationsModule/locations/115
Triage: Uncategorized
Uncategorized Operation 108
After
{
  "zip": "56303",
  "city": "Saint Cloud",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Donald J. Jurgens",
      "role": "CONTACT",
      "phone": "320-229-4907"
    }
  ],
  "facility": "Coborn Cancer Center",
  "geoPoint": {
    "lat": 45.5608,
    "lon": -94.16249
  }
}
add /protocolSection/contactsLocationsModule/locations/116
Triage: Uncategorized
Uncategorized Operation 109
After
{
  "zip": "56303",
  "city": "Saint Cloud",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Donald Jurgens, M.D.",
      "role": "CONTACT",
      "phone": "320-229-4907"
    }
  ],
  "facility": "Saint Cloud Hospital",
  "geoPoint": {
    "lat": 45.5608,
    "lon": -94.16249
  }
}
add /protocolSection/contactsLocationsModule/locations/117
Triage: Uncategorized
Uncategorized Operation 110
After
{
  "zip": "55416",
  "city": "Saint Louis Park",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Metro-Minnesota CCOP",
  "geoPoint": {
    "lat": 44.9483,
    "lon": -93.34801
  }
}
add /protocolSection/contactsLocationsModule/locations/118
Triage: Uncategorized
Uncategorized Operation 111
After
{
  "zip": "55416",
  "city": "Saint Louis Park",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel M. Anderson",
      "role": "CONTACT",
      "phone": "952-993-3248"
    }
  ],
  "facility": "Park Nicollet Cancer Center",
  "geoPoint": {
    "lat": 44.9483,
    "lon": -93.34801
  }
}
add /protocolSection/contactsLocationsModule/locations/119
Triage: Uncategorized
Uncategorized Operation 112
After
{
  "zip": "55101",
  "city": "Saint Paul",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Regions Hospital",
  "geoPoint": {
    "lat": 44.94441,
    "lon": -93.09327
  }
}
add /protocolSection/contactsLocationsModule/locations/120
Triage: Uncategorized
Uncategorized Operation 113
After
{
  "zip": "55102",
  "city": "Saint Paul",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel M. Anderson",
      "role": "CONTACT",
      "phone": "651-241-8000"
    }
  ],
  "facility": "United Hospital",
  "geoPoint": {
    "lat": 44.94441,
    "lon": -93.09327
  }
}
add /protocolSection/contactsLocationsModule/locations/121
Triage: Uncategorized
Uncategorized Operation 114
After
{
  "zip": "55379",
  "city": "Shakopee",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Saint Francis Regional Medical Center",
  "geoPoint": {
    "lat": 44.79802,
    "lon": -93.5269
  }
}
add /protocolSection/contactsLocationsModule/locations/122
Triage: Uncategorized
Uncategorized Operation 115
After
{
  "zip": "55387",
  "city": "Waconia",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel M. Anderson",
      "role": "CONTACT",
      "phone": "952-442-2191"
    }
  ],
  "facility": "Ridgeview Medical Center",
  "geoPoint": {
    "lat": 44.8508,
    "lon": -93.78691
  }
}
add /protocolSection/contactsLocationsModule/locations/123
Triage: Uncategorized
Uncategorized Operation 116
After
{
  "zip": "56201",
  "city": "Willmar",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Rice Memorial Hospital",
  "geoPoint": {
    "lat": 45.12191,
    "lon": -95.04334
  }
}
add /protocolSection/contactsLocationsModule/locations/124
Triage: Uncategorized
Uncategorized Operation 117
After
{
  "zip": "55125",
  "city": "Woodbury",
  "state": "Minnesota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daniel Anderson, M.D.",
      "role": "CONTACT",
      "phone": "952-993-1517"
    }
  ],
  "facility": "Minnesota Oncology and Hematology PA-Woodbury",
  "geoPoint": {
    "lat": 44.92386,
    "lon": -92.95938
  }
}
add /protocolSection/contactsLocationsModule/locations/125
Triage: Uncategorized
Uncategorized Operation 118
After
{
  "zip": "63703",
  "city": "Cape Girardeau",
  "state": "Missouri",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Alan P. Lyss, MD",
      "role": "CONTACT",
      "phone": "314-996-5514"
    }
  ],
  "facility": "Southeast Cancer Center",
  "geoPoint": {
    "lat": 37.30588,
    "lon": -89.51815
  }
}
add /protocolSection/contactsLocationsModule/locations/126
Triage: Uncategorized
Uncategorized Operation 119
After
{
  "zip": "65109",
  "city": "Jefferson City",
  "state": "Missouri",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Alan Lyss, M.D.",
      "role": "CONTACT",
      "phone": "800-392-0936"
    }
  ],
  "facility": "Capital Region Medical Center-Goldschmidt Cancer Center",
  "geoPoint": {
    "lat": 38.5767,
    "lon": -92.17352
  }
}
add /protocolSection/contactsLocationsModule/locations/134
Triage: Uncategorized
Uncategorized Operation 120
After
{
  "zip": "63131",
  "city": "St Louis",
  "state": "Missouri",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Alan Philip Lyss, MD",
      "role": "CONTACT",
      "email": "alyss@bjc.org",
      "phone": "314-996-5514"
    }
  ],
  "facility": "Missouri Baptist Cancer Center",
  "geoPoint": {
    "lat": 38.62727,
    "lon": -90.19789
  }
}
add /protocolSection/contactsLocationsModule/locations/138
Triage: Uncategorized
Uncategorized Operation 121
After
{
  "zip": "89106",
  "city": "Las Vegas",
  "state": "Nevada",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Ellerton, M.D.",
      "role": "CONTACT",
      "phone": "702-384-0808"
    }
  ],
  "facility": "Nevada Cancer Research Foundation CCOP",
  "geoPoint": {
    "lat": 36.17497,
    "lon": -115.13722
  }
}
add /protocolSection/contactsLocationsModule/locations/139
Triage: Uncategorized
Uncategorized Operation 122
After
{
  "zip": "03756",
  "city": "Lebanon",
  "state": "New Hampshire",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Kari Rosenkranz, M.D.",
      "role": "CONTACT",
      "phone": "800-639-6918"
    }
  ],
  "facility": "Dartmouth Hitchcock Medical Center",
  "geoPoint": {
    "lat": 43.64229,
    "lon": -72.25176
  }
}
add /protocolSection/contactsLocationsModule/locations/140
Triage: Uncategorized
Uncategorized Operation 123
After
{
  "zip": "08103",
  "city": "Camden",
  "state": "New Jersey",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Diana Dickson-Witmer, M.D.",
      "role": "CONTACT",
      "phone": "302-733-6227"
    }
  ],
  "facility": "Cooper Hospital University Medical Center",
  "geoPoint": {
    "lat": 39.92595,
    "lon": -75.11962
  }
}
add /protocolSection/contactsLocationsModule/locations/141
Triage: Uncategorized
Uncategorized Operation 124
After
{
  "zip": "08901",
  "city": "New Brunswick",
  "state": "New Jersey",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Susan McManus, M.D.",
      "role": "CONTACT",
      "phone": "732-745-8600",
      "phoneExt": "6163"
    }
  ],
  "facility": "Saint Peter&#x27;s University Hospital",
  "geoPoint": {
    "lat": 40.48622,
    "lon": -74.45182
  }
}
add /protocolSection/contactsLocationsModule/locations/143
Triage: Uncategorized
Uncategorized Operation 125
After
{
  "zip": "87109",
  "city": "Albuquerque",
  "state": "New Mexico",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Calvin Ridgeway, M.D.",
      "role": "CONTACT",
      "phone": "505-559-6100"
    }
  ],
  "facility": "Lovelace Women&#x27;s Hospital",
  "geoPoint": {
    "lat": 35.08449,
    "lon": -106.65114
  }
}
add /protocolSection/contactsLocationsModule/locations/144
Triage: Uncategorized
Uncategorized Operation 126
After
{
  "zip": "10029",
  "city": "New York",
  "state": "New York",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Elisa Port, M.D.",
      "role": "CONTACT",
      "phone": "212-241-3806"
    }
  ],
  "facility": "Mount Sinai Medical Center",
  "geoPoint": {
    "lat": 40.71427,
    "lon": -74.00597
  }
}
add /protocolSection/contactsLocationsModule/locations/145
Triage: Uncategorized
Uncategorized Operation 127
After
{
  "zip": "12601",
  "city": "Poughkeepsie",
  "state": "New York",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Gregory Zanieski, M.D.",
      "role": "CONTACT",
      "phone": "845-483-6483"
    }
  ],
  "facility": "Vassar Brothers Medical Center",
  "geoPoint": {
    "lat": 41.70037,
    "lon": -73.92097
  }
}
add /protocolSection/contactsLocationsModule/locations/146
Triage: Uncategorized
Uncategorized Operation 128
After
{
  "zip": "14642",
  "city": "Rochester",
  "state": "New York",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Kristin Skinner, M.D.",
      "role": "CONTACT",
      "phone": "585-275-5830"
    }
  ],
  "facility": "University of Rochester",
  "geoPoint": {
    "lat": 43.15478,
    "lon": -77.61556
  }
}
add /protocolSection/contactsLocationsModule/locations/147
Triage: Uncategorized
Uncategorized Operation 129
After
{
  "zip": "27599",
  "city": "Chapel Hill",
  "state": "North Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "David Ollila, M.D.",
      "role": "CONTACT",
      "phone": "877-668-0683"
    }
  ],
  "facility": "University of North Carolina at Chapel Hill",
  "geoPoint": {
    "lat": 35.9132,
    "lon": -79.05584
  }
}
add /protocolSection/contactsLocationsModule/locations/148
Triage: Uncategorized
Uncategorized Operation 130
After
{
  "zip": "28204",
  "city": "Charlotte",
  "state": "North Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Justin Favaro, M.D.",
      "role": "CONTACT",
      "phone": "704-342-1900"
    }
  ],
  "facility": "Presbyterian Hospital",
  "geoPoint": {
    "lat": 35.22709,
    "lon": -80.84313
  }
}
add /protocolSection/contactsLocationsModule/locations/149
Triage: Uncategorized
Uncategorized Operation 131
After
{
  "zip": "28232-2861",
  "city": "Charlotte",
  "state": "North Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Richard L. White, MD",
      "role": "CONTACT",
      "phone": "704-355-3809"
    }
  ],
  "facility": "Carolinas Medical Center",
  "geoPoint": {
    "lat": 35.22709,
    "lon": -80.84313
  }
}
add /protocolSection/contactsLocationsModule/locations/150
Triage: Uncategorized
Uncategorized Operation 132
After
{
  "zip": "27157",
  "city": "Winston-Salem",
  "state": "North Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Edward Levine, M.D.",
      "role": "CONTACT",
      "phone": "336-713-6771"
    }
  ],
  "facility": "Wake Forest University Health Sciences",
  "geoPoint": {
    "lat": 36.09986,
    "lon": -80.24422
  }
}
add /protocolSection/contactsLocationsModule/locations/151
Triage: Uncategorized
Uncategorized Operation 133
After
{
  "zip": "58102",
  "city": "Fargo",
  "state": "North Dakota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Preston Steen, M.D.",
      "role": "CONTACT",
      "phone": "701-234-6161"
    }
  ],
  "facility": "Sanford Clinic North-Fargo",
  "geoPoint": {
    "lat": 46.87719,
    "lon": -96.7898
  }
}
add /protocolSection/contactsLocationsModule/locations/152
Triage: Uncategorized
Uncategorized Operation 134
After
{
  "zip": "58122",
  "city": "Fargo",
  "state": "North Dakota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Preston Steen, M.D.",
      "role": "CONTACT",
      "phone": "701-234-6161"
    }
  ],
  "facility": "Sanford Medical Center-Fargo",
  "geoPoint": {
    "lat": 46.87719,
    "lon": -96.7898
  }
}
add /protocolSection/contactsLocationsModule/locations/153
Triage: Uncategorized
Uncategorized Operation 135
After
{
  "zip": "58122",
  "city": "Fargo",
  "state": "North Dakota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Preston Steen",
      "role": "CONTACT",
      "phone": "701-234-6161"
    },
    {
      "name": "Preston Steen",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Sanford Roger Maris Cancer Center",
  "geoPoint": {
    "lat": 46.87719,
    "lon": -96.7898
  }
}
add /protocolSection/contactsLocationsModule/locations/154
Triage: Uncategorized
Uncategorized Operation 136
After
{
  "zip": "54601",
  "city": "Chillicothe",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "J. P. Kuebler, MD, PhD",
      "role": "CONTACT",
      "phone": "614-442-3130"
    }
  ],
  "facility": "Adena Regional Medical Center",
  "geoPoint": {
    "lat": 39.33312,
    "lon": -82.9824
  }
}
add /protocolSection/contactsLocationsModule/locations/155
Triage: Uncategorized
Uncategorized Operation 137
After
{
  "zip": "43214",
  "city": "Columbus",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "J. P. Kuebler, MD, PhD",
      "role": "CONTACT",
      "phone": "614-442-3130"
    }
  ],
  "facility": "Riverside Methodist Hospital Cancer Care",
  "geoPoint": {
    "lat": 39.96118,
    "lon": -82.99879
  }
}
add /protocolSection/contactsLocationsModule/locations/156
Triage: Uncategorized
Uncategorized Operation 138
After
{
  "zip": "43215",
  "city": "Columbus",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Kuebler, M.D.",
      "role": "CONTACT",
      "phone": "614-488-2118"
    }
  ],
  "facility": "Columbus CCOP",
  "geoPoint": {
    "lat": 39.96118,
    "lon": -82.99879
  }
}
add /protocolSection/contactsLocationsModule/locations/157
Triage: Uncategorized
Uncategorized Operation 139
After
{
  "zip": "43215",
  "city": "Columbus",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "J. Philip Kuebler, MD, PhD",
      "role": "CONTACT",
      "phone": "614-488-2118"
    }
  ],
  "facility": "Grant Medical Center Cancer Care",
  "geoPoint": {
    "lat": 39.96118,
    "lon": -82.99879
  }
}
add /protocolSection/contactsLocationsModule/locations/158
Triage: Uncategorized
Uncategorized Operation 140
After
{
  "zip": "43219",
  "city": "Columbus",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Kuebler, M.D.",
      "role": "CONTACT",
      "phone": "614-488-2118"
    }
  ],
  "facility": "The Mark H Zangmeister Center",
  "geoPoint": {
    "lat": 39.96118,
    "lon": -82.99879
  }
}
add /protocolSection/contactsLocationsModule/locations/159
Triage: Uncategorized
Uncategorized Operation 141
After
{
  "zip": "43222",
  "city": "Columbus",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Kuebler, M.D.",
      "role": "CONTACT",
      "phone": "614-488-2118"
    }
  ],
  "facility": "Mount Carmel Health Center West",
  "geoPoint": {
    "lat": 39.96118,
    "lon": -82.99879
  }
}
add /protocolSection/contactsLocationsModule/locations/160
Triage: Uncategorized
Uncategorized Operation 142
After
{
  "zip": "43228",
  "city": "Columbus",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "J. P. Kuebler, MD, PhD",
      "role": "CONTACT",
      "phone": "614-442-3130"
    }
  ],
  "facility": "Doctors Hospital at Ohio Health",
  "geoPoint": {
    "lat": 39.96118,
    "lon": -82.99879
  }
}
add /protocolSection/contactsLocationsModule/locations/161
Triage: Uncategorized
Uncategorized Operation 143
After
{
  "zip": "43015",
  "city": "Delaware",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "J. Philip Kuebler, MD, PhD",
      "role": "CONTACT",
      "phone": "614-488-2118"
    }
  ],
  "facility": "Grady Memorial Hospital",
  "geoPoint": {
    "lat": 40.29867,
    "lon": -83.06797
  }
}
add /protocolSection/contactsLocationsModule/locations/162
Triage: Uncategorized
Uncategorized Operation 144
After
{
  "zip": "45750",
  "city": "Marietta",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Kuebler, M.D.",
      "role": "CONTACT",
      "phone": "614-566-3275"
    }
  ],
  "facility": "Marietta Memorial Hospital",
  "geoPoint": {
    "lat": 39.41535,
    "lon": -81.45484
  }
}
add /protocolSection/contactsLocationsModule/locations/163
Triage: Uncategorized
Uncategorized Operation 145
After
{
  "zip": "43055",
  "city": "Newark",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "J. Philip Kuebler, MD, PhD",
      "role": "CONTACT",
      "phone": "614-488-2118"
    }
  ],
  "facility": "Licking Memorial Cancer Care Program at Licking Memorial Hospital",
  "geoPoint": {
    "lat": 40.05812,
    "lon": -82.40126
  }
}
add /protocolSection/contactsLocationsModule/locations/164
Triage: Uncategorized
Uncategorized Operation 146
After
{
  "zip": "45662",
  "city": "Portsmouth",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "J. Philip Kuebler, MD, PhD",
      "role": "CONTACT",
      "phone": "614-442-3130"
    }
  ],
  "facility": "Southern Ohio Medical Center Cancer Center",
  "geoPoint": {
    "lat": 38.73174,
    "lon": -82.99767
  }
}
add /protocolSection/contactsLocationsModule/locations/165
Triage: Uncategorized
Uncategorized Operation 147
After
{
  "zip": "45505",
  "city": "Springfield",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Kuebler",
      "role": "CONTACT",
      "phone": "614-442-3130"
    },
    {
      "name": "John Kuebler",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Springfield Regional Medical Center",
  "geoPoint": {
    "lat": 39.92423,
    "lon": -83.80882
  }
}
add /protocolSection/contactsLocationsModule/locations/166
Triage: Uncategorized
Uncategorized Operation 148
After
{
  "zip": "43081",
  "city": "Westerville",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Kuebler, M.D.",
      "role": "CONTACT",
      "phone": "614-488-2118"
    }
  ],
  "facility": "Saint Ann&#x27;s Hospital",
  "geoPoint": {
    "lat": 40.12617,
    "lon": -82.92907
  }
}
add /protocolSection/contactsLocationsModule/locations/167
Triage: Uncategorized
Uncategorized Operation 149
After
{
  "zip": "43701",
  "city": "Zanesville",
  "state": "Ohio",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "John Kuebler, M.D.",
      "role": "CONTACT",
      "phone": "614-566-3275"
    }
  ],
  "facility": "Genesis HealthCare System-Good Samaritan",
  "geoPoint": {
    "lat": 39.94035,
    "lon": -82.01319
  }
}
add /protocolSection/contactsLocationsModule/locations/168
Triage: Uncategorized
Uncategorized Operation 150
After
{
  "zip": "73104",
  "city": "Oklahoma City",
  "state": "Oklahoma",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "William Dooley, M.D.",
      "role": "CONTACT",
      "phone": "405-271-4272"
    }
  ],
  "facility": "University of Oklahoma Health Sciences Center",
  "geoPoint": {
    "lat": 35.46756,
    "lon": -97.51643
  }
}
add /protocolSection/contactsLocationsModule/locations/169
Triage: Uncategorized
Uncategorized Operation 151
After
{
  "zip": "73120",
  "city": "Oklahoma City",
  "state": "Oklahoma",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Alan Hollingsworth, M.D.",
      "role": "CONTACT",
      "phone": "405-752-3388"
    }
  ],
  "facility": "Mercy Health Center",
  "geoPoint": {
    "lat": 35.46756,
    "lon": -97.51643
  }
}
add /protocolSection/contactsLocationsModule/locations/170
Triage: Uncategorized
Uncategorized Operation 152
After
{
  "zip": "97239",
  "city": "Portland",
  "state": "Oregon",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Charlotte Kubicky, M.D.",
      "role": "CONTACT",
      "phone": "503-494-1080"
    }
  ],
  "facility": "Oregon Health and Science University",
  "geoPoint": {
    "lat": 45.52345,
    "lon": -122.67621
  }
}
add /protocolSection/contactsLocationsModule/locations/171
Triage: Uncategorized
Uncategorized Operation 153
After
{
  "zip": "18105",
  "city": "Allentown",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Lori Alfonse, M.D.",
      "role": "CONTACT",
      "phone": "610-402-2273"
    }
  ],
  "facility": "Lehigh Valley Hospital",
  "geoPoint": {
    "lat": 40.60843,
    "lon": -75.49018
  }
}
add /protocolSection/contactsLocationsModule/locations/172
Triage: Uncategorized
Uncategorized Operation 154
After
{
  "zip": "18017",
  "city": "Bethlehem",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Lori Alfonse, M.D.",
      "role": "CONTACT",
      "phone": "610-402-2273"
    }
  ],
  "facility": "Lehigh Valley Hospital - Muhlenberg",
  "geoPoint": {
    "lat": 40.62593,
    "lon": -75.37046
  }
}
add /protocolSection/contactsLocationsModule/locations/173
Triage: Uncategorized
Uncategorized Operation 155
After
{
  "zip": "19010",
  "city": "Bryn Mawr",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Albert DeNittis, M.D.",
      "role": "CONTACT",
      "phone": "484-476-2433"
    }
  ],
  "facility": "Bryn Mawr Hospital",
  "geoPoint": {
    "lat": 40.30396,
    "lon": -80.08672
  }
}
add /protocolSection/contactsLocationsModule/locations/174
Triage: Uncategorized
Uncategorized Operation 156
After
{
  "zip": "17325",
  "city": "Gettysburg",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Thomas Bauer, M.D.",
      "role": "CONTACT",
      "phone": "877-441-7957"
    }
  ],
  "facility": "Adams Cancer Center",
  "geoPoint": {
    "lat": 39.83093,
    "lon": -77.2311
  }
}
add /protocolSection/contactsLocationsModule/locations/175
Triage: Uncategorized
Uncategorized Operation 157
After
{
  "zip": "17331",
  "city": "Hanover",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Thomas Bauer, M.D.",
      "role": "CONTACT",
      "phone": "877-441-7957"
    }
  ],
  "facility": "Cherry Tree Cancer Center",
  "geoPoint": {
    "lat": 39.80066,
    "lon": -76.98304
  }
}
add /protocolSection/contactsLocationsModule/locations/176
Triage: Uncategorized
Uncategorized Operation 158
After
{
  "zip": "17604",
  "city": "Lancaster",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Daleela G. Dodge",
      "role": "CONTACT",
      "phone": "717-544-5511"
    }
  ],
  "facility": "Lancaster General Hospital",
  "geoPoint": {
    "lat": 40.03788,
    "lon": -76.30551
  }
}
add /protocolSection/contactsLocationsModule/locations/177
Triage: Uncategorized
Uncategorized Operation 159
After
{
  "zip": "15232",
  "city": "Pittsburgh",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Gretchen Ahrendt, M.D.",
      "role": "CONTACT",
      "phone": "412-647-2811"
    }
  ],
  "facility": "University of Pittsburgh",
  "geoPoint": {
    "lat": 40.44062,
    "lon": -79.99589
  }
}
add /protocolSection/contactsLocationsModule/locations/178
Triage: Uncategorized
Uncategorized Operation 160
After
{
  "zip": "19096",
  "city": "Wynnewood",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Albert DeNittis, M.D.",
      "role": "CONTACT",
      "phone": "484-476-2433"
    }
  ],
  "facility": "Lankenau Hospital",
  "geoPoint": {
    "lat": 40.00289,
    "lon": -75.27074
  }
}
add /protocolSection/contactsLocationsModule/locations/179
Triage: Uncategorized
Uncategorized Operation 161
After
{
  "zip": "17405",
  "city": "York",
  "state": "Pennsylvania",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Thomas Bauer, M.D.",
      "role": "CONTACT",
      "phone": "717-741-8170"
    }
  ],
  "facility": "WellSpan Health-York Hospital",
  "geoPoint": {
    "lat": 39.9626,
    "lon": -76.72774
  }
}
add /protocolSection/contactsLocationsModule/locations/181
Triage: Uncategorized
Uncategorized Operation 162
After
{
  "zip": "02908",
  "city": "Providence",
  "state": "Rhode Island",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "James Koness, M.D.",
      "role": "CONTACT",
      "phone": "401-456-2268"
    }
  ],
  "facility": "Roger Williams Medical Center",
  "geoPoint": {
    "lat": 41.82399,
    "lon": -71.41283
  }
}
add /protocolSection/contactsLocationsModule/locations/182
Triage: Uncategorized
Uncategorized Operation 163
After
{
  "zip": "29425",
  "city": "Charleston",
  "state": "South Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Megan Baker Ruppel, M.D.",
      "role": "CONTACT",
      "phone": "843-792-9321"
    }
  ],
  "facility": "Medical University of South Carolina",
  "geoPoint": {
    "lat": 32.77632,
    "lon": -79.93275
  }
}
add /protocolSection/contactsLocationsModule/locations/183
Triage: Uncategorized
Uncategorized Operation 164
After
{
  "zip": "29926",
  "city": "Hilton Head Island",
  "state": "South Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Megan Baker Ruppel, M.D.",
      "role": "CONTACT",
      "phone": "843-792-9321"
    }
  ],
  "facility": "Hilton Head Regional Medical Center",
  "geoPoint": {
    "lat": 32.19382,
    "lon": -80.73816
  }
}
add /protocolSection/contactsLocationsModule/locations/184
Triage: Uncategorized
Uncategorized Operation 165
After
{
  "zip": "29169",
  "city": "West Columbia",
  "state": "South Carolina",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Lynn M. Tucker",
      "role": "CONTACT",
      "phone": "803-791-2000"
    }
  ],
  "facility": "Lexington Medical Center",
  "geoPoint": {
    "lat": 33.99349,
    "lon": -81.07398
  }
}
add /protocolSection/contactsLocationsModule/locations/185
Triage: Uncategorized
Uncategorized Operation 166
After
{
  "zip": "57104",
  "city": "Sioux Falls",
  "state": "South Dakota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Miroslaw Mazurczak",
      "role": "CONTACT",
      "phone": "605-328-8000"
    }
  ],
  "facility": "Sanford Cancer Center Oncology Clinic",
  "geoPoint": {
    "lat": 43.54369,
    "lon": -96.72796
  }
}
add /protocolSection/contactsLocationsModule/locations/186
Triage: Uncategorized
Uncategorized Operation 167
After
{
  "zip": "57105",
  "city": "Sioux Falls",
  "state": "South Dakota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Wade Dosch, M.D.",
      "role": "CONTACT",
      "phone": "605-328-1367"
    }
  ],
  "facility": "Avera Cancer Institute",
  "geoPoint": {
    "lat": 43.54369,
    "lon": -96.72796
  }
}
add /protocolSection/contactsLocationsModule/locations/187
Triage: Uncategorized
Uncategorized Operation 168
After
{
  "zip": "57117",
  "city": "Sioux Falls",
  "state": "South Dakota",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Miroslaw Mazurczak, M.D.",
      "role": "CONTACT",
      "phone": "605-328-8000"
    }
  ],
  "facility": "Sanford USD Medical Center - Sioux Falls",
  "geoPoint": {
    "lat": 43.54369,
    "lon": -96.72796
  }
}
add /protocolSection/contactsLocationsModule/locations/191
Triage: Uncategorized
Uncategorized Operation 169
After
{
  "zip": "77030",
  "city": "Houston",
  "state": "Texas",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Barbara Bass, M.D.",
      "role": "CONTACT",
      "phone": "713-441-5132"
    }
  ],
  "facility": "The Methodist Hospital System",
  "geoPoint": {
    "lat": 29.76328,
    "lon": -95.36327
  }
}
add /protocolSection/contactsLocationsModule/locations/193
Triage: Uncategorized
Uncategorized Operation 170
After
{
  "zip": "05602",
  "city": "Berlin Corners",
  "state": "Vermont",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Michelle Sowden, M.D.",
      "role": "CONTACT",
      "email": "michelle.sowden@vtmednet.org"
    }
  ],
  "facility": "Central Vermont Medical Center&#x2F;National Life Cancer Treatment",
  "geoPoint": {
    "lat": 44.21006,
    "lon": -72.57594
  }
}
add /protocolSection/contactsLocationsModule/locations/194
Triage: Uncategorized
Uncategorized Operation 171
After
{
  "zip": "05401",
  "city": "Burlington",
  "state": "Vermont",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Michelle Sowden, M.D.",
      "role": "CONTACT",
      "phone": "802-656-8990"
    }
  ],
  "facility": "University of Vermont",
  "geoPoint": {
    "lat": 44.47588,
    "lon": -73.21207
  }
}
add /protocolSection/contactsLocationsModule/locations/195
Triage: Uncategorized
Uncategorized Operation 172
After
{
  "zip": "23298",
  "city": "Richmond",
  "state": "Virginia",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Laurie Cuttino, M.D.",
      "role": "CONTACT",
      "phone": "804-628-1939"
    }
  ],
  "facility": "Virginia Commonwealth University",
  "geoPoint": {
    "lat": 37.55376,
    "lon": -77.46026
  }
}
add /protocolSection/contactsLocationsModule/locations/196
Triage: Uncategorized
Uncategorized Operation 173
After
{
  "zip": "54301-3526",
  "city": "Green Bay",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Anthony J. Jaslowski",
      "role": "CONTACT",
      "phone": "610-402-2273"
    },
    {
      "name": "Anthony J. Jaslowski",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Green Bay Oncology at Saint Vincent Hospital",
  "geoPoint": {
    "lat": 44.51916,
    "lon": -88.01983
  }
}
add /protocolSection/contactsLocationsModule/locations/201
Triage: Uncategorized
Uncategorized Operation 174
After
{
  "zip": "54311",
  "city": "Green Bay",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "William Owens, M.D.",
      "role": "CONTACT",
      "phone": "800-252-2990"
    }
  ],
  "facility": "Aurora BayCare Medical Center",
  "geoPoint": {
    "lat": 44.51916,
    "lon": -88.01983
  }
}
add /protocolSection/contactsLocationsModule/locations/203
Triage: Uncategorized
Uncategorized Operation 175
After
{
  "zip": "53097",
  "city": "Mequon",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Charles H. I. Tiber, MD",
      "role": "CONTACT",
      "phone": "414-291-1840"
    }
  ],
  "facility": "Columbia Saint Mary&#x27;s Hospital - Ozaukee",
  "geoPoint": {
    "lat": 43.21555,
    "lon": -88.03001
  }
}
add /protocolSection/contactsLocationsModule/locations/204
Triage: Uncategorized
Uncategorized Operation 176
After
{
  "zip": "53211",
  "city": "Milwaukee",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Charles Tiber, M.D.",
      "role": "CONTACT",
      "phone": "414-326-2675"
    }
  ],
  "facility": "Columbia Saint Mary&#x27;s Water Tower Medical Commons",
  "geoPoint": {
    "lat": 43.0389,
    "lon": -87.90647
  }
}
add /protocolSection/contactsLocationsModule/locations/205
Triage: Uncategorized
Uncategorized Operation 177
After
{
  "zip": "53215",
  "city": "Milwaukee",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Judy Tjoe, M.D.",
      "role": "CONTACT",
      "phone": "800-252-2990"
    }
  ],
  "facility": "Aurora Saint Luke&#x27;s Medical Center",
  "geoPoint": {
    "lat": 43.0389,
    "lon": -87.90647
  }
}
add /protocolSection/contactsLocationsModule/locations/206
Triage: Uncategorized
Uncategorized Operation 178
After
{
  "zip": "53226",
  "city": "Milwaukee",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Tina Yen, M.D.",
      "role": "CONTACT",
      "phone": "414-805-4380"
    }
  ],
  "facility": "Froedtert and the Medical College of Wisconsin",
  "geoPoint": {
    "lat": 43.0389,
    "lon": -87.90647
  }
}
add /protocolSection/contactsLocationsModule/locations/207
Triage: Uncategorized
Uncategorized Operation 179
After
{
  "zip": "53233",
  "city": "Milwaukee",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Judy Tjoe, M.D.",
      "role": "CONTACT",
      "phone": "800-252-2990"
    }
  ],
  "facility": "Aurora Sinai Medical Center",
  "geoPoint": {
    "lat": 43.0389,
    "lon": -87.90647
  }
}
add /protocolSection/contactsLocationsModule/locations/208
Triage: Uncategorized
Uncategorized Operation 180
After
{
  "zip": "54904",
  "city": "Oshkosh",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "William Owen, M.D.",
      "role": "CONTACT",
      "phone": "800-252-2990"
    }
  ],
  "facility": "Vince Lombardi Cancer Clinic - Oshkosh",
  "geoPoint": {
    "lat": 44.02471,
    "lon": -88.54261
  }
}
add /protocolSection/contactsLocationsModule/locations/209
Triage: Uncategorized
Uncategorized Operation 181
After
{
  "zip": "53066",
  "city": "Summit",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "William Owens, M.D.",
      "role": "CONTACT",
      "phone": "800-252-2990"
    }
  ],
  "facility": "Aurora Medical Center in Summit"
}
add /protocolSection/contactsLocationsModule/locations/210
Triage: Uncategorized
Uncategorized Operation 182
After
{
  "zip": "53227",
  "city": "West Allis",
  "state": "Wisconsin",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Judy Tjoe, M.D.",
      "role": "CONTACT",
      "phone": "800-252-2990"
    }
  ],
  "facility": "Aurora Women&#x27;s Pavilion of Aurora West Allis Medical Center",
  "geoPoint": {
    "lat": 43.01668,
    "lon": -88.00703
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 4 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2012-10
After
2013-11
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 4
Before
2013-01-30
After
2013-11-20
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 5
Before
2013-01-31
After
2013-11-21
replace /protocolSection/descriptionModule/detailedDescription
Triage: Uncategorized
Uncategorized Operation 10
Before
<p>OBJECTIVES:</p><p>Primary</p><ul><li>To assess the local recurrence (LR) rate with breast-conservation in patients with multiple ipsilateral primary breast cancer (MIBC).</li></ul><p>Secondary</p><ul><li>To examine the conversion rate to mastectomy secondary to persistent positive margins; poor cosmesis within the first year of attempting breast-conservation surgery (BCS) or inability to satisfy the radiation dose constraints on the boost to the lumpectomy bed of each site of disease.</li><li>To assess patient&#x27;s perception of cosmesis and incidence of breast lymphedema.</li><li>To examine the type and severity of adverse effects of BCS and radiation for women with MIBC.</li><li>To examine the radiation-related side effects of whole-breast radiation with a boost to 1 large or &gt; 1 lumpectomy site.</li><li>To evaluate protein and gene expression patterns in tissue taken from each breast lesion and to evaluate the concordance of the findings between these lesions.</li><li>To compare the extent of disease described on imaging (mammography, bilateral breast magnetic resonance imaging [MRI] and other adjunctive imaging modalities) with surgical findings.</li></ul><p>OUTLINE: This is a multicenter study.</p><p>Patients undergo breast-conserving surgery (BCS) with all lesions resected to negative margins using 1 lumpectomy or 2-3 separate lumpectomy incisions at the discretion of the surgeon.
Patients receive adjuvant chemotherapy and&#x2F;or endocrine therapy at the discretion of the treating medical oncologist based on tumor characteristics.</p><p>Within 6-10 weeks after surgery or 8 weeks after completion of cytotoxic chemotherapy, patients undergo adjuvant whole-breast irradiation (WBI) with a boost to the lumpectomy bed of each site of disease 5 days a week for approximately 6 weeks.</p><p>Patients complete the Breast-Conserving Therapy Module (BREAST-Q© subscales) questionnaire 5-30 days after surgery and every 6 months for the first 2 years and the yearly for the next 3 years after WBI.
Patients&#x27; surgeons also complete the questionnaire 5-30 days after performing final surgery to assess cosmetic outcomes.</p><p>Formalin-fixed paraffin-embedded (FFPE) tissue block from each site of disease are collected during BCS for protein and gene expression pattern studies.
Blood samples may be also collected at baseline and during BCS.</p><p>After completion of study treatment, patients are followed up every 6 months for 2 years and then yearly for years 3-5.</p>
After
<p>OBJECTIVES:</p><p>Primary</p><ul><li>To assess the local recurrence (LR) rate with breast-conservation in patients with multiple ipsilateral primary breast cancer (MIBC).</li></ul><p>Secondary</p><ul><li>To examine the conversion rate to mastectomy secondary to persistent positive margins; poor cosmesis within the first year of attempting breast-conservation surgery (BCS) or inability to satisfy the radiation dose constraints on the boost to the lumpectomy bed of each site of disease.</li><li>To assess whether patients who did not undergo re-excision for close margins (&lt; 2 mm) have a higher local recurrence (LR) rate than patients for whom negative margins were achieved.</li><li>To assess patient&#x27;s perception of cosmesis and incidence of breast lymphedema.</li><li>To examine the type and severity of adverse effects of BCS and radiation for women with MIBC.</li><li>To assess incidence of breast lymphedema</li><li>To examine the radiation-related side effects of whole-breast radiation with a boost to 1 large or &gt; 1 lumpectomy site.</li></ul><p>OUTLINE: This is a multicenter study.</p><p>Patients undergo breast-conserving surgery (BCS) with all lesions resected to negative margins using 1 lumpectomy or 2-3 separate lumpectomy incisions at the discretion of the surgeon.
Patients receive adjuvant chemotherapy and&#x2F;or endocrine therapy at the discretion of the treating medical oncologist based on tumor characteristics.</p><p>Within 6-10 weeks after surgery or 8 weeks after completion of cytotoxic chemotherapy, patients undergo adjuvant whole-breast irradiation (WBI) with a boost to the lumpectomy bed of each site of disease 5 days a week for approximately 6 weeks at the discretion of the surgeon.</p><p>Patients complete the Breast-Conserving Therapy Module (BREAST-Q© subscales) questionnaire 5-30 days after surgery and every 6 months for the first 2 years and the yearly for the next 3 years after WBI.
Patients&#x27; surgeons also complete the questionnaire 5-30 days after performing final surgery to assess cosmetic outcomes.</p><p>After completion of study treatment, patients are followed up every 6 months for 2 years and then yearly for years 3-5.</p>
Sponsor and administrative fields Sponsor, collaborator, oversight, or registry maintenance changes. Triage: Uncategorized 7 ops
replace /protocolSection/identificationModule/organization/fullName
Triage: Uncategorized
Uncategorized Operation 1
Before
National Cancer Institute (NCI)
After
Alliance for Clinical Trials in Oncology
replace /protocolSection/identificationModule/organization/class
Triage: Uncategorized
Uncategorized Operation 2
Before
NIH
After
OTHER
remove /protocolSection/sponsorCollaboratorsModule/responsibleParty/oldNameTitle
Triage: Uncategorized
Uncategorized Operation 6
Before
Heidi Nelson
remove /protocolSection/sponsorCollaboratorsModule/responsibleParty/oldOrganization
Triage: Uncategorized
Uncategorized Operation 7
Before
American College of Surgeons Oncology Group
add /protocolSection/sponsorCollaboratorsModule/responsibleParty/type
Triage: Uncategorized
Uncategorized Operation 8
After
SPONSOR
replace /protocolSection/sponsorCollaboratorsModule/leadSponsor/name
Triage: Uncategorized
Uncategorized Operation 9
Before
American College of Surgeons
After
Alliance for Clinical Trials in Oncology
add /protocolSection/oversightModule
Triage: Uncategorized
Uncategorized Operation 183
After
{
  "oversightHasDmc": true
}
Raw JSON Patch
[
  {
    "op": "replace",
    "path": "/protocolSection/identificationModule/organization/fullName",
    "value": "Alliance for Clinical Trials in Oncology"
  },
  {
    "op": "replace",
    "path": "/protocolSection/identificationModule/organization/class",
    "value": "OTHER"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2013-11"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2013-11-20"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2013-11-21"
  },
  {
    "op": "remove",
    "path": "/protocolSection/sponsorCollaboratorsModule/responsibleParty/oldNameTitle"
  },
  {
    "op": "remove",
    "path": "/protocolSection/sponsorCollaboratorsModule/responsibleParty/oldOrganization"
  },
  {
    "op": "add",
    "path": "/protocolSection/sponsorCollaboratorsModule/responsibleParty/type",
    "value": "SPONSOR"
  },
  {
    "op": "replace",
    "path": "/protocolSection/sponsorCollaboratorsModule/leadSponsor/name",
    "value": "Alliance for Clinical Trials in Oncology"
  },
  {
    "op": "replace",
    "path": "/protocolSection/descriptionModule/detailedDescription",
    "value": "<p>OBJECTIVES:</p><p>Primary</p><ul><li>To assess the local recurrence (LR) rate with breast-conservation in patients with multiple ipsilateral primary breast cancer (MIBC).</li></ul><p>Secondary</p><ul><li>To examine the conversion rate to mastectomy secondary to persistent positive margins; poor cosmesis within the first year of attempting breast-conservation surgery (BCS) or inability to satisfy the radiation dose constraints on the boost to the lumpectomy bed of each site of disease.</li><li>To assess whether patients who did not undergo re-excision for close margins (&lt; 2 mm) have a higher local recurrence (LR) rate than patients for whom negative margins were achieved.</li><li>To assess patient&#x27;s perception of cosmesis and incidence of breast lymphedema.</li><li>To examine the type and severity of adverse effects of BCS and radiation for women with MIBC.</li><li>To assess incidence of breast lymphedema</li><li>To examine the radiation-related side effects of whole-breast radiation with a boost to 1 large or &gt; 1 lumpectomy site.</li></ul><p>OUTLINE: This is a multicenter study.</p><p>Patients undergo breast-conserving surgery (BCS) with all lesions resected to negative margins using 1 lumpectomy or 2-3 separate lumpectomy incisions at the discretion of the surgeon.\nPatients receive adjuvant chemotherapy and&#x2F;or endocrine therapy at the discretion of the treating medical oncologist based on tumor characteristics.</p><p>Within 6-10 weeks after surgery or 8 weeks after completion of cytotoxic chemotherapy, patients undergo adjuvant whole-breast irradiation (WBI) with a boost to the lumpectomy bed of each site of disease 5 days a week for approximately 6 weeks at the discretion of the surgeon.</p><p>Patients complete the Breast-Conserving Therapy Module (BREAST-Q© subscales) questionnaire 5-30 days after surgery and every 6 months for the first 2 years and the yearly for the next 3 years after WBI.\nPatients&#x27; surgeons also complete the questionnaire 5-30 days after performing final surgery to assess cosmetic outcomes.</p><p>After completion of study treatment, patients are followed up every 6 months for 2 years and then yearly for years 3-5.</p>"
  },
  {
    "op": "add",
    "path": "/protocolSection/designModule/designInfo/allocation",
    "value": "NA"
  },
  {
    "op": "add",
    "path": "/protocolSection/designModule/designInfo/interventionModel",
    "value": "SINGLE_GROUP"
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/interventions/0/type",
    "value": "PROCEDURE"
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/interventions/0/name",
    "value": "therapeutic conventional surgery"
  },
  {
    "op": "add",
    "path": "/protocolSection/armsInterventionsModule/interventions/0/armGroupLabels",
    "value": [
      "Breast conservation surgery and radiation therapy"
    ]
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/interventions/1/type",
    "value": "RADIATION"
  },
  {
    "op": "replace",
    "path": "/protocolSection/armsInterventionsModule/interventions/1/name",
    "value": "whole breast irradiation"
  },
  {
    "op": "add",
    "path": "/protocolSection/armsInterventionsModule/interventions/1/armGroupLabels",
    "value": [
      "Breast conservation surgery and radiation therapy"
    ]
  },
  {
    "op": "remove",
    "path": "/protocolSection/armsInterventionsModule/interventions/2"
  },
  {
    "op": "remove",
    "path": "/protocolSection/armsInterventionsModule/interventions/2"
  },
  {
    "op": "remove",
    "path": "/protocolSection/armsInterventionsModule/interventions/2"
  },
  {
    "op": "remove",
    "path": "/protocolSection/armsInterventionsModule/interventions/2"
  },
  {
    "op": "remove",
    "path": "/protocolSection/armsInterventionsModule/interventions/2"
  },
  {
    "op": "remove",
    "path": "/protocolSection/armsInterventionsModule/interventions/2"
  },
  {
    "op": "add",
    "path": "/protocolSection/armsInterventionsModule/armGroups",
    "value": [
      {
        "type": "EXPERIMENTAL",
        "label": "Breast conservation surgery and radiation therapy",
        "description": "Patients undergo breast conserving surgery with all lesions resected to negative margins using one lumpectomy or 2-3 separate lumpectomy incisions at the discretion of the surgeon.\nPatients receive adjuvant chemotherapy and&#x2F;or endocrine therapy at the discretion of the treating medical oncologist based on tumor characteristics.\nWithin 6-10 weeks after surgery or 8 weeks after completion of cytotoxic chemotherapy, patients undergo adjuvant whole breast irradiation with a boost to the lumpectomy bed of each site of disease 5 days per week for approximately 6 weeks.",
        "interventionNames": [
          "Procedure: therapeutic conventional surgery",
          "Radiation: whole breast irradiation"
        ]
      }
    ]
  },
  {
    "op": "add",
    "path": "/protocolSection/outcomesModule/primaryOutcomes/0/timeFrame",
    "value": "Up to 5 years post-treatment"
  },
  {
    "op": "replace",
    "path": "/protocolSection/outcomesModule/secondaryOutcomes/0/measure",
    "value": "Conversion rate to mastectomy secondary to persistent positive margins assessed"
  },
  {
    "op": "add",
    "path": "/protocolSection/outcomesModule/secondaryOutcomes/0/timeFrame",
    "value": "Up to 5 years post-treatment"
  },
  {
    "op": "add",
    "path": "/protocolSection/outcomesModule/secondaryOutcomes/1/timeFrame",
    "value": "Up to 30 days post-treatment"
  },
  {
    "op": "add",
    "path": "/protocolSection/outcomesModule/secondaryOutcomes/2/timeFrame",
    "value": "Up to 30 days post-treatment"
  },
  {
    "op": "add",
    "path": "/protocolSection/outcomesModule/secondaryOutcomes/3/timeFrame",
    "value": "Up to 2 years post-treatment"
  },
  {
    "op": "replace",
    "path": "/protocolSection/eligibilityModule/eligibilityCriteria",
    "value": "<p>Registration Inclusion Criteria:</p><ol><li>Age ≥ 40 years per National Comprehensive Cancer Network (NCCN) recommendations for breast conservation.</li><li>Life Expectancy of at least 5 years, excluding diagnosis of breast cancer (Comorbid conditions should be taken into consideration, but breast cancer diagnosis is not a consideration)</li><li><p>Female Gender - Men are excluded from this study.\nMale breast cancer is a rare event.</p><p>Men are rarely candidates for breast conservation surgery due to small breast size.\nMen are less likely to be candidates for breast conservation surgery if found to have MIBC.</p></li><li><p>Foci of Breast Cancer - Upon clinical exam and pre-operative imaging by both MRI and mammogram, two or three foci of biopsy proven breast cancer separated by &gt; 2 cm of normal breast tissue.\nFoci must include at least one focus of invasive breast carcinoma with another focus of either invasive breast carcinoma or ductal carcinoma in situ (DCIS).</p><p>No more than 2 quadrants with biopsy proven breast cancer.</p><p>Note: Patient is eligible for study if lesion is not visualized on both imaging modalities (i.e., any of the lesion(s) is&#x2F;are visualized on MRI but not on mammogram OR visualized on mammogram but not on MRI).\nUltrasound cannot be used to determine patient eligibility; eligibility to be determined by bilateral mammogram and MRI only.\nPatient may remain on study if, upon pathological assessment, two or three lesions identified on pre-operative imaging represent one contiguous lesion.</p></li><li>Mammogram Imaging - Bilateral mammogram ≤ 60 days prior to registration</li><li>MRI Imaging - Bilateral breast MRI ≤ 60 days prior to registration</li><li>Staging of Cancer - cN0 or cN1 disease</li><li><p>ECOG Performance Status (PS) - 0, 1, or 2.</p><p>Note: An ECOG PS scale is available on the Cancer Trial Support Unit (CTSU) website.</p></li><li><p>Hemoglobin and Platelet Count - The following laboratory values obtained ≤ 21 days prior to registration:</p><ul><li>Hemoglobin (Hgb) ≥ 8 g&#x2F;dL</li><li>Peripheral platelet count (PLT) ≥ 50,000&#x2F;mm3</li></ul></li><li>Pregnancy for Women of Childbearing Potential - Negative urine or serum pregnancy test result ≤ 7 days prior to registration for women of childbearing potential only.</li><li>Ability to Complete Questionnaires by themselves or with assistance.</li><li>Ability to Provide Written Informed Consent</li><li>Willing to return to enrolling institution for follow-up during the Active Monitoring Phase (the active treatment and observation portions) of the study.\nPatients are encouraged to return to the enrolling institution; however, patients may receive radiation therapy at a different institution other than the enrolling institution.</li></ol><p>Registration Exclusion Criteria:</p><ol><li><p>Pregnancy, Nursing and Requirement for Contraception Any of the following because this study involves radiation therapy (WBI) that has known genotoxic, mutagenic and teratogenic effects:</p><ul><li>Pregnant women</li><li>Nursing women</li><li>Women of childbearing potential who are unwilling to employ adequate contraception (as determined by the treating physician)</li></ul></li><li>Size of Single Focus of Disease - Largest single focus of disease &gt; 5 centimeters by either mammogram or MRI or both.\nNote: Measurement of the largest single focus should include any satellite lesions within 1centimeter of the index lesion.</li><li><p>Prior Staging Procedure - Surgical axillary staging procedure prior to study entry.</p><p>Note: FNA or core needle biopsy of axillary node is permitted.</p></li><li>Evidence of Metastatic Disease - Clinical or radiographic evidence of metastatic disease</li><li>Prior history of ipsilateral breast cancer [DCIS, LCIS (lobular cancer in situ) or invasive]</li><li>Staging of Cancer - cNX, cN2, or cN3 disease</li><li><p>Breast Implants at time of diagnosis.</p><p>Note: Patients who have had implants previously removed prior to diagnosis are eligible.</p></li><li>Systemic Illnesses or Concurrent Disease - Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would interfere significantly with whole breast irradiation (such as connective tissue disorders, lupus, scleroderma).</li><li>Uncontrolled Intercurrent Illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness&#x2F;social situations that would limit compliance with study requirements.</li><li>Bilateral Breast Cancer Prior or current LCIS, DCIS or invasive breast cancer in the opposite breast (i.e., bilateral disease is not allowed).</li><li>Disallowed Prior Treatments - Treatment including radiation therapy, chemotherapy, biotherapy, hormonal therapy for this cancer prior to registration.</li><li>Chemotherapy or Endocrine Therapy Prior to Surgery - Neoadjuvant chemotherapy or neoadjuvant endocrine therapy (in other words, no chemotherapy or endocrine therapy prior to surgery) for this cancer.</li><li>Partial Breast Radiation - Planned partial breast radiation.</li><li>Investigational Agents - Administration of any investigational agent ≤ 30 days prior to registration.</li><li>Known BRCA Mutations - Patients with known BRCA mutations.</li><li>Other Active Malignancies - Other active malignancy ≤ 5 years prior to registration.</li></ol><p>Exceptions: Non-melanotic skin cancer or carcinoma-in-situ of the cervix.\nNote: If there is a history of prior malignancy, they must not be receiving other specific treatment for their cancer.</p>"
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]