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NCT02297412

Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel

Version 4 to 5 · Academic and Community Cancer Research United

Patch inspector

Version 4 to 5

43 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:44:38+00
Raw hash
ed31c0281dae3fcd9991b4e389ecb337c1530767f5066f85f72c7d1b62c6eb09
Payload
Source URL
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 39 ops
remove /protocolSection/contactsLocationsModule/centralContacts
Triage: Low
Administrative Contact Change Operation 5
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
[
  {
    "name": "Research Coordinating Center",
    "role": "CONTACT",
    "phone": "507-538-7448"
  }
]
remove /protocolSection/contactsLocationsModule/locations/0/status
Triage: Uncategorized
Uncategorized Operation 6
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/0/contacts
Triage: Uncategorized
Uncategorized Operation 7
Before
[
  {
    "name": "Diane DeVos-Schmidt",
    "role": "CONTACT",
    "phone": "805-474-9143"
  },
  {
    "name": "David Palchak, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/1/status
Triage: Uncategorized
Uncategorized Operation 8
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/1/contacts
Triage: Uncategorized
Uncategorized Operation 9
Before
[
  {
    "name": "Nancy J Williams",
    "role": "CONTACT",
    "email": "nwilliams@illinoiscancercare.com",
    "phone": "309-243-3614"
  },
  {
    "name": "Sachdev P Thomas, MD",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/2/status
Triage: Uncategorized
Uncategorized Operation 10
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/2/contacts
Triage: Uncategorized
Uncategorized Operation 11
Before
[
  {
    "name": "Carle Cancer Center Research",
    "role": "CONTACT",
    "email": "Cancer.Resaerch@Carle.com",
    "phone": "217-383-3516"
  },
  {
    "name": "James R. Egner, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/3/status
Triage: Uncategorized
Uncategorized Operation 12
Before
NOT_YET_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/3/contacts
Triage: Uncategorized
Uncategorized Operation 13
Before
[
  {
    "name": "Sherri Rickabaugh",
    "role": "CONTACT",
    "phone": "515-244-7586"
  },
  {
    "name": "Robert Behrens, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/4/status
Triage: Uncategorized
Uncategorized Operation 14
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/4/contacts
Triage: Uncategorized
Uncategorized Operation 15
Before
[
  {
    "name": "Donald B. Wender, M.D.",
    "role": "CONTACT",
    "email": "drednew@msm.com",
    "phone": "712-252-0088"
  },
  {
    "name": "Donald B. Wender, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/5/status
Triage: Uncategorized
Uncategorized Operation 16
Before
NOT_YET_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/5/contacts
Triage: Uncategorized
Uncategorized Operation 17
Before
[
  {
    "name": "Beth LaVasseur",
    "role": "CONTACT",
    "phone": "734-712-5658"
  },
  {
    "name": "Phillip Stella, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/6/status
Triage: Uncategorized
Uncategorized Operation 18
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/6/contacts
Triage: Uncategorized
Uncategorized Operation 19
Before
[
  {
    "name": "Clinical Trials Referrals Office",
    "role": "CONTACT",
    "phone": "855-776-0015"
  },
  {
    "name": "Charles L. Loprinzi",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/7/status
Triage: Uncategorized
Uncategorized Operation 20
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/7/contacts
Triage: Uncategorized
Uncategorized Operation 21
Before
[
  {
    "name": "Stacy St. Onge, RN",
    "role": "CONTACT",
    "phone": "320-229-4907"
  },
  {
    "name": "Donald J Jurgens, MD",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/8/status
Triage: Uncategorized
Uncategorized Operation 22
Before
NOT_YET_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/8/contacts
Triage: Uncategorized
Uncategorized Operation 23
Before
[
  {
    "name": "Daniel Anderson, M.D.",
    "role": "CONTACT",
    "email": "Daniel.m.anderson@healthpartners.com",
    "phone": "952-993-1517"
  },
  {
    "name": "Daniel Anderson, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/9/status
Triage: Uncategorized
Uncategorized Operation 24
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/9/contacts
Triage: Uncategorized
Uncategorized Operation 25
Before
[
  {
    "name": "Mary Beth Wilwerding, RN",
    "role": "CONTACT",
    "email": "mwilwerding@mvcc.cc",
    "phone": "402-991-8070"
  },
  {
    "name": "Gamini Soori, MD",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/10/status
Triage: Uncategorized
Uncategorized Operation 26
Before
NOT_YET_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/10/contacts
Triage: Uncategorized
Uncategorized Operation 27
Before
[
  {
    "name": "Kelly Cohn",
    "role": "CONTACT",
    "phone": "315-472-7504"
  },
  {
    "name": "Jeffrey J. Kirshner, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/11/status
Triage: Uncategorized
Uncategorized Operation 28
Before
NOT_YET_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/11/contacts
Triage: Uncategorized
Uncategorized Operation 29
Before
[
  {
    "name": "Ruth Fielden",
    "role": "CONTACT",
    "phone": "704-384-8920"
  },
  {
    "name": "Justin Favaro, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/12/status
Triage: Uncategorized
Uncategorized Operation 30
Before
NOT_YET_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/12/contacts
Triage: Uncategorized
Uncategorized Operation 31
Before
[
  {
    "name": "Jeffrey Crawford, M.D.",
    "role": "CONTACT",
    "email": "craw006@mc.duke.edu",
    "phone": "919-681-9509"
  },
  {
    "name": "Jeffrey Crawford, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/13/status
Triage: Uncategorized
Uncategorized Operation 32
Before
NOT_YET_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/13/contacts
Triage: Uncategorized
Uncategorized Operation 33
Before
[
  {
    "name": "Karen Morris",
    "role": "CONTACT",
    "phone": "828-696-4716"
  },
  {
    "name": "James Radford, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/14/status
Triage: Uncategorized
Uncategorized Operation 34
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/14/contacts
Triage: Uncategorized
Uncategorized Operation 35
Before
[
  {
    "name": "Elizabeth White",
    "role": "CONTACT",
    "phone": "336-718-8461"
  },
  {
    "name": "Judith Hopkins, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/15/status
Triage: Uncategorized
Uncategorized Operation 36
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/15/contacts
Triage: Uncategorized
Uncategorized Operation 37
Before
[
  {
    "name": "Kay Culver",
    "role": "CONTACT",
    "email": "kculver@altru.org",
    "phone": "701-780-6738"
  },
  {
    "name": "Wanda DeKrey",
    "role": "CONTACT",
    "email": "wdekrey@altru.org",
    "phone": "701-780-6520"
  },
  {
    "name": "Grant Seeger, MD",
    "role": "PRINCIPAL_INVESTIGATOR"
  },
  {
    "name": "Todor Dentchev, MD",
    "role": "SUB_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/16/status
Triage: Uncategorized
Uncategorized Operation 38
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/16/contacts
Triage: Uncategorized
Uncategorized Operation 39
Before
[
  {
    "name": "Emma Locke",
    "role": "CONTACT",
    "phone": "401-274-1122",
    "phoneExt": "48181"
  },
  {
    "name": "Bachir J. Sakr, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/17/status
Triage: Uncategorized
Uncategorized Operation 40
Before
NOT_YET_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/17/contacts
Triage: Uncategorized
Uncategorized Operation 41
Before
[
  {
    "name": "Rhonda Ballew",
    "role": "CONTACT",
    "phone": "864-512-4651"
  },
  {
    "name": "David Griffin, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/18/status
Triage: Uncategorized
Uncategorized Operation 42
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/18/contacts
Triage: Uncategorized
Uncategorized Operation 43
Before
[
  {
    "name": "Lori L. Fellenz, R.N.",
    "role": "CONTACT",
    "email": "fellenz.lori@mcrf.mfldclin.edu",
    "phone": "800-782-8581",
    "phoneExt": "9-4773"
  },
  {
    "name": "Ali W. Bseiso, M.D.",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2015-04
After
2015-07
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2015-04-14
After
2015-07-22
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2015-04-15
After
2015-07-23
Status and stopping reason Recruitment status, termination, suspension, withdrawal, or why-stopped text. Triage: Uncategorized 1 ops
replace /protocolSection/statusModule/overallStatus
Triage: Uncategorized
Uncategorized Operation 2
Before
RECRUITING
After
ACTIVE_NOT_RECRUITING
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2015-07"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/overallStatus",
    "value": "ACTIVE_NOT_RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2015-07-22"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2015-07-23"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/centralContacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/1/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/1/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/2/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/2/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/3/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/3/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/4/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/4/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/5/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/5/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/6/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/6/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/7/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/7/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/8/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/8/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/9/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/9/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/10/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/10/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/11/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/11/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/12/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/12/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/13/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/13/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/14/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/14/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/15/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/15/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/16/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/16/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/17/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/17/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/18/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/18/contacts"
  }
]