Raw JSON Patch
[
{
"op": "replace",
"path": "/protocolSection/identificationModule/briefTitle",
"value": "Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel"
},
{
"op": "add",
"path": "/protocolSection/identificationModule/secondaryIdInfos",
"value": [
{
"id": "NCI-2016-01592",
"type": "REGISTRY",
"domain": "CTRP (Clinical Trial Reporting Program)"
},
{
"id": "RU221408I",
"type": "OTHER",
"domain": "Academic and Community Cancer Research United"
},
{
"id": "P30CA015083",
"link": "https://reporter.nih.gov/quickSearch/P30CA015083",
"type": "NIH"
}
]
},
{
"op": "replace",
"path": "/protocolSection/statusModule/statusVerifiedDate",
"value": "2016-12"
},
{
"op": "replace",
"path": "/protocolSection/statusModule/overallStatus",
"value": "RECRUITING"
},
{
"op": "replace",
"path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
"value": "2016-01"
},
{
"op": "replace",
"path": "/protocolSection/statusModule/primaryCompletionDateStruct/type",
"value": "ACTUAL"
},
{
"op": "replace",
"path": "/protocolSection/statusModule/lastUpdateSubmitDate",
"value": "2016-12-30"
},
{
"op": "replace",
"path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
"value": "2017-01-04"
},
{
"op": "add",
"path": "/protocolSection/sponsorCollaboratorsModule/collaborators",
"value": [
{
"name": "National Cancer Institute (NCI)",
"class": "NIH"
}
]
},
{
"op": "replace",
"path": "/protocolSection/descriptionModule/briefSummary",
"value": "This randomized pilot trial studies how well minocycline hydrochloride works in reducing chemotherapy-induced peripheral neuropathy and acute pain in patients with breast cancer undergoing treatment with paclitaxel.\nDrugs used in chemotherapy, such as paclitaxel, may cause damage to nerves that result in aches, pains, and tingling or numbness of fingers and toes.\nMinocycline hydrochloride may help lessen nerve damage from paclitaxel and improve the quality of life in breast cancer patients."
},
{
"op": "add",
"path": "/protocolSection/descriptionModule/detailedDescription",
"value": "<p>PRIMARY OBJECTIVES:</p><p>I. To estimate whether minocycline hydrochloride (minocycline) can alleviate paclitaxel-induced peripheral neuropathy.</p><p>II.\nTo estimate whether minocycline can alleviate paclitaxel acute pain syndrome (P-APS).</p><p>III.\nTo examine the possible relative toxicities related to minocycline therapy in this study situation.</p><p>OUTLINE: Patients are randomized to 1 of 2 arms.</p><p>ARM I: Patients receive minocycline hydrochloride orally (PO) twice daily (BID) on days 1-7.\nTreatment repeats every 7 days for up to 12 courses in the absence of disease progression or unacceptable toxicity.</p><p>ARM II: Patients receive a placebo PO BID on days 1-7.\nTreatment repeats every 7 days for up to 12 courses in the absence of disease progression or unacceptable toxicity.</p><p>After completion of the study, patients are followed up every month for 6 months.</p>"
},
{
"op": "replace",
"path": "/protocolSection/conditionsModule/conditions/0",
"value": "Acute Pain"
},
{
"op": "add",
"path": "/protocolSection/conditionsModule/conditions/1",
"value": "Breast Carcinoma"
},
{
"op": "add",
"path": "/protocolSection/conditionsModule/conditions/2",
"value": "Peripheral Neuropathy"
},
{
"op": "replace",
"path": "/protocolSection/designModule/phases/0",
"value": "NA"
},
{
"op": "replace",
"path": "/protocolSection/designModule/designInfo/interventionModel",
"value": "PARALLEL"
},
{
"op": "replace",
"path": "/protocolSection/designModule/designInfo/maskingInfo/masking",
"value": "DOUBLE"
},
{
"op": "remove",
"path": "/protocolSection/designModule/designInfo/maskingInfo/whoMasked/1"
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/armGroups/0/label",
"value": "Arm I (minocycline hydrochloride)"
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/armGroups/0/type",
"value": "EXPERIMENTAL"
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/armGroups/0/description",
"value": "Patients receive minocycline hydrochloride PO BID on days 1-7.\nTreatment repeats every 7 days for up to 12 courses in the absence of disease progression or unacceptable toxicity."
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/armGroups/0/interventionNames/0",
"value": "Drug: Minocycline Hydrochloride"
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/armGroups/0/interventionNames/1",
"value": "Other: Quality-of-Life Assessment"
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/armGroups/0/interventionNames/2",
"value": "Other: Questionnaire Administration"
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/armGroups/1/label",
"value": "Arm II (placebo)"
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/armGroups/1/description",
"value": "Patients receive a placebo PO BID on days 1-7.\nTreatment repeats every 7 days for up to 12 courses in the absence of disease progression or unacceptable toxicity."
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/armGroups/1/interventionNames/0",
"value": "Other: Placebo"
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/armGroups/1/interventionNames/1",
"value": "Other: Quality-of-Life Assessment"
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/armGroups/1/interventionNames/2",
"value": "Other: Questionnaire Administration"
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/interventions/0/name",
"value": "Minocycline Hydrochloride"
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/interventions/0/armGroupLabels/0",
"value": "Arm I (minocycline hydrochloride)"
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/interventions/0/description",
"value": "Given PO"
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/interventions/0/otherNames",
"value": [
"Dynacin",
"Minocin",
"Minomax",
"Minomycin",
"Tri-minocycline",
"Vectrin"
]
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/interventions/1/type",
"value": "OTHER"
},
{
"op": "replace",
"path": "/protocolSection/armsInterventionsModule/interventions/1/armGroupLabels/0",
"value": "Arm II (placebo)"
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/interventions/1/description",
"value": "Given PO"
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/interventions/1/otherNames",
"value": [
"placebo therapy",
"PLCB",
"sham therapy"
]
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/interventions/2",
"value": {
"name": "Quality-of-Life Assessment",
"type": "OTHER",
"otherNames": [
"Quality of Life Assessment"
],
"description": "Ancillary studies",
"armGroupLabels": [
"Arm I (minocycline hydrochloride)",
"Arm II (placebo)"
]
}
},
{
"op": "add",
"path": "/protocolSection/armsInterventionsModule/interventions/3",
"value": {
"name": "Questionnaire Administration",
"type": "OTHER",
"description": "Ancillary studies",
"armGroupLabels": [
"Arm I (minocycline hydrochloride)",
"Arm II (placebo)"
]
}
},
{
"op": "replace",
"path": "/protocolSection/outcomesModule/primaryOutcomes/0/measure",
"value": "Paclitaxel-induced acute pain syndrome as assessed by the Acute Pain Syndrome Symptom Summary Questionnaire"
},
{
"op": "replace",
"path": "/protocolSection/outcomesModule/primaryOutcomes/0/description",
"value": "Descriptive statistics and statistical plots will be mainly utilized.\nMeans and 95% CIs will be produced for continuous data for both the minocycline arm and the placebo arm.\nFor categorical/discrete data, frequency counts and percentage will be produced.\nThe mean estimates will be compared and differences in frequency distributions noted."
},
{
"op": "replace",
"path": "/protocolSection/outcomesModule/primaryOutcomes/0/timeFrame",
"value": "Up to course 12"
},
{
"op": "add",
"path": "/protocolSection/outcomesModule/primaryOutcomes/1",
"value": {
"measure": "Paclitaxel-induced peripheral neuropathy as assessed by the European Organization for Research and Treatment of Cancer Chemotherapy-Induced Peripheral Neuropathy 20 questionnaire and follow-up questionnaire",
"timeFrame": "Up to course 12",
"description": "Descriptive statistics and statistical plots will be mainly utilized.\nMeans and 95% confidence intervals (CIs) will be produced for continuous data for both the minocycline arm and the placebo arm.\nFor categorical/discrete data, frequency counts and percentage will be produced.\nThe mean estimates will be compared and differences in frequency distributions noted."
}
},
{
"op": "add",
"path": "/protocolSection/outcomesModule/primaryOutcomes/2",
"value": {
"measure": "Relative toxicities related to minocycline hydrochloride therapy as assessed by the change in the Acute Pain Syndrome Symptom Summary Questionnaire",
"timeFrame": "Baseline to up to course 12",
"description": "Descriptive statistics and statistical plots will be mainly utilized.\nMeans and 95% CIs will be produced for continuous data for both the minocycline arm and the placebo arm.\nFor categorical/discrete data, frequency counts and percentage will be produced.\nThe mean estimates will be compared and differences in frequency distributions noted."
}
},
{
"op": "replace",
"path": "/protocolSection/eligibilityModule/eligibilityCriteria",
"value": "<p>Inclusion Criteria:</p><ul><li>Ability to complete questionnaires by themselves or with assistance</li><li>Planned paclitaxel at a dose of 80 mg/m2 IV given, in the adjuvant breast cancer (postoperative or neo-adjuvant) setting, every week for a planned course of 12 weeks without any other concurrent cytotoxic chemotherapy (trastuzumab and/or other antibody and/or small molecule treatment is allowed, except for PARP inhibitors)</li><li>Life expectancy > 6 months</li><li>Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1</li><li>Negative pregnancy test (serum or urine) done =< 7 days prior to registration, for women of childbearing potential only (determined per clinician discretion)</li></ul><p>Exclusion Criteria:</p><ul><li><p>Any of the following:</p><ul><li>Pregnant women</li><li>Nursing women</li><li>Men or women of childbearing potential who are unwilling to employ adequate contraception</li></ul></li><li>Previous diagnosis of diabetic neuropathy or peripheral neuropathy from any cause</li><li>History of allergic or other adverse reactions to minocycline</li><li>Prior exposure to neurotoxic chemotherapy</li><li>Diagnosis of fibromyalgia</li><li>Current or planned use of methoxyflurane, oral contraceptives, isotretinoin, penicillin, or ergot alkaloids</li><li>History of allergic or other adverse reactions to tetracycline</li></ul>"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/overallOfficials/0/name",
"value": "Charles Loprinzi"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/overallOfficials/0/affiliation",
"value": "Academic and Community Cancer Research United"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/overallOfficials/0/role",
"value": "PRINCIPAL_INVESTIGATOR"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/0/facility",
"value": "PCR Oncology"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/0/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/0/contacts",
"value": [
{
"name": "David L. Palchak",
"role": "CONTACT",
"email": "dpalchak@pcroncology.com",
"phone": "805-474-9143"
},
{
"name": "David L. Palchak",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/1/facility",
"value": "Illinois CancerCare-Community Cancer Center"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/1/city",
"value": "Normal"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/1/zip",
"value": "61761"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/1/geoPoint/lat",
"value": 40.5142
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/1/geoPoint/lon",
"value": -88.99063
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/1/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/1/contacts",
"value": [
{
"name": "Madhuri Bajaj",
"role": "CONTACT",
"email": "mbajaj@illinoiscancecare.com",
"phone": "309-243-3000"
},
{
"name": "Madhuri Bajaj",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/2/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/2/contacts",
"value": [
{
"name": "Vamsi K. Vasireddy",
"role": "CONTACT",
"email": "Vamsi.Vasireddy@Carle.com",
"phone": "800-446-5532"
},
{
"name": "Vamsi K. Vasireddy",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/3/facility",
"value": "Siouxland Regional Cancer Center"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/3/city",
"value": "Sioux City"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/3/zip",
"value": "51101"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/3/geoPoint/lat",
"value": 42.49999
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/3/geoPoint/lon",
"value": -96.40031
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/3/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/3/contacts",
"value": [
{
"name": "Donald B. Wender",
"role": "CONTACT",
"email": "drednew@msn.com",
"phone": "712-252-0088"
},
{
"name": "Donald B. Wender",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/4/facility",
"value": "Michigan Cancer Research Consortium NCORP"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/4/city",
"value": "Ann Arbor"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/4/state",
"value": "Michigan"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/4/zip",
"value": "48106"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/4/geoPoint/lat",
"value": 42.27756
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/4/geoPoint/lon",
"value": -83.74088
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/4/status",
"value": "ACTIVE_NOT_RECRUITING"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/5/facility",
"value": "Mayo Clinic"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/5/city",
"value": "Rochester"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/5/state",
"value": "Minnesota"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/5/zip",
"value": "55905"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/5/geoPoint/lat",
"value": 44.02163
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/5/geoPoint/lon",
"value": -92.4699
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/5/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/5/contacts",
"value": [
{
"name": "Charles L. Loprinzi",
"role": "CONTACT",
"email": "Loprinzi.charles@mayo.edu",
"phone": "507-284-2511"
},
{
"name": "Charles L. Loprinzi",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/6/facility",
"value": "Coborn Cancer Center at Saint Cloud Hospital"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/6/city",
"value": "Saint Cloud"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/6/zip",
"value": "56303"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/6/geoPoint/lat",
"value": 45.5608
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/6/geoPoint/lon",
"value": -94.16249
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/6/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/6/contacts",
"value": [
{
"name": "Donald J. Jurgens",
"role": "CONTACT",
"email": "jurgensd@centracare.com",
"phone": "320-229-4907"
},
{
"name": "Donald J. Jurgens",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/7/facility",
"value": "Missouri Valley Cancer Consortium"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/7/city",
"value": "Omaha"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/7/state",
"value": "Nebraska"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/7/zip",
"value": "68106"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/7/geoPoint/lat",
"value": 41.25626
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/7/geoPoint/lon",
"value": -95.94043
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/7/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/7/contacts",
"value": [
{
"name": "Gamini S. Soori",
"role": "CONTACT",
"email": "gsoori@mvcc.cc",
"phone": "402-991-8070"
},
{
"name": "Gamini S. Soori",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/8/facility",
"value": "Hematology Oncology Associates of Central New York-East Syracuse"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/8/city",
"value": "East Syracuse"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/8/state",
"value": "New York"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/8/zip",
"value": "13057"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/8/geoPoint/lat",
"value": 43.06534
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/8/geoPoint/lon",
"value": -76.07853
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/8/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/8/contacts",
"value": [
{
"name": "Jeffrey J. Kirshner",
"role": "CONTACT",
"email": "jkirshner@hoacny.com",
"phone": "315-472-7504",
"phoneExt": "1350"
},
{
"name": "Jeffrey J. Kirshner",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/9/facility",
"value": "Novant Health Oncology Specialists"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/9/city",
"value": "Winston-Salem"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/9/state",
"value": "North Carolina"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/9/zip",
"value": "27103"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/9/geoPoint/lat",
"value": 36.09986
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/9/geoPoint/lon",
"value": -80.24422
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/9/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/9/contacts",
"value": [
{
"name": "Judith O. Hopkins",
"role": "CONTACT",
"email": "johopkins@novanthealth.org",
"phone": "336-277-8800"
},
{
"name": "Judith O. Hopkins",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/10/facility",
"value": "Women and Infants Hospital"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/10/city",
"value": "Providence"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/10/state",
"value": "Rhode Island"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/10/zip",
"value": "02905"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/10/geoPoint/lat",
"value": 41.82399
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/10/geoPoint/lon",
"value": -71.41283
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/10/status",
"value": "RECRUITING"
},
{
"op": "add",
"path": "/protocolSection/contactsLocationsModule/locations/10/contacts",
"value": [
{
"name": "Bachir J. Sakr",
"role": "CONTACT",
"email": "bsakr@wihri.org",
"phone": "401-453-7520"
},
{
"name": "Bachir J. Sakr",
"role": "PRINCIPAL_INVESTIGATOR"
}
]
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/11/facility",
"value": "Marshfield Clinic"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/11/city",
"value": "Marshfield"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/11/state",
"value": "Wisconsin"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/11/zip",
"value": "54449"
},
{
"op": "replace",
"path": "/protocolSection/contactsLocationsModule/locations/11/geoPoint/lat",
"value": 44.66885
},
{
"op": "replace",
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},
{
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"value": "RECRUITING"
},
{
"op": "add",
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"value": [
{
"name": "Adedayo A. Onitilo",
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"phoneExt": "75416"
},
{
"name": "Adedayo A. Onitilo",
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}
]
},
{
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},
{
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{
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{
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{
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},
{
"op": "remove",
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},
{
"op": "add",
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}
}
]