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NCT02340221

A Study of Taselisib + Fulvestrant Versus Placebo + Fulvestrant in Participants With Advanced or Metastatic Breast Cancer Who Have Disease Recurrence or Progression During or After Aromatase Inhibitor Therapy

Version 55 to 56 · Hoffmann-La Roche

Patch inspector

Version 55 to 56

7 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "signal": "timeline_minor_adjustment",
    "category": "timeline_minor_adjustment",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "low",
    "direction": "earlier",
    "new_value": "2021-06-28",
    "old_value": "2021-07-03",
    "delta_days": 5,
    "date_struct": "completionDateStruct",
    "new_precision": "day",
    "old_precision": "day"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:11:58+00
Raw hash
d0e4ec097fb669484a31f43ca3c7f4cbef60eb0a75581897c3b864c97304dfb4
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 1 ops
replace /protocolSection/statusModule/completionDateStruct/date
Triage: Medium
Timeline Shift Operation 2
Matched rules
  • completion_timeline_change Completion date changes are operational timeline signals.
Before
2021-07-03
After
2021-06-28
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 3 ops
replace /protocolSection/contactsLocationsModule/locations/73/zip
Triage: Uncategorized
Uncategorized Operation 5
Before
546 45
After
546450
remove /protocolSection/contactsLocationsModule/locations/126
Triage: Uncategorized
Uncategorized Operation 6
Before
{
  "zip": "(0)6351",
  "city": "Seoul",
  "country": "South Korea",
  "facility": "Samsung Medical Center",
  "geoPoint": {
    "lat": 37.566,
    "lon": 126.9784
  }
}
add /protocolSection/contactsLocationsModule/locations/130
Triage: Uncategorized
Uncategorized Operation 7
After
{
  "zip": "06531",
  "city": "Seoul",
  "country": "South Korea",
  "facility": "Samsung Medical Center",
  "geoPoint": {
    "lat": 37.566,
    "lon": 126.9784
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2021-03
After
2021-06
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2021-03-12
After
2021-06-15
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2021-03-16
After
2021-06-22
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2021-06"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "value": "2021-06-28"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2021-06-15"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2021-06-22"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/73/zip",
    "value": "546450"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/126"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/130",
    "value": {
      "zip": "06531",
      "city": "Seoul",
      "country": "South Korea",
      "facility": "Samsung Medical Center",
      "geoPoint": {
        "lat": 37.566,
        "lon": 126.9784
      }
    }
  }
]