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NCT02614833

IMP321 (Eftilagimod Alpha) as Adjunctive to a Standard Chemotherapy Paclitaxel Metastatic Breast Carcinoma

Version 31 to 32 · Immutep S.A.S.

Patch inspector

Version 31 to 32

6 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_significant_shift",
    "category": "timeline_significant_shift",
    "new_type": "ACTUAL",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "later",
    "new_value": "2020-03",
    "old_value": "2019-11",
    "delta_days": 121,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "month",
    "old_precision": "month"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:59:26+00
Raw hash
6122102d7b407aa2e47d58e2327f469ea703fa1a1588e3da2f1dbfc4276b1789
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 2 ops
replace /protocolSection/statusModule/primaryCompletionDateStruct/date
Triage: Medium
Timeline Shift Operation 1
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
2019-11
After
2020-03
replace /protocolSection/statusModule/primaryCompletionDateStruct/type
Triage: Medium
Timeline Shift Operation 2
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
ESTIMATED
After
ACTUAL
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 2 ops
remove /protocolSection/contactsLocationsModule/locations/20
Triage: Uncategorized
Uncategorized Operation 5
Before
{
  "zip": "2625",
  "city": "Delft",
  "country": "Netherlands",
  "facility": "Reinier de Graaf Gasthuis",
  "geoPoint": {
    "lat": 52.00667,
    "lon": 4.35556
  }
}
remove /protocolSection/contactsLocationsModule/locations/25
Triage: Uncategorized
Uncategorized Operation 6
Before
{
  "zip": "5022",
  "city": "Tilburg",
  "country": "Netherlands",
  "facility": "ETZ Elisabeth ziekenhuis",
  "geoPoint": {
    "lat": 51.55551,
    "lon": 5.0913
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 2 ops
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2019-07-01
After
2020-06-25
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2019-07-02
After
2020-06-26
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2020-03"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/type",
    "value": "ACTUAL"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2020-06-25"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2020-06-26"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/20"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/25"
  }
]