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NCT03025035

Pembrolizumab in Combination With Olaparib in Advanced BRCA-mutated or HDR-defect Breast Cancer

Version 6 to 7 · Yuan Yuan

Patch inspector

Version 6 to 7

8 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_changeterminal_status_changewhy_stopped_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:58:39+00
Raw hash
353ccbff514c3171d1ac1bd6be45dbdfb88d67aa0e4e00434afada5c583aafca
Payload
Source URL
Status and stopping reason Recruitment status, termination, suspension, withdrawal, or why-stopped text. Triage: High 2 ops
replace /protocolSection/statusModule/overallStatus
Triage: High
Status Termination Operation 2
Matched rules
  • terminal_status_change Status changed to terminated, suspended, or withdrawn; whyStopped content determines whether critical review is warranted.
Before
RECRUITING
After
SUSPENDED
add /protocolSection/statusModule/whyStopped
Triage: High
Status Termination Operation 5
Matched rules
  • why_stopped_change Why-stopped changes explain discontinuation and need review.
After
pending amendment
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 3 ops
remove /protocolSection/contactsLocationsModule/centralContacts
Triage: Low
Administrative Contact Change Operation 6
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
[
  {
    "name": "Emily Riffle",
    "role": "CONTACT",
    "email": "Emily.Riffle@cshs.org",
    "phone": "310-248-6733"
  }
]
remove /protocolSection/contactsLocationsModule/locations/0/status
Triage: Uncategorized
Uncategorized Operation 7
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/0/contacts
Triage: Uncategorized
Uncategorized Operation 8
Before
[
  {
    "name": "Parisa Mirzadehgan, MPH",
    "role": "CONTACT",
    "email": "Parisa.Mirzadehgan@cshs.org",
    "phone": "310-967-4387"
  },
  {
    "name": "Monica Mita, MD",
    "role": "PRINCIPAL_INVESTIGATOR"
  },
  {
    "name": "Philomena McAndrew, MD",
    "role": "SUB_INVESTIGATOR"
  },
  {
    "name": "Heather McArthur, MD",
    "role": "SUB_INVESTIGATOR"
  },
  {
    "name": "Dorothy Park, MD",
    "role": "SUB_INVESTIGATOR"
  },
  {
    "name": "Greg Sarna, MD",
    "role": "SUB_INVESTIGATOR"
  },
  {
    "name": "Alain Mita, MD",
    "role": "SUB_INVESTIGATOR"
  },
  {
    "name": "Reva Basho, MD",
    "role": "SUB_INVESTIGATOR"
  },
  {
    "name": "Bobbie Rimel, MD",
    "role": "SUB_INVESTIGATOR"
  }
]
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2019-03
After
2019-09
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2019-03-07
After
2019-09-04
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2019-03-08
After
2019-09-06
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2019-09"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/overallStatus",
    "value": "SUSPENDED"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2019-09-04"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2019-09-06"
  },
  {
    "op": "add",
    "path": "/protocolSection/statusModule/whyStopped",
    "value": "pending amendment"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/centralContacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/contacts"
  }
]