A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy

[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2020-04"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/overallStatus",
    "value": "ACTIVE_NOT_RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2022-02-02"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "value": "2022-02-02"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2020-04-20"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2020-04-21"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/centralContacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/1/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/2/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/3/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/4/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/5/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/6/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/7/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/8/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/9/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/10/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/11/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/12/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/13/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/14/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/15/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/16/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/17/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/18/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/19/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/20/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/21/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/22/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/23/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/24/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/25/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/26/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/27/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/28/facility",
    "value": "Hämato-Onkologische Schwerpunktpraxis am Klinikum Aschaffenburg"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/28/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/28/city",
    "value": "Aschaffenburg"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/28/zip",
    "value": "63739"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/28/country",
    "value": "Germany"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/28/geoPoint/lat",
    "value": 49.97704
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/28/geoPoint/lon",
    "value": 9.15214
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/29/facility",
    "value": "Universitätsklinikum Erlangen; Frauenklinik"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/29/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/29/city",
    "value": "Erlangen"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/29/zip",
    "value": "91054"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/29/country",
    "value": "Germany"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/29/geoPoint/lat",
    "value": 49.59099
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/29/geoPoint/lon",
    "value": 11.00783
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/30/facility",
    "value": "Klinikum Frankfurt Höchst GmbH"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/30/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/30/city",
    "value": "Frankfurt"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/30/zip",
    "value": "65929"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/30/country",
    "value": "Germany"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/30/geoPoint/lat",
    "value": 49.68333
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/30/geoPoint/lon",
    "value": 10.53333
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/31/facility",
    "value": "Facharztzentrum Eppendorf, Studien GbR"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/31/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/31/city",
    "value": "Hamburg"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/31/zip",
    "value": "20249"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/31/geoPoint/lat",
    "value": 53.55073
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/31/geoPoint/lon",
    "value": 9.99302
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/32/facility",
    "value": "Rotkreuzklinikum München; Frauenklinik"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/32/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/32/city",
    "value": "München"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/32/zip",
    "value": "80637"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/32/geoPoint/lat",
    "value": 51.60698
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/32/geoPoint/lon",
    "value": 13.31243
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/33/facility",
    "value": "Gemeinschaftspraxis für Hämatologie und Onkologie GbR; Dechow & Decker & Nonnenbroich"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/33/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/33/city",
    "value": "Ravensburg"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/33/zip",
    "value": "88212"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/33/geoPoint/lat",
    "value": 47.78198
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/33/geoPoint/lon",
    "value": 9.61062
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/34/facility",
    "value": "Klinikum Südstadt Rostock"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/34/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/34/city",
    "value": "Rostock"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/34/zip",
    "value": "18059"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/34/geoPoint/lat",
    "value": 54.0887
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/34/geoPoint/lon",
    "value": 12.14049
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/35/facility",
    "value": "Royal United Hospital Bath NHS Trust"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/35/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/35/city",
    "value": "Bath"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/35/zip",
    "value": "BA1 3NG"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/35/country",
    "value": "United Kingdom"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/35/geoPoint/lat",
    "value": 51.3751
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/35/geoPoint/lon",
    "value": -2.36172
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/36/facility",
    "value": "Royal Sussex County Hospital"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/36/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/36/city",
    "value": "Brighton"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/36/zip",
    "value": "BN2 5BE"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/36/country",
    "value": "United Kingdom"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/36/geoPoint/lat",
    "value": 50.82838
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/36/geoPoint/lon",
    "value": -0.13947
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/37/facility",
    "value": "Barts Health NHS Trust - St Bartholomew's Hospital"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/37/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/37/city",
    "value": "London"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/37/zip",
    "value": "EC1A 7BE"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/37/country",
    "value": "United Kingdom"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/37/geoPoint/lat",
    "value": 51.50853
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/37/geoPoint/lon",
    "value": -0.12574
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/38/facility",
    "value": "The Christie NHS Foundation Trust"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/38/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/38/city",
    "value": "Manchester"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/38/zip",
    "value": "M20 4BX"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/38/geoPoint/lat",
    "value": 53.48095
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/38/geoPoint/lon",
    "value": -2.23743
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/39/facility",
    "value": "Nottingham University Hospitals NHS Trust - City Hospital"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/39/status"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/39/city",
    "value": "Nottingham"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/39/zip",
    "value": "NG5 1PB"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/39/geoPoint/lat",
    "value": 52.9536
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/39/geoPoint/lon",
    "value": -1.15047
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/40"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/40"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/40"
  }
]