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NCT03735680

A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer

Version 0 to 1 · OncoNano Medicine, Inc.

Patch inspector

Version 0 to 1

9 operations 4 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/startDateStruct/date",
    "signal": "timeline_significant_shift",
    "category": "timeline_significant_shift",
    "new_type": "ACTUAL",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "later",
    "new_value": "2019-08-09",
    "old_value": "2019-02-28",
    "delta_days": 162,
    "date_struct": "startDateStruct",
    "new_precision": "day",
    "old_precision": "day"
  },
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_significant_shift",
    "category": "timeline_significant_shift",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "later",
    "new_value": "2019-12-31",
    "old_value": "2019-09-30",
    "delta_days": 92,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "day",
    "old_precision": "day"
  },
  {
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "signal": "timeline_significant_shift",
    "category": "timeline_significant_shift",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "later",
    "new_value": "2020-01-31",
    "old_value": "2019-10-31",
    "delta_days": 92,
    "date_struct": "completionDateStruct",
    "new_precision": "day",
    "old_precision": "day"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:57:36+00
Raw hash
37e9ae533661d7d613a3515abf79cd3790364de8cd838f1de8b3147af45880e2
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 4 ops
replace /protocolSection/statusModule/startDateStruct/date
Triage: Medium
Timeline Shift Operation 3
Matched rules
  • start_timeline_change Start date changes are operational timeline signals.
Before
2019-02-28
After
2019-08-09
replace /protocolSection/statusModule/startDateStruct/type
Triage: Medium
Timeline Shift Operation 4
Matched rules
  • start_timeline_change Start date changes are operational timeline signals.
Before
ESTIMATED
After
ACTUAL
replace /protocolSection/statusModule/primaryCompletionDateStruct/date
Triage: Medium
Timeline Shift Operation 5
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
2019-09-30
After
2019-12-31
replace /protocolSection/statusModule/completionDateStruct/date
Triage: Medium
Timeline Shift Operation 6
Matched rules
  • completion_timeline_change Completion date changes are operational timeline signals.
Before
2019-10-31
After
2020-01-31
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 1 ops
add /protocolSection/contactsLocationsModule/locations
Triage: Uncategorized
Uncategorized Operation 9
After
[
  {
    "zip": "75390",
    "city": "Dallas",
    "state": "Texas",
    "status": "RECRUITING",
    "country": "United States",
    "contacts": [
      {
        "name": "Herbert Zeh, MD",
        "role": "CONTACT"
      }
    ],
    "facility": "The University of Texas Southwestern Medical Center",
    "geoPoint": {
      "lat": 32.78306,
      "lon": -96.80667
    }
  }
]
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2018-11
After
2019-08
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 7
Before
2018-11-07
After
2019-08-27
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 8
Before
2018-11-08
After
2019-08-29
Status and stopping reason Recruitment status, termination, suspension, withdrawal, or why-stopped text. Triage: Uncategorized 1 ops
replace /protocolSection/statusModule/overallStatus
Triage: Uncategorized
Uncategorized Operation 2
Before
NOT_YET_RECRUITING
After
RECRUITING
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2019-08"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/overallStatus",
    "value": "RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/startDateStruct/date",
    "value": "2019-08-09"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/startDateStruct/type",
    "value": "ACTUAL"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2019-12-31"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "value": "2020-01-31"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2019-08-27"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2019-08-29"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations",
    "value": [
      {
        "zip": "75390",
        "city": "Dallas",
        "state": "Texas",
        "status": "RECRUITING",
        "country": "United States",
        "contacts": [
          {
            "name": "Herbert Zeh, MD",
            "role": "CONTACT"
          }
        ],
        "facility": "The University of Texas Southwestern Medical Center",
        "geoPoint": {
          "lat": 32.78306,
          "lon": -96.80667
        }
      }
    ]
  }
]