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NCT04478279

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

Version 7 to 8 · Sapience Therapeutics

Patch inspector

Version 7 to 8

5 operations 3 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "signal": "timeline_significant_shift",
    "category": "timeline_significant_shift",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "later",
    "new_value": "2024-01",
    "old_value": "2023-01",
    "delta_days": 365,
    "date_struct": "completionDateStruct",
    "new_precision": "month",
    "old_precision": "month"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:57:41+00
Raw hash
2c04686a8c874753d8343457621d19bfc72407cd3bedba0ea3f7b3fc04d07dfe
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 1 ops
replace /protocolSection/statusModule/completionDateStruct/date
Triage: Medium
Timeline Shift Operation 2
Matched rules
  • completion_timeline_change Completion date changes are operational timeline signals.
Before
2023-01
After
2024-01
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Uncategorized 1 ops
add /protocolSection/contactsLocationsModule/locations/1
Triage: Uncategorized
Uncategorized Operation 5
After
{
  "zip": "60555",
  "city": "Warrenville",
  "state": "Illinois",
  "status": "RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Neuro Oncology Research Coordinator",
      "role": "CONTACT",
      "phone": "630-938-2085"
    },
    {
      "name": "Vinai Gondi, MD",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Northwestern Medicine Cancer Centers",
  "geoPoint": {
    "lat": 41.81781,
    "lon": -88.1734
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2021-09
After
2021-11
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2021-09-22
After
2021-11-09
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2021-09-24
After
2021-11-10
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2021-11"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "value": "2024-01"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2021-11-09"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2021-11-10"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/1",
    "value": {
      "zip": "60555",
      "city": "Warrenville",
      "state": "Illinois",
      "status": "RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Neuro Oncology Research Coordinator",
          "role": "CONTACT",
          "phone": "630-938-2085"
        },
        {
          "name": "Vinai Gondi, MD",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "Northwestern Medicine Cancer Centers",
      "geoPoint": {
        "lat": 41.81781,
        "lon": -88.1734
      }
    }
  }
]