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NCT04584853

PreOperative Endocrine Therapy for Individualised Care With Abemaciclib

Version 10 to 11 · Institute of Cancer Research, United Kingdom

Patch inspector

Version 10 to 11

132 operations 5 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_changeenrollment_count_changeenrollment_type_change
Value signals
[
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_minor_adjustment",
    "category": "timeline_minor_adjustment",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "low",
    "direction": "later",
    "new_value": "2030-10",
    "old_value": "2030-09-30",
    "delta_days": 1,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "month",
    "old_precision": "day"
  },
  {
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "signal": "timeline_earlier_shift",
    "category": "timeline_shift",
    "new_type": "ESTIMATED",
    "old_type": "ESTIMATED",
    "severity": "medium",
    "direction": "earlier",
    "new_value": "2030-10",
    "old_value": "2032-03-31",
    "delta_days": 547,
    "date_struct": "completionDateStruct",
    "new_precision": "month",
    "old_precision": "day"
  },
  {
    "path": "/protocolSection/designModule/enrollmentInfo/count",
    "signal": "enrollment_count_change_ge_20pct",
    "category": "enrollment_change",
    "severity": "high",
    "new_value": 123,
    "old_value": 2032,
    "pct_change": 0.9395
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:44:36+00
Raw hash
2a9889a61a819c09e93705966e87267281c687e54a3205d1f0959c7c5a31a6f9
Payload
Source URL
Design Trial model, phase, allocation, masking, arms, or interventions. Triage: High 2 ops
replace /protocolSection/designModule/enrollmentInfo/count
Triage: High
Enrollment Change Operation 7
Matched rules
  • enrollment_count_change Enrollment count changes can signal scope or feasibility shifts.
Before
2032
After
123
replace /protocolSection/designModule/enrollmentInfo/type
Triage: High
Enrollment Change Operation 8
Matched rules
  • enrollment_type_change Enrollment type changes from anticipated to actual or similar are high review priority.
Before
ESTIMATED
After
ACTUAL
Timeline Start, primary completion, and completion date movement. Triage: Medium 2 ops
replace /protocolSection/statusModule/primaryCompletionDateStruct/date
Triage: Medium
Timeline Shift Operation 3
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
2030-09-30
After
2030-10
replace /protocolSection/statusModule/completionDateStruct/date
Triage: Medium
Timeline Shift Operation 4
Matched rules
  • completion_timeline_change Completion date changes are operational timeline signals.
Before
2032-03-31
After
2030-10
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 124 ops
remove /protocolSection/contactsLocationsModule/centralContacts
Triage: Low
Administrative Contact Change Operation 9
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
[
  {
    "name": "Doris Lanz",
    "role": "CONTACT",
    "email": "poetic-a-icrctsu@icr.ac.uk",
    "phone": "+44(0)2034376858"
  }
]
remove /protocolSection/contactsLocationsModule/locations/0/status
Triage: Uncategorized
Uncategorized Operation 10
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/0/contacts
Triage: Uncategorized
Uncategorized Operation 11
Before
[
  {
    "name": "Duncan Wheatley",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/1/status
Triage: Uncategorized
Uncategorized Operation 12
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/1/contacts
Triage: Uncategorized
Uncategorized Operation 13
Before
[
  {
    "name": "Douglas Ferguson",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/2/status
Triage: Uncategorized
Uncategorized Operation 14
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/2/contacts
Triage: Uncategorized
Uncategorized Operation 15
Before
[
  {
    "name": "Amy Burger",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/3/status
Triage: Uncategorized
Uncategorized Operation 16
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/3/contacts
Triage: Uncategorized
Uncategorized Operation 17
Before
[
  {
    "name": "Anne Kendal, MD",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/4/status
Triage: Uncategorized
Uncategorized Operation 18
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/4/contacts
Triage: Uncategorized
Uncategorized Operation 19
Before
[
  {
    "name": "Harieta Garofide",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/5/status
Triage: Uncategorized
Uncategorized Operation 20
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/5/contacts
Triage: Uncategorized
Uncategorized Operation 21
Before
[
  {
    "name": "Jonathan Thompson",
    "role": "CONTACT",
    "email": "jonathan.thompson@belfasttrust.hscni.net",
    "phone": "028 95 047850"
  },
  {
    "name": "Stuart McIntosh",
    "role": "PRINCIPAL_INVESTIGATOR"
  },
  {
    "name": "Jane Hurwitz",
    "role": "SUB_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/6/status
Triage: Uncategorized
Uncategorized Operation 22
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/6/contacts
Triage: Uncategorized
Uncategorized Operation 23
Before
[
  {
    "name": "Stephanie Brogan",
    "role": "CONTACT",
    "email": "stephanie.brogan@nhs.scot",
    "phone": "01324 566316"
  },
  {
    "name": "Anne Todd",
    "role": "CONTACT",
    "email": "anne.todd@nhs.scot",
    "phone": "01324 566316"
  },
  {
    "name": "Lucy Khan",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/7/status
Triage: Uncategorized
Uncategorized Operation 24
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/7/contacts
Triage: Uncategorized
Uncategorized Operation 25
Before
[
  {
    "name": "Claire Merrick",
    "role": "CONTACT",
    "email": "c.merrick1@nhs.net",
    "phone": "01483571122"
  },
  {
    "name": "R&D",
    "role": "CONTACT",
    "email": "mailto:rsc-tr.researchanddevelopment@nhs.net"
  },
  {
    "name": "Felicity Paterson",
    "role": "PRINCIPAL_INVESTIGATOR"
  },
  {
    "name": "Tracey Irvine",
    "role": "SUB_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/8/status
Triage: Uncategorized
Uncategorized Operation 26
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/8/contacts
Triage: Uncategorized
Uncategorized Operation 27
Before
[
  {
    "name": "Ravi Sharma, MD",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/9/status
Triage: Uncategorized
Uncategorized Operation 28
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/9/contacts
Triage: Uncategorized
Uncategorized Operation 29
Before
[
  {
    "name": "Najibah Mahtab",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/10/status
Triage: Uncategorized
Uncategorized Operation 30
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/10/contacts
Triage: Uncategorized
Uncategorized Operation 31
Before
[
  {
    "name": "Ilyas Khattak",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/11/status
Triage: Uncategorized
Uncategorized Operation 32
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/11/contacts
Triage: Uncategorized
Uncategorized Operation 33
Before
[
  {
    "name": "Mark Beresford",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/12/status
Triage: Uncategorized
Uncategorized Operation 34
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/12/contacts
Triage: Uncategorized
Uncategorized Operation 35
Before
[
  {
    "name": "Christina Yip",
    "role": "CONTACT"
  },
  {
    "name": "Christina Yip",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/13/status
Triage: Uncategorized
Uncategorized Operation 36
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/13/contacts
Triage: Uncategorized
Uncategorized Operation 37
Before
[
  {
    "name": "Pavel Bezecny",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/14/status
Triage: Uncategorized
Uncategorized Operation 38
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/14/contacts
Triage: Uncategorized
Uncategorized Operation 39
Before
[
  {
    "name": "Abhro Chaudhuri",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/15/status
Triage: Uncategorized
Uncategorized Operation 40
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/15/contacts
Triage: Uncategorized
Uncategorized Operation 41
Before
[
  {
    "name": "Anthony Skene",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/16/status
Triage: Uncategorized
Uncategorized Operation 42
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/16/contacts
Triage: Uncategorized
Uncategorized Operation 43
Before
[
  {
    "name": "Rathi Rathinaezhil",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/17/status
Triage: Uncategorized
Uncategorized Operation 44
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/17/contacts
Triage: Uncategorized
Uncategorized Operation 45
Before
[
  {
    "name": "Christina Yip",
    "role": "CONTACT"
  },
  {
    "name": "Christina Yip",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/18/status
Triage: Uncategorized
Uncategorized Operation 46
Before
ACTIVE_NOT_RECRUITING
remove /protocolSection/contactsLocationsModule/locations/19/status
Triage: Uncategorized
Uncategorized Operation 47
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/19/contacts
Triage: Uncategorized
Uncategorized Operation 48
Before
[
  {
    "name": "Aisling Hennessy",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/20/status
Triage: Uncategorized
Uncategorized Operation 49
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/20/contacts
Triage: Uncategorized
Uncategorized Operation 50
Before
[
  {
    "name": "Vassilis Pitsinis",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/21/status
Triage: Uncategorized
Uncategorized Operation 51
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/21/contacts
Triage: Uncategorized
Uncategorized Operation 52
Before
[
  {
    "name": "Caroline Michie",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/22/status
Triage: Uncategorized
Uncategorized Operation 53
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/22/contacts
Triage: Uncategorized
Uncategorized Operation 54
Before
[
  {
    "name": "James Mansell",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/23/status
Triage: Uncategorized
Uncategorized Operation 55
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/23/contacts
Triage: Uncategorized
Uncategorized Operation 56
Before
[
  {
    "name": "Werbena Hamilton Burke",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/24/status
Triage: Uncategorized
Uncategorized Operation 57
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/24/contacts
Triage: Uncategorized
Uncategorized Operation 58
Before
[
  {
    "name": "Biswajit Ray",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/25/status
Triage: Uncategorized
Uncategorized Operation 59
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/25/contacts
Triage: Uncategorized
Uncategorized Operation 60
Before
[
  {
    "name": "Werbena Hamilton Burke",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/26/status
Triage: Uncategorized
Uncategorized Operation 61
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/26/contacts
Triage: Uncategorized
Uncategorized Operation 62
Before
[
  {
    "name": "Paul Ridley",
    "role": "CONTACT",
    "email": "PAUL.RIDLEY@ESNEFT.NHS.UK",
    "phone": "01473 704389"
  },
  {
    "name": "Ramachandran Venkitaraman",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/27/status
Triage: Uncategorized
Uncategorized Operation 63
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/27/contacts
Triage: Uncategorized
Uncategorized Operation 64
Before
[
  {
    "name": "Salam Musa",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/28/status
Triage: Uncategorized
Uncategorized Operation 65
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/28/contacts
Triage: Uncategorized
Uncategorized Operation 66
Before
[
  {
    "name": "Marina Parton",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/29/status
Triage: Uncategorized
Uncategorized Operation 67
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/29/contacts
Triage: Uncategorized
Uncategorized Operation 68
Before
[
  {
    "name": "Sarah Moon",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/30/status
Triage: Uncategorized
Uncategorized Operation 69
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/30/contacts
Triage: Uncategorized
Uncategorized Operation 70
Before
[
  {
    "name": "Baek Kim",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/31/status
Triage: Uncategorized
Uncategorized Operation 71
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/31/contacts
Triage: Uncategorized
Uncategorized Operation 72
Before
[
  {
    "name": "Abhro Chaudhuri",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/32/status
Triage: Uncategorized
Uncategorized Operation 73
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/32/contacts
Triage: Uncategorized
Uncategorized Operation 74
Before
[
  {
    "name": "Caroline Michie",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/33/status
Triage: Uncategorized
Uncategorized Operation 75
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/33/contacts
Triage: Uncategorized
Uncategorized Operation 76
Before
[
  {
    "name": "Judy King",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/34/status
Triage: Uncategorized
Uncategorized Operation 77
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/34/contacts
Triage: Uncategorized
Uncategorized Operation 78
Before
[
  {
    "name": "Susan Cleator",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/35/status
Triage: Uncategorized
Uncategorized Operation 79
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/35/contacts
Triage: Uncategorized
Uncategorized Operation 80
Before
[
  {
    "name": "Amna Sheri",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/36/status
Triage: Uncategorized
Uncategorized Operation 81
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/36/contacts
Triage: Uncategorized
Uncategorized Operation 82
Before
[
  {
    "name": "Alistair Ring",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/37/status
Triage: Uncategorized
Uncategorized Operation 83
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/37/contacts
Triage: Uncategorized
Uncategorized Operation 84
Before
[
  {
    "name": "Muireann Kelleher",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/38/status
Triage: Uncategorized
Uncategorized Operation 85
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/38/contacts
Triage: Uncategorized
Uncategorized Operation 86
Before
[
  {
    "name": "Elsa Papadimitraki",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/39/status
Triage: Uncategorized
Uncategorized Operation 87
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/39/contacts
Triage: Uncategorized
Uncategorized Operation 88
Before
[
  {
    "name": "Michal Uhercik",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/40/status
Triage: Uncategorized
Uncategorized Operation 89
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/40/contacts
Triage: Uncategorized
Uncategorized Operation 90
Before
[
  {
    "name": "Nabila Nasir",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/41/status
Triage: Uncategorized
Uncategorized Operation 91
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/41/contacts
Triage: Uncategorized
Uncategorized Operation 92
Before
[
  {
    "name": "Sacha Howell",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/42/status
Triage: Uncategorized
Uncategorized Operation 93
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/42/contacts
Triage: Uncategorized
Uncategorized Operation 94
Before
[
  {
    "name": "Cliona Kirwan",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/43/status
Triage: Uncategorized
Uncategorized Operation 95
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/43/contacts
Triage: Uncategorized
Uncategorized Operation 96
Before
[
  {
    "name": "Carolyn Bedi",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/44/status
Triage: Uncategorized
Uncategorized Operation 97
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/44/contacts
Triage: Uncategorized
Uncategorized Operation 98
Before
[
  {
    "name": "Hany Eldeeb",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/45/status
Triage: Uncategorized
Uncategorized Operation 99
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/45/contacts
Triage: Uncategorized
Uncategorized Operation 100
Before
[
  {
    "name": "Najibah Mahtab",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/46/status
Triage: Uncategorized
Uncategorized Operation 101
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/46/contacts
Triage: Uncategorized
Uncategorized Operation 102
Before
[
  {
    "name": "Susan Lupton",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/47/status
Triage: Uncategorized
Uncategorized Operation 103
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/47/contacts
Triage: Uncategorized
Uncategorized Operation 104
Before
[
  {
    "name": "Annabel Borley",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/48/status
Triage: Uncategorized
Uncategorized Operation 105
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/48/contacts
Triage: Uncategorized
Uncategorized Operation 106
Before
[
  {
    "name": "Anthony Skene",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/49/status
Triage: Uncategorized
Uncategorized Operation 107
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/49/contacts
Triage: Uncategorized
Uncategorized Operation 108
Before
[
  {
    "name": "Madhumita Bhattacharyya",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/50/status
Triage: Uncategorized
Uncategorized Operation 109
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/50/contacts
Triage: Uncategorized
Uncategorized Operation 110
Before
[
  {
    "name": "Jagdeep Singh",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/51/status
Triage: Uncategorized
Uncategorized Operation 111
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/51/contacts
Triage: Uncategorized
Uncategorized Operation 112
Before
[
  {
    "name": "Julie Jones",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/52/status
Triage: Uncategorized
Uncategorized Operation 113
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/52/contacts
Triage: Uncategorized
Uncategorized Operation 114
Before
[
  {
    "name": "Laura Pettit",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/53/status
Triage: Uncategorized
Uncategorized Operation 115
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/53/contacts
Triage: Uncategorized
Uncategorized Operation 116
Before
[
  {
    "name": "Jennifer Lowry",
    "role": "CONTACT",
    "email": "Jenny.lowry@uhs.nhs.uk",
    "phone": "023 8120 4618"
  },
  {
    "name": "Ramsey Cutress",
    "role": "PRINCIPAL_INVESTIGATOR"
  },
  {
    "name": "Ellen Copson",
    "role": "SUB_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/54/status
Triage: Uncategorized
Uncategorized Operation 117
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/54/contacts
Triage: Uncategorized
Uncategorized Operation 118
Before
[
  {
    "name": "Janine Graham",
    "role": "PRINCIPAL_INVESTIGATOR"
  },
  {
    "name": "Dave Fung",
    "role": "SUB_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/55/status
Triage: Uncategorized
Uncategorized Operation 119
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/55/contacts
Triage: Uncategorized
Uncategorized Operation 120
Before
[
  {
    "name": "Daljit Gahir",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/56/status
Triage: Uncategorized
Uncategorized Operation 121
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/56/contacts
Triage: Uncategorized
Uncategorized Operation 122
Before
[
  {
    "name": "Alistair Ring",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/57/status
Triage: Uncategorized
Uncategorized Operation 123
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/57/contacts
Triage: Uncategorized
Uncategorized Operation 124
Before
[
  {
    "name": "Saiqa Spensley",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/58/status
Triage: Uncategorized
Uncategorized Operation 125
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/58/contacts
Triage: Uncategorized
Uncategorized Operation 126
Before
[
  {
    "name": "Zbigniew Kryjak",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/59/status
Triage: Uncategorized
Uncategorized Operation 127
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/59/contacts
Triage: Uncategorized
Uncategorized Operation 128
Before
[
  {
    "name": "Nawaz Walji",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
remove /protocolSection/contactsLocationsModule/locations/60/status
Triage: Uncategorized
Uncategorized Operation 129
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/60/contacts
Triage: Uncategorized
Uncategorized Operation 130
Before
[
  {
    "name": "Elena Takeuchi, MD",
    "role": "CONTACT"
  }
]
remove /protocolSection/contactsLocationsModule/locations/61/status
Triage: Uncategorized
Uncategorized Operation 131
Before
RECRUITING
remove /protocolSection/contactsLocationsModule/locations/61/contacts
Triage: Uncategorized
Uncategorized Operation 132
Before
[
  {
    "name": "Mark Churn",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2024-07
After
2026-01
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 5
Before
2024-07-06
After
2026-01-13
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 6
Before
2024-07-09
After
2026-01-14
Status and stopping reason Recruitment status, termination, suspension, withdrawal, or why-stopped text. Triage: Uncategorized 1 ops
replace /protocolSection/statusModule/overallStatus
Triage: Uncategorized
Uncategorized Operation 2
Before
RECRUITING
After
ACTIVE_NOT_RECRUITING
Raw JSON Patch
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2026-01"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/overallStatus",
    "value": "ACTIVE_NOT_RECRUITING"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2030-10"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/completionDateStruct/date",
    "value": "2030-10"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2026-01-13"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2026-01-14"
  },
  {
    "op": "replace",
    "path": "/protocolSection/designModule/enrollmentInfo/count",
    "value": 123
  },
  {
    "op": "replace",
    "path": "/protocolSection/designModule/enrollmentInfo/type",
    "value": "ACTUAL"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/centralContacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/1/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/1/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/2/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/2/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/3/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/3/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/4/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/4/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/5/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/5/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/6/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/6/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/7/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/7/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/8/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/8/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/9/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/9/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/10/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/10/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/11/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/11/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/12/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/12/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/13/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/13/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/14/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/14/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/15/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/15/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/16/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/16/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/17/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/17/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/18/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/19/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/19/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/20/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/20/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/21/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/21/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/22/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/22/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/23/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/23/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/24/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/24/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/25/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/25/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/26/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/26/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/27/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/27/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/28/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/28/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/29/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/29/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/30/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/30/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/31/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/31/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/32/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/32/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/33/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/33/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/34/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/34/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/35/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/35/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/36/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/36/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/37/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/37/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/38/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/38/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/39/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/39/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/40/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/40/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/41/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/41/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/42/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/42/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/43/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/43/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/44/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/44/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/45/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/45/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/46/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/46/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/47/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/47/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/48/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/48/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/49/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/49/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/50/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/50/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/51/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/51/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/52/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/52/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/53/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/53/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/54/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/54/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/55/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/55/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/56/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/56/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/57/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/57/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/58/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/58/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/59/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/59/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/60/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/60/contacts"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/61/status"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/61/contacts"
  }
]