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NCT04584853

PreOperative Endocrine Therapy for Individualised Care With Abemaciclib

Version 2 to 3 · Institute of Cancer Research, United Kingdom

Patch inspector

Version 2 to 3

10 operations 2 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:44:34+00
Raw hash
f6545e674441d7802bf5ed89721b4985d4f19d0a2d58f9e89143d2ec30931daa
Payload
Source URL
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 8 ops
replace /protocolSection/contactsLocationsModule/centralContacts/0/name
Triage: Low
Administrative Contact Change Operation 3
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
Lorna Smith
After
Doris Lanz
replace /protocolSection/contactsLocationsModule/centralContacts/0/phone
Triage: Low
Administrative Contact Change Operation 4
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
+44(0)2087224264
After
+44(0)2034376858
replace /protocolSection/contactsLocationsModule/locations/0/status
Triage: Uncategorized
Uncategorized Operation 5
Before
NOT_YET_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/7
Triage: Uncategorized
Uncategorized Operation 6
After
{
  "zip": "BB2 3HH",
  "city": "Blackburn",
  "status": "RECRUITING",
  "country": "United Kingdom",
  "contacts": [
    {
      "name": "Christina Yip",
      "role": "CONTACT"
    },
    {
      "name": "Christina Yip",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Royal Blackburn Hospital",
  "geoPoint": {
    "lat": 53.75,
    "lon": -2.48333
  }
}
add /protocolSection/contactsLocationsModule/locations/11
Triage: Uncategorized
Uncategorized Operation 7
After
{
  "zip": "BB10 2PQ",
  "city": "Burnley",
  "status": "RECRUITING",
  "country": "United Kingdom",
  "contacts": [
    {
      "name": "Christina Yip",
      "role": "CONTACT"
    },
    {
      "name": "Christina Yip",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Burnley General Hospital",
  "geoPoint": {
    "lat": 53.8,
    "lon": -2.23333
  }
}
add /protocolSection/contactsLocationsModule/locations/16
Triage: Uncategorized
Uncategorized Operation 8
After
{
  "zip": "IP4 5PD",
  "city": "Ipswich",
  "status": "RECRUITING",
  "country": "United Kingdom",
  "contacts": [
    {
      "name": "Paul Ridley",
      "role": "CONTACT",
      "email": "PAUL.RIDLEY@ESNEFT.NHS.UK",
      "phone": "01473 704389"
    },
    {
      "name": "Ramachandran Venkitaraman",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Ipswich Hospital",
  "geoPoint": {
    "lat": 52.05917,
    "lon": 1.15545
  }
}
replace /protocolSection/contactsLocationsModule/locations/27/status
Triage: Uncategorized
Uncategorized Operation 9
Before
ACTIVE_NOT_RECRUITING
After
RECRUITING
add /protocolSection/contactsLocationsModule/locations/27/contacts
Triage: Uncategorized
Uncategorized Operation 10
After
[
  {
    "name": "Zbigniew Kryjak",
    "role": "PRINCIPAL_INVESTIGATOR"
  }
]
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 2 ops
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2022-02-16
After
2022-06-14
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 2
Before
2022-02-17
After
2022-06-15
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2022-06-14"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2022-06-15"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/name",
    "value": "Doris Lanz"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/phone",
    "value": "+44(0)2034376858"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/0/status",
    "value": "RECRUITING"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/7",
    "value": {
      "zip": "BB2 3HH",
      "city": "Blackburn",
      "status": "RECRUITING",
      "country": "United Kingdom",
      "contacts": [
        {
          "name": "Christina Yip",
          "role": "CONTACT"
        },
        {
          "name": "Christina Yip",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "Royal Blackburn Hospital",
      "geoPoint": {
        "lat": 53.75,
        "lon": -2.48333
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/11",
    "value": {
      "zip": "BB10 2PQ",
      "city": "Burnley",
      "status": "RECRUITING",
      "country": "United Kingdom",
      "contacts": [
        {
          "name": "Christina Yip",
          "role": "CONTACT"
        },
        {
          "name": "Christina Yip",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "Burnley General Hospital",
      "geoPoint": {
        "lat": 53.8,
        "lon": -2.23333
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/16",
    "value": {
      "zip": "IP4 5PD",
      "city": "Ipswich",
      "status": "RECRUITING",
      "country": "United Kingdom",
      "contacts": [
        {
          "name": "Paul Ridley",
          "role": "CONTACT",
          "email": "PAUL.RIDLEY@ESNEFT.NHS.UK",
          "phone": "01473 704389"
        },
        {
          "name": "Ramachandran Venkitaraman",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "Ipswich Hospital",
      "geoPoint": {
        "lat": 52.05917,
        "lon": 1.15545
      }
    }
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/27/status",
    "value": "RECRUITING"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/27/contacts",
    "value": [
      {
        "name": "Zbigniew Kryjak",
        "role": "PRINCIPAL_INVESTIGATOR"
      }
    ]
  }
]