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NCT04756765

Talazoparib Monotherapy in PALB2 Mutation Associated Advanced Breast Cancer

Version 7 to 8 · Stanford University

Patch inspector

Version 7 to 8

4 operations 2 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/startDateStruct/type",
    "signal": "milestone_realized",
    "category": "milestone_realized",
    "new_date": "2023-02-23",
    "new_type": "ACTUAL",
    "old_date": "2023-02-23",
    "old_type": "ESTIMATED",
    "severity": "low",
    "delta_days": 0,
    "date_struct": "startDateStruct"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:13:22+00
Raw hash
0df236381ab0025f24a27df70a50704becbe16aab76fc1a3bed8b0a007f2bc56
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 1 ops
replace /protocolSection/statusModule/startDateStruct/type
Triage: Medium
Timeline Shift Operation 2
Matched rules
  • start_timeline_change Start date changes are operational timeline signals.
Before
ESTIMATED
After
ACTUAL
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2023-02
After
2023-05
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2023-02-27
After
2023-05-23
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2023-03-01
After
2023-05-25
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2023-05"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/startDateStruct/type",
    "value": "ACTUAL"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2023-05-23"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2023-05-25"
  }
]