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NCT05549505

A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery

Version 6 to 7 · Arvinas Inc.

Patch inspector

Version 6 to 7

4 operations 2 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired

None recorded.

Value signals
[
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "signal": "timeline_actualized_earlier",
    "category": "timeline_actualized_earlier",
    "new_type": "ACTUAL",
    "old_type": "ESTIMATED",
    "severity": "low",
    "direction": "earlier",
    "new_value": "2024-07-13",
    "old_value": "2024-07-15",
    "delta_days": 2,
    "date_struct": "primaryCompletionDateStruct",
    "new_precision": "day",
    "old_precision": "day"
  },
  {
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/type",
    "signal": "milestone_realized",
    "category": "milestone_realized",
    "new_date": "2024-07-13",
    "new_type": "ACTUAL",
    "old_date": "2024-07-15",
    "old_type": "ESTIMATED",
    "severity": "low",
    "delta_days": 2,
    "date_struct": "primaryCompletionDateStruct"
  }
]
Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:11:38+00
Raw hash
7a9b37a23f3a2390dc91e7dfc30f6e8a24cc42c3ad9c4f01f473f151b2dbc3cd
Payload
Source URL
Timeline Start, primary completion, and completion date movement. Triage: Medium 2 ops
replace /protocolSection/statusModule/primaryCompletionDateStruct/date
Triage: Medium
Timeline Shift Operation 1
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
2024-07-15
After
2024-07-13
replace /protocolSection/statusModule/primaryCompletionDateStruct/type
Triage: Medium
Timeline Shift Operation 2
Matched rules
  • primary_completion_timeline_change Primary completion date changes are operational timeline signals.
Before
ESTIMATED
After
ACTUAL
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 2 ops
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 3
Before
2024-05-06
After
2024-08-02
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 4
Before
2024-05-07
After
2024-08-05
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/date",
    "value": "2024-07-13"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/primaryCompletionDateStruct/type",
    "value": "ACTUAL"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2024-08-02"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2024-08-05"
  }
]