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NCT05748834

Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

Version 4 to 5 · SCRI Development Innovations, LLC

Patch inspector

Version 4 to 5

8 operations 2 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:00:35+00
Raw hash
60507db43d00ec42e03b92de37a5df36d40b6f328a43378cf1206a91990eda16
Payload
Source URL
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 5 ops
replace /protocolSection/contactsLocationsModule/centralContacts/0/phone
Triage: Low
Administrative Contact Change Operation 4
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
615-329-7274
After
1-844-710-6157
replace /protocolSection/contactsLocationsModule/centralContacts/0/email
Triage: Low
Administrative Contact Change Operation 5
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
CANN.SCRIInnovationsEnr@scri-innovations.com
After
SCRI.InnovationsMedical@scri.com
replace /protocolSection/contactsLocationsModule/locations/0/facility
Triage: Uncategorized
Uncategorized Operation 6
Before
Tennessee Oncology
After
SCRI Oncology Partners
remove /protocolSection/contactsLocationsModule/locations/0/contacts
Triage: Uncategorized
Uncategorized Operation 7
Before
[
  {
    "name": "Erika Hamilton, MD",
    "role": "CONTACT"
  }
]
add /protocolSection/contactsLocationsModule/locations/1
Triage: Uncategorized
Uncategorized Operation 8
After
{
  "zip": "37203",
  "city": "Nashville",
  "state": "Tennessee",
  "status": "ACTIVE_NOT_RECRUITING",
  "country": "United States",
  "facility": "Tennessee Oncology",
  "geoPoint": {
    "lat": 36.16589,
    "lon": -86.78444
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2023-08
After
2024-01
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 2
Before
2023-08-01
After
2024-01-22
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 3
Before
2023-08-02
After
2024-01-24
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2024-01"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2024-01-22"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2024-01-24"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/phone",
    "value": "1-844-710-6157"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/email",
    "value": "SCRI.InnovationsMedical@scri.com"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/locations/0/facility",
    "value": "SCRI Oncology Partners"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/locations/0/contacts"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/1",
    "value": {
      "zip": "37203",
      "city": "Nashville",
      "state": "Tennessee",
      "status": "ACTIVE_NOT_RECRUITING",
      "country": "United States",
      "facility": "Tennessee Oncology",
      "geoPoint": {
        "lat": 36.16589,
        "lon": -86.78444
      }
    }
  }
]