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NCT06923527

Circulating Tumor DNA

Version 7 to 8 · Yale University

Patch inspector

Version 7 to 8

12 operations 2 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 18:57:46+00
Raw hash
d61bce46ce01d42745e19d2e5cfc651d7a914a619da23d43a38fc6fdb60fd65a
Payload
Source URL
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 9 ops
replace /protocolSection/contactsLocationsModule/centralContacts/0/name
Triage: Low
Administrative Contact Change Operation 4
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
Stephanie Ladd
After
Laura Kane
replace /protocolSection/contactsLocationsModule/centralContacts/0/phone
Triage: Low
Administrative Contact Change Operation 5
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
954-895-0576
After
773-369-6904
replace /protocolSection/contactsLocationsModule/centralContacts/0/email
Triage: Low
Administrative Contact Change Operation 6
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
stephanie.ladd@yale.edu
After
laura.kane@yale.edu
add /protocolSection/contactsLocationsModule/locations/1
Triage: Uncategorized
Uncategorized Operation 7
After
{
  "zip": "20007",
  "city": "Washington D.C.",
  "state": "District of Columbia",
  "status": "NOT_YET_RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Lana Kheir",
      "role": "CONTACT",
      "email": "lk814@georgetown.edu",
      "phone": "202-444-2223"
    },
    {
      "name": "Katia Khoury, MD",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Lombardi Comprehensive Cancer Center at Georgetown University Medical Center",
  "geoPoint": {
    "lat": 38.89511,
    "lon": -77.03637
  }
}
add /protocolSection/contactsLocationsModule/locations/2
Triage: Uncategorized
Uncategorized Operation 8
After
{
  "zip": "21287",
  "city": "Baltimore",
  "state": "Maryland",
  "status": "NOT_YET_RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Sharon White",
      "role": "CONTACT",
      "email": "HopkinsBreastTrials@jhmi.edu",
      "phone": "410-614-1361"
    },
    {
      "name": "Jenna Canzoniero, MD",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Sidney Kimmel Comprehensive Cancer Center at John Hopkins",
  "geoPoint": {
    "lat": 39.29038,
    "lon": -76.61219
  }
}
add /protocolSection/contactsLocationsModule/locations/3
Triage: Uncategorized
Uncategorized Operation 9
After
{
  "zip": "02215",
  "city": "Boston",
  "state": "Massachusetts",
  "status": "NOT_YET_RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Ilana Schlam Camhi, MD MPH",
      "role": "CONTACT",
      "email": "ilana_schlam@dfci.harvard.edu",
      "phone": "8773387425"
    },
    {
      "name": "Ilana M Schlam Camhi, MD MPH",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Dana-Farber Cancer Institute",
  "geoPoint": {
    "lat": 42.35843,
    "lon": -71.05977
  }
}
add /protocolSection/contactsLocationsModule/locations/4
Triage: Uncategorized
Uncategorized Operation 10
After
{
  "zip": "10461",
  "city": "The Bronx",
  "state": "New York",
  "status": "NOT_YET_RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Fernando Gonterman",
      "role": "CONTACT",
      "email": "fgonterman@montefiore.org",
      "phone": "718-405-8126"
    },
    {
      "name": "Jesus Anampa, MD",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "Montefiore Einstein Comprehensive Cancer Center",
  "geoPoint": {
    "lat": 40.84985,
    "lon": -73.86641
  }
}
add /protocolSection/contactsLocationsModule/locations/5
Triage: Uncategorized
Uncategorized Operation 11
After
{
  "zip": "15232",
  "city": "Pittsburgh",
  "state": "Pennsylvania",
  "status": "NOT_YET_RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Joshua Plassmeyer, 412-648-6417",
      "role": "CONTACT",
      "email": "plassmeyerjm@upmc.edu"
    },
    {
      "name": "Julia Foldi, MD PhD",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "UPMC Hillman Cancer Center",
  "geoPoint": {
    "lat": 40.44062,
    "lon": -79.99589
  }
}
add /protocolSection/contactsLocationsModule/locations/6
Triage: Uncategorized
Uncategorized Operation 12
After
{
  "zip": "77030",
  "city": "Houston",
  "state": "Texas",
  "status": "NOT_YET_RECRUITING",
  "country": "United States",
  "contacts": [
    {
      "name": "Pamela Lewis",
      "role": "CONTACT",
      "email": "plewis@mdanderson.org",
      "phone": "713-563-4527"
    },
    {
      "name": "Carlos H Barcenas, MD MSc",
      "role": "PRINCIPAL_INVESTIGATOR"
    }
  ],
  "facility": "The University of Texas MD Anderson Cancer Center",
  "geoPoint": {
    "lat": 29.76328,
    "lon": -95.36327
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2025-06
After
2026-02
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 2
Before
2025-12-18
After
2026-03-12
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 3
Before
2025-12-22
After
2026-03-16
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2026-02"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2026-03-12"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2026-03-16"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/name",
    "value": "Laura Kane"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/phone",
    "value": "773-369-6904"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/email",
    "value": "laura.kane@yale.edu"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/1",
    "value": {
      "zip": "20007",
      "city": "Washington D.C.",
      "state": "District of Columbia",
      "status": "NOT_YET_RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Lana Kheir",
          "role": "CONTACT",
          "email": "lk814@georgetown.edu",
          "phone": "202-444-2223"
        },
        {
          "name": "Katia Khoury, MD",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "Lombardi Comprehensive Cancer Center at Georgetown University Medical Center",
      "geoPoint": {
        "lat": 38.89511,
        "lon": -77.03637
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/2",
    "value": {
      "zip": "21287",
      "city": "Baltimore",
      "state": "Maryland",
      "status": "NOT_YET_RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Sharon White",
          "role": "CONTACT",
          "email": "HopkinsBreastTrials@jhmi.edu",
          "phone": "410-614-1361"
        },
        {
          "name": "Jenna Canzoniero, MD",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "Sidney Kimmel Comprehensive Cancer Center at John Hopkins",
      "geoPoint": {
        "lat": 39.29038,
        "lon": -76.61219
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/3",
    "value": {
      "zip": "02215",
      "city": "Boston",
      "state": "Massachusetts",
      "status": "NOT_YET_RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Ilana Schlam Camhi, MD MPH",
          "role": "CONTACT",
          "email": "ilana_schlam@dfci.harvard.edu",
          "phone": "8773387425"
        },
        {
          "name": "Ilana M Schlam Camhi, MD MPH",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "Dana-Farber Cancer Institute",
      "geoPoint": {
        "lat": 42.35843,
        "lon": -71.05977
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/4",
    "value": {
      "zip": "10461",
      "city": "The Bronx",
      "state": "New York",
      "status": "NOT_YET_RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Fernando Gonterman",
          "role": "CONTACT",
          "email": "fgonterman@montefiore.org",
          "phone": "718-405-8126"
        },
        {
          "name": "Jesus Anampa, MD",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "Montefiore Einstein Comprehensive Cancer Center",
      "geoPoint": {
        "lat": 40.84985,
        "lon": -73.86641
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/5",
    "value": {
      "zip": "15232",
      "city": "Pittsburgh",
      "state": "Pennsylvania",
      "status": "NOT_YET_RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Joshua Plassmeyer, 412-648-6417",
          "role": "CONTACT",
          "email": "plassmeyerjm@upmc.edu"
        },
        {
          "name": "Julia Foldi, MD PhD",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "UPMC Hillman Cancer Center",
      "geoPoint": {
        "lat": 40.44062,
        "lon": -79.99589
      }
    }
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/6",
    "value": {
      "zip": "77030",
      "city": "Houston",
      "state": "Texas",
      "status": "NOT_YET_RECRUITING",
      "country": "United States",
      "contacts": [
        {
          "name": "Pamela Lewis",
          "role": "CONTACT",
          "email": "plewis@mdanderson.org",
          "phone": "713-563-4527"
        },
        {
          "name": "Carlos H Barcenas, MD MSc",
          "role": "PRINCIPAL_INVESTIGATOR"
        }
      ],
      "facility": "The University of Texas MD Anderson Cancer Center",
      "geoPoint": {
        "lat": 29.76328,
        "lon": -95.36327
      }
    }
  }
]