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NCT02576431

A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors

Version 0 to 1 · Bayer

Patch inspector

Version 0 to 1

8 operations 2 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:12:13+00
Raw hash
243129e2cf9058d721d7e36e69ca60d6b447a17c63c13608fa70f6d63ef143ad
Payload
Source URL
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 5 ops
replace /protocolSection/contactsLocationsModule/centralContacts/0/name
Triage: Low
Administrative Contact Change Operation 4
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
Michele Fernandes
After
Maegan Deegan
add /protocolSection/contactsLocationsModule/centralContacts/0/email
Triage: Low
Administrative Contact Change Operation 5
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
After
maegan@loxooncology.com
replace /protocolSection/contactsLocationsModule/centralContacts/1/name
Triage: Low
Administrative Contact Change Operation 6
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
Maegan Deegan
After
Michele Fernandes
remove /protocolSection/contactsLocationsModule/centralContacts/1/email
Triage: Low
Administrative Contact Change Operation 7
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
maegan@loxooncology.com
add /protocolSection/contactsLocationsModule/locations/1
Triage: Uncategorized
Uncategorized Operation 8
After
{
  "zip": "77030",
  "city": "Houston",
  "state": "Texas",
  "status": "RECRUITING",
  "country": "United States",
  "facility": "MD Anderson Cancer Center",
  "geoPoint": {
    "lat": 29.76328,
    "lon": -95.36327
  }
}
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2015-10
After
2015-12
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 2
Before
2015-10-13
After
2015-12-04
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 3
Before
2015-10-15
After
2015-12-08
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2015-12"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2015-12-04"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2015-12-08"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/name",
    "value": "Maegan Deegan"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/0/email",
    "value": "maegan@loxooncology.com"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/1/name",
    "value": "Michele Fernandes"
  },
  {
    "op": "remove",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/1/email"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/locations/1",
    "value": {
      "zip": "77030",
      "city": "Houston",
      "state": "Texas",
      "status": "RECRUITING",
      "country": "United States",
      "facility": "MD Anderson Cancer Center",
      "geoPoint": {
        "lat": 29.76328,
        "lon": -95.36327
      }
    }
  }
]