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NCT02576431

A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors

Version 1 to 2 · Bayer

Patch inspector

Version 1 to 2

6 operations 2 path groups ctgov_internal_history
ClinicalTrials.gov
Severity is deterministic uncalibrated triage metadata, not validated review priority. Operation-level severity is inferred from deterministic path rules. Rule matches shown per operation are approximate previews (they skip the pipeline's suppression passes); the authoritative classification is the stored event record.
Plain-language summary

Manual review pending.

Rules fired
contact_admin_change
Value signals

None recorded.

Provenance
Source
ctgov_internal_history
Fetched
2026-06-18 19:12:13+00
Raw hash
f9e8c02b8dfb153301fd2e46ca2217ed2771b0b74af15775cc0419a8baf01af6
Payload
Source URL
Contacts and locations Site, contact, and location updates that are usually operational. Triage: Low 3 ops
replace /protocolSection/contactsLocationsModule/centralContacts/1/name
Triage: Low
Administrative Contact Change Operation 4
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
Before
Michele Fernandes
After
Lia Donahue
add /protocolSection/contactsLocationsModule/centralContacts/1/phone
Triage: Low
Administrative Contact Change Operation 5
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
After
1-855-NTRK-123
add /protocolSection/contactsLocationsModule/centralContacts/1/email
Triage: Low
Administrative Contact Change Operation 6
Matched rules
  • contact_admin_change Central contact updates are usually administrative.
After
lia@loxooncology.com
Other registry fields Changes outside the current high-signal rule families. Triage: Uncategorized 3 ops
replace /protocolSection/statusModule/statusVerifiedDate
Triage: Uncategorized
Uncategorized Operation 1
Before
2015-12
After
2016-01
replace /protocolSection/statusModule/lastUpdateSubmitDate
Triage: Uncategorized
Uncategorized Operation 2
Before
2015-12-04
After
2016-01-26
replace /protocolSection/statusModule/lastUpdatePostDateStruct/date
Triage: Uncategorized
Uncategorized Operation 3
Before
2015-12-08
After
2016-01-27
Raw JSON Patch 
[
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/statusVerifiedDate",
    "value": "2016-01"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdateSubmitDate",
    "value": "2016-01-26"
  },
  {
    "op": "replace",
    "path": "/protocolSection/statusModule/lastUpdatePostDateStruct/date",
    "value": "2016-01-27"
  },
  {
    "op": "replace",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/1/name",
    "value": "Lia Donahue"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/1/phone",
    "value": "1-855-NTRK-123"
  },
  {
    "op": "add",
    "path": "/protocolSection/contactsLocationsModule/centralContacts/1/email",
    "value": "lia@loxooncology.com"
  }
]