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NCT04482309

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors

A Phase 2, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Trastuzumab Deruxtecan (T-DXd, DS-8201a) for the Treatment of Selected HER2 Expressing Tumors (DESTINY-PanTumor02)

ClinicalTrials.gov
Sponsor
AstraZeneca
Status
Active Not Recruiting
Versions
52
Adjacent patches
51
Severity is deterministic, reproducible, uncalibrated triage metadata, not validated review priority or proven wrongdoing. New Evidence Record packages are generated for deterministic event-class membership, not by triage rank alone.

Material event timeline

10 shown
Triage: Low
2020-09-09
Timeline Minor Adjustment
v0 to v1 Pre Recruitment Inspect patch
/protocolSection/contactsLocationsModule/locations/0/status
/protocolSection/contactsLocationsModule/locations/1/city
/protocolSection/contactsLocationsModule/locations/1/country
Triage: High
2021-06-08
Eligibility Change
v9 to v10 Early Recruitment Inspect patch
/protocolSection/contactsLocationsModule/locations/0/status
/protocolSection/contactsLocationsModule/locations/10/status
/protocolSection/contactsLocationsModule/locations/102
Triage: Medium
2022-04-14
Timeline Shift
v19 to v20 Early Recruitment Inspect patch
/protocolSection/contactsLocationsModule/locations/105/status
/protocolSection/contactsLocationsModule/locations/49
/protocolSection/contactsLocationsModule/locations/88/status
Triage: Low
2022-06-08
Timeline Minor Adjustment
v21 to v22 Early Recruitment Inspect patch
/protocolSection/statusModule/completionDateStruct/date
/protocolSection/statusModule/lastUpdatePostDateStruct/date
/protocolSection/statusModule/lastUpdateSubmitDate
Triage: High
2022-07-14
Enrollment Change
v22 to v23 Early Recruitment Inspect patch
/protocolSection/contactsLocationsModule/centralContacts
/protocolSection/contactsLocationsModule/locations/0/city
/protocolSection/contactsLocationsModule/locations/0/geoPoint/lat
Triage: Critical
2023-07-07
Primary Outcome Change
v27 to v28 Late Recruitment Inspect patch
/protocolSection/descriptionModule/briefSummary
/protocolSection/designModule/enrollmentInfo/count
/protocolSection/designModule/enrollmentInfo/type
Triage: Critical
2024-02-05
Primary Outcome Change
v28 to v29 Late Recruitment Inspect patch Evidence Record
/protocolSection/armsInterventionsModule/armGroups/0/description
/protocolSection/armsInterventionsModule/armGroups/0/label
/protocolSection/armsInterventionsModule/armGroups/1/description
Triage: High
2024-05-21
Timeline Major Slip
v29 to v30 Late Recruitment Inspect patch
/protocolSection/contactsLocationsModule/centralContacts
/protocolSection/contactsLocationsModule/locations/0/city
/protocolSection/contactsLocationsModule/locations/0/geoPoint/lat
Triage: High
2026-03-26
Enrollment Change
v49 to v50 Early Recruitment Inspect patch
/protocolSection/contactsLocationsModule/centralContacts
/protocolSection/contactsLocationsModule/locations/0/city
/protocolSection/contactsLocationsModule/locations/0/geoPoint/lat
Triage: Low
2026-04-08
Timeline Minor Adjustment
v50 to v51 Late Recruitment Inspect patch
/protocolSection/statusModule/completionDateStruct/date
/protocolSection/statusModule/lastUpdatePostDateStruct/date
/protocolSection/statusModule/lastUpdateSubmitDate