Severity is deterministic, reproducible, uncalibrated triage metadata, not validated review priority or proven wrongdoing. Evidence Records state what the registry history supports and what it does not support.
Serious Adverse Event Removalv201 to v202Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT02086578 · Study Assessing the Potential for Reduced Rates of Implant Failure Using Multi-Beam Intensity-Modulated Radiation Therapy for Locally Advanced Breast Cancer Patients With Implant Reconstructions
Design Changev23 to v24Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT05549505 · A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery
Arm Intervention Changev8 to v9Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT04588246 · Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery
Arm Intervention Changev17 to v18Post RecruitmentEvidence v1Results posting co-occurs
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT05243641 · Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test
Adverse Event Group Changev16 to v17Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT02229084 · Vaccination of High Risk Breast Cancer Patients
Arm Intervention Changev16 to v17Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT03152929 · Paravertebral Block (PVC) Versus Pectoral Nerve Block (PEC)
Enrollment Changev3 to v4Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT03735680 · A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer
Serious Adverse Event Modificationv9 to v10Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT03735680 · A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer
Arm Intervention Changev8 to v9Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT00691678 · Glucosamine and Chondroitin for Aromatase Inhibitor Induced Joint Symptoms in Women With Breast Cancer
Arm Intervention Changev6 to v7Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT00530868 · Comparing Letrozole Given Alone to Letrozole Given With Avastin in Post-Menopausal Women Breast Cancer
Arm Intervention Changev26 to v27Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT02340221 · A Study of Taselisib + Fulvestrant Versus Placebo + Fulvestrant in Participants With Advanced or Metastatic Breast Cancer Who Have Disease Recurrence or Progression During or After Aromatase Inhibitor Therapy
Status Terminationv62 to v63Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT03584009 · A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy
Arm Intervention Changev24 to v25Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT01033032 · Trial of Amrubicin as Treatment for Patients With HER2-Negative Metastatic Breast Cancer
Arm Intervention Changev16 to v17Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT02384239 · A Study of Palbociclib in Combination With Fulvestrant or Tamoxifen as Treatment for Metastatic Breast Cancer
Arm Intervention Changev8 to v9Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT02137252 · Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast Cancer
Arm Intervention Changev6 to v7Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT00879086 · A Study Comparing Eribulin Mesylate and Ixabepilone in Causing or Exacerbating Neuropathy in Participants With Advanced Breast Cancer
Arm Intervention Changev8 to v9Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT03584009 · A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy
Arm Intervention Changev22 to v23Post RecruitmentEvidence v1Results posting co-occurs
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT01556243 · Breast-Conserving Surgery and Radiation Therapy in Patients With Multiple Ipsilateral Breast Cancer
Other Adverse Event Modificationv29 to v30Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT05415215 · A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer
Results Reconciliationv30 to v31Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT05415215 · A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer
Results Reconciliationv29 to v30Post RecruitmentEvidence v1Results posting co-occurs
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT03535506 · Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery
Results Reconciliationv8 to v9Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT05549505 · A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery
Results Reconciliationv9 to v10Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT03094169 · AVID100 in Advanced Epithelial Carcinomas
Results Reconciliationv12 to v13Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT05243641 · Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test
Results Reconciliationv18 to v19Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT05243641 · Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test
Results Reconciliationv17 to v18Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
NCT05243641 · Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test
Results Reconciliationv15 to v16Post RecruitmentEvidence v1Results posting co-occurs
outcome_edit_cooccurs_with_results_posting
Outcome paths changed while results were added. Treat as a deterministic triage
results-posting/reconciliation record, not a standalone outcome-switching example.
A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors
Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease
Enrollment Changev6 to v7Early RecruitmentHuman review
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Eligibility Changev1 to v2Early RecruitmentHuman review
Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery
Serious Adverse Event Modificationv18 to v19Post RecruitmentHuman review
A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer
Enrollment Changev29 to v30Early RecruitmentHuman review
Multigene Risk Score Combined With Ki-67 Dynamic Assessment in Stratified Neoadjuvant Endocrine Therapy Treatment With or Without CDK4/6 Inhibitors in HR+/HER2- Breast Cancer
A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02)
Serious Adverse Event Additionv13 to v14Late RecruitmentHuman reviewResults posting co-occursEvidence Record
Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.
Timeline Significant Shiftv66 to v67Late Recruitment
A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors
Timeline Significant Shiftv9 to v10Late Recruitment
Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy
Status Terminationv3 to v4Early RecruitmentHuman reviewResults posting co-occursEvidence Record
Study Assessing the Potential for Reduced Rates of Implant Failure Using Multi-Beam Intensity-Modulated Radiation Therapy for Locally Advanced Breast Cancer Patients With Implant Reconstructions
Design Changev23 to v24Post RecruitmentHuman reviewResults posting co-occursEvidence Record
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Timeline Actualized Earlierv0 to v1Pre Recruitment
A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer
Results Reconciliationv30 to v31Post RecruitmentResults posting co-occursEvidence Record
Evaluating the Safety, Tolerability, and Preliminary Anti-tumor Activity of MB0151 in Adult Subjects With Advanced Solid Tumors Expressing Somatostatin Receptors
Eligibility Changev2 to v3Early RecruitmentHuman review
A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors
Timeline Significant Shiftv8 to v9Late Recruitment
A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer
Results Reconciliationv29 to v30Post RecruitmentResults posting co-occursEvidence Record